NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Bristol N2;
DOI=10.1126/science.282.5396.2012; PubMed=9851916 [NCBI, ExPASy, EBI, Israel, Japan]
The C. elegans sequencing consortium;
"Genome sequence of the nematode C. elegans: a platform for investigating biology.";
Science 282:2012-2018(1998).

Comments

CATALYTIC ACTIVITY: L-proline + NAD(P)⁺ = 1-pyrroline-5-carboxylate + NAD(P)H.
PATHWAY: Amino-acid biosynthesis; L-proline biosynthesis; L-proline from L-glutamate 5-semialdehyde: step 1/1 .
SIMILARITY: Belongs to the pyrroline-5-carboxylate reductase family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

U58750; AAB00645.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

T29226; T29226.

NP_501199.1; -.

3D structure databases

ModBase

Q20848.

Organism-specific databases

WormBase

WBGene00018904; F55G1.9.

WormPep

F55G1.9; CE07286. [WormPep / WorfDB]

Gene expression databases

ArrayExpress

Q20848; -.

Family and domain databases

InterPro

IPR004455; NADP_OxRdtase_F420.
IPR000304; P5CR.
Graphical view of domain structure.

PANTHER

PTHR11645; P5CR; 1.

Pfam

PF03807; F420_oxidored; 1.
Pfam graphical view of domain structure.

PIRSF

PIRSF000193; Pyrrol-5-carb_rd; 1.

TIGR00112; proC; 1.

PS00521; P5CR; 1.

Genome annotation databases

Ensembl

F55G1.9; Caenorhabditis elegans. [Contig view]

GeneID

177519; -.

KEGG

cel:F55G1.9; -.

NMPDR

fig|6239.3.peg.13938; -.

Other

ProtoNet

Q20848.

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Amino-acid biosynthesis; Complete proteome; NADP; Oxidoreductase; Proline biosynthesis.

Features

Feature table viewer

`Key`	`From To`	`Length`		`Description`	`FTId`
`CHAIN`	`1 299`	`299`		`Putative pyrroline-5-carboxylate reductase.`	`PRO_0000187321`

Sequence information

Length: 299 AA [This is the length of the unprocessed precursor]

Molecular weight: 32057 Da [This is the MW of the unprocessed precursor]

CRC64: 75D2D6D32E0A5670 [This is a checksum on the sequence]

        10         20         30         40         50         60 
MTIDTELTNG SSESVPFVFI GGGNMAAAII KGCQNKGFTP KSNIVIGVQT EKSAEKWRQL 

        70         80         90        100        110        120 
GYKNVFTNTL EMLERYSTAI YVICVKPQVF EEVVSSWPVN SRPEFIISVM AGVPLKVLNA 

       130        140        150        160        170        180 
KLPFVSGNTT IVRLMPNVAS SIGAGASTMC YEKNEKIMNQ DSHIELAREF AECVGTVELI 

       190        200        210        220        230        240 
PERCFNPAMA IGGSSPAWTF MYIESLADGA VAQGLGRAEA KRLAAQAVLG AAQMVLNSNS 

       250        260        270        280        290 
GFDIETQHFG SLKDMVCSPG GTTIEGVRAL EKNGFRYAVM EAVVAASTKA DEMAKSLAK

Q20848 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools