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UniProtKB/Swiss-Prot entry Q1MI52

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name HGD_RHIL3
Primary accession number Q1MI52
Secondary accession numbers None
Integrated into Swiss-Prot on January 15, 2008
Sequence was last modified on May 30, 2006 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 19)
Name and origin of the protein
Protein name Homogentisate 1,2-dioxygenase
Synonyms EC 1.13.11.5
Homogentisicase
Homogentisate oxygenase
Homogentisic acid oxidase
Gene name
Name: hmgA
OrderedLocusNames: RL1864
From
Rhizobium leguminosarum bv. viciae (strain 3841) [TaxID: 216596] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales; Rhizobiaceae; Rhizobium/Agrobacterium group; Rhizobium.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1186/gb-2006-7-4-r34; PubMed=16640791 [NCBI, ExPASy, EBI, Israel, Japan]
Young J.P.W., Crossman L.C., Johnston A.W.B., Thomson N.R., Ghazoui Z.F., Hull K.H., Wexler M., Curson A.R.J., Todd J.D., Poole P.S., Mauchline T.H., East A.K., Quail M.A., Churcher C., Arrowsmith C., Cherevach I., Chillingworth T., Clarke K., Cronin A., Davis P., Fraser A., Hance Z., Hauser H., Jagels K., Moule S., Mungall K., Norbertczak H., Rabbinowitsch E., Sanders M., Simmonds M., Whitehead S., Parkhill J.;
"The genome of Rhizobium leguminosarum has recognizable core and accessory components.";
Genome Biol. 7:RESEARCH34.1-RESEARCH34.20(2006).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AM236080; CAK07358.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_767467.1; -.
3D structure databases
ModBase Q1MI52.
Ontologies
GO
GO:0004411; Molecular function: homogentisate 1,2-dioxygenase activity (inferred from electronic annotation from HAMAP).
GO:0005506; Molecular function: iron ion binding (inferred from electronic annotation from HAMAP).
GO:0006559; Biological process: L-phenylalanine catabolic process (inferred from electronic annotation from HAMAP).
GO:0006572; Biological process: tyrosine catabolic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00334; -; 1.
PBIL [Tree]
InterPro IPR005708; Homogentis_dOase.
Graphical view of domain structure.
PANTHER PTHR11056; Homogentis_dOase; 1.
Pfam PF04209; HgmA; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR01015; hmgA; 1.
BLOCKS Q1MI52.
Genome annotation databases
GeneID 4402170; -.
GenomeReviews AM236080_GR; RL1864.
KEGG rle:RL1864; -.
NMPDR fig|216596.1.peg.1951; -.
Phylogenomic databases
HOGENOM Q1MI52; -.
Genome annotation databases
CMR Q1MI52; RL1864.
Other
ProtoNet Q1MI52.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Dioxygenase; Iron; Metal-binding; Oxidoreductase; Phenylalanine catabolism; Tyrosine catabolism.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   453  453     Homogentisate 1,2-dioxygenase. PRO_1000019539
METAL   349   349        Iron (By similarity). 
METAL   355   355        Iron (By similarity). 
METAL   385   385        Iron (By similarity). 
Sequence information
Length: 453 AA [This is the length of the unprocessed precursor] Molecular weight: 50888 Da [This is the MW of the unprocessed precursor] CRC64: F38F46C99C31976C [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MDQTSIQTSD GEAATANTLK YMPGFGNDFE TESLPGALPQ GQNSPQKCNY GLYAEQLSGS 

        70         80         90        100        110        120 
PFTAPRGTNE RSWLYRIRPS VRHTRRFSNA SYPLWKTAPC LDEHSLPLGQ LRWDPIPAPA 

       130        140        150        160        170        180 
ERLTFLEGVR TITTAGDAAT QVGMSAHAYV FNEDMVDDYF FNADGELLIV PQLGAIRVFT 

       190        200        210        220        230        240 
EMGIMDVEPL EICLIPRGMM FKILKSGEQT VWRGYICENY GAKFTLPDRG PIGANCLANP 

       250        260        270        280        290        300 
RDFKTPVAAF EDKETPCRVH VKWCGKFYVT EIGHSPLDVV AWHGNYAPFK YDLRTFSPVG 

       310        320        330        340        350        360 
AIRFDHPDPS IFSVLTAPSE DAGTANVDFV IFPPRWLVAE HTFRPPWYHR NIMSEFMGLI 

       370        380        390        400        410        420 
HGQYDAKEEG FVPGGISLHN MMLPHGPDAL AFEKASNTEL KPVKLDHTMA FMFETRYAQQ 

       430        440        450 
LTKYAAELET LQDNYLECWD GLERKFDGTP GIK
Q1MI52 in FASTA format

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