NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=U-51;
TISSUE=Gametophyte;
Kunimoto M., Morishima K., Yoshikawa M., Fukuda S., Kobayashi T., Kobayashi M., Okazaki T., Ohara I., Nakayama I.;
"Whole genome sequence of Porphyra yezoensis chloroplast.";
Submitted (NOV-2003) to the EMBL/GenBank/DDBJ databases.

Comments

FUNCTION: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).
CATALYTIC ACTIVITY: Pyruvate + [dihydrolipoyllysine-residue acetyltransferase] lipoyllysine = [dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine + CO₂.
COFACTOR: Thiamine pyrophosphate.
SUBUNIT: Heterodimer of an alpha and a beta chain (By similarity).
SUBCELLULAR LOCATION: Plastid, chloroplast.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

AP006715; BAE92390.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

RefSeq

YP_536947.1; -.

3D structure databases

ModBase

Q1XDM1.

Family and domain databases

InterPro

IPR005476; Transketo_C.
IPR005475; Transketo_Cen_R.
IPR015941; Transketolase_C-like.
Graphical view of domain structure.

Gene3D

G3DSA:3.40.50.920; Transketo_C_like; 1.

Pfam

PF02779; Transket_pyr; 1.
PF02780; Transketolase_C; 1.
Pfam graphical view of domain structure.

BLOCKS

Q1XDM1.

Genome annotation databases

GeneID

3978894; -.

Other

ProtoNet

Q1XDM1.

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Chloroplast; Glycolysis; Oxidoreductase; Plastid; Pyruvate; Thiamine pyrophosphate.

Features

Feature table viewer

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 331`	`331`	`Pyruvate dehydrogenase E1 component subunit beta.`	`PRO_0000277254`
`BINDING`	`60 60`		`Thiamine pyrophosphate (By similarity).`

Sequence information

Length: 331 AA [This is the length of the unprocessed precursor]

Molecular weight: 36385 Da [This is the MW of the unprocessed precursor]

CRC64: 8F8C892E9684F733 [This is a checksum on the sequence]

        10         20         30         40         50         60 
MSKIFMFDAL RAATDEEMAK DPTVCVIGED VGHYGGSYKV TKDLHSKYGD LRVLDTPIAE 

        70         80         90        100        110        120 
NSFTGMAIGA AITGLRPIVE GMNMSFLLLA FNQISNNAGM LRYTSGGNFT LPLVIRGPGG 

       130        140        150        160        170        180 
VGRQLGAEHS QRLEAYFQAI PGLKIVACST PYNAKGLLKS AIRDNNPVVF FEHVLLYNLQ 

       190        200        210        220        230        240 
EEIPQEEYFL PLNKVEFVRK GKDITILTYS RMRHHVIQAL PALLKEGYDP EVIDLISLKP 

       250        260        270        280        290        300 
LDIDSISISV KKTHKVLIVE ECMKTAGIGA ELIAQINEYL FDELDAPVVR LSSQDIPTPY 

       310        320        330 
NGSLEQATVI QPSQIVDSVK SIITSVKAII T

Q1XDM1 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
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	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools