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UniProtKB/Swiss-Prot entry Q1GBV3


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name GUAC_LACDA
Primary accession number Q1GBV3
Secondary accession numbers None
Integrated into Swiss-Prot on July 10, 2007
Sequence was last modified on June 27, 2006 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 19)
Name and origin of the protein
Protein name GMP reductase
Synonyms EC 1.7.1.7
Guanosine 5'-monophosphate oxidoreductase
Guanosine monophosphate reductase
Gene name
Name: guaC
OrderedLocusNames: Ldb0292
From
Lactobacillus delbrueckii subsp. bulgaricus (strain ATCC 11842 / DSM 20081) [TaxID: 390333] [HAMAP proteome]
Taxonomy Bacteria; Firmicutes; Lactobacillales; Lactobacillaceae; Lactobacillus.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1073/pnas.0603024103; PubMed=16754859 [NCBI, ExPASy, EBI, Israel, Japan]
van de Guchte M., Penaud S., Grimaldi C., Barbe V., Bryson K., Nicolas P., Robert C., Oztas S., Mangenot S., Couloux A., Loux V., Dervyn R., Bossy R., Bolotin A., Batto J.-M., Walunas T., Gibrat J.-F., Bessieres P., Weissenbach J., Ehrlich S.D., Maguin E.;
"The complete genome sequence of Lactobacillus bulgaricus reveals extensive and ongoing reductive evolution.";
Proc. Natl. Acad. Sci. U.S.A. 103:9274-9279(2006).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CR954253; CAI97131.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_618437.1; -.
3D structure databases
ModBase Q1GBV3.
Enzyme and pathway databases
BioCyc LDEL390333:LDB0292-MON; -.
Ontologies
GO
GO:0003920; Molecular function: GMP reductase activity (inferred from electronic annotation from HAMAP).
GO:0006163; Biological process: purine nucleotide metabolic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_01511; -; 1.
PBIL [Tree]
InterPro IPR013785; Aldolase_TIM.
IPR005994; GMP_reduct2.
IPR015875; IMP_DH/GMP_Rdtase_CS.
IPR001093; IMP_DHase_GMPRtase.
Graphical view of domain structure.
Gene3D G3DSA:3.20.20.70; Aldolase_TIM; 1.
Pfam PF00478; IMPDH; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF036500; GMP_red_Firmic; 1.
TIGRFAMs TIGR01306; GMP_reduct_2; 1.
PROSITE PS00487; IMP_DH_GMP_RED; 1.
BLOCKS Q1GBV3.
Genome annotation databases
GeneID 4085331; -.
GenomeReviews CR954253_GR; Ldb0292.
KEGG ldb:Ldb0292; -.
Phylogenomic databases
HOGENOM Q1GBV3; -.
Genome annotation databases
CMR Q1GBV3; Ldb0292.
Other
ProtoNet Q1GBV3.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; NADP; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   330  330     GMP reductase. PRO_0000294273
NP_BIND   209   232  24     NADP (Potential). 
ACT_SITE   180   180        Thioimidate intermediate (By similarity). 
Sequence information
Length: 330 AA [This is the length of the unprocessed precursor] Molecular weight: 36703 Da [This is the MW of the unprocessed precursor] CRC64: 60A794BE7F9512BC [This is a checksum on the sequence]
        10         20         30         40         50         60 
MNNYFSMEAF DYDDIQLVPN KAIVKSRKEC VTSVKFGNRT FKIPVVPANM ESVIDEKLAV 

        70         80         90        100        110        120 
WLAQNGYYYV MHRFQPEKRA DFIKMMHEKG LFASISVGIK DDEYDFIDEL VEKDLIPEYT 

       130        140        150        160        170        180 
TIDVAHGHSV YVIDMIKYIK EKMPDTFLTA GNVATPEAVR ELENAGADAT KVGVGPGKAC 

       190        200        210        220        230        240 
ITKLKTGFGT GGWQLAALRM CSKVARKPLI ADGGIRHNGD IAKSVRFGAS MVMIGSMLAG 

       250        260        270        280        290        300 
HEESPGNVIK IDGKTYKQYW GSASEVQKGA YRNVEGKQML VPYRGSIANT LEEMKEDLQS 

       310        320        330 
SISYAGGRDL ESIKRVDYVI VKNTIMNGDY 

Q1GBV3 in FASTA format

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