ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!
Search for

UniProtKB/Swiss-Prot entry Q1E803


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

Note: most headings are clickable, even if they don't appear as links. They link to the user manual or other documents.
Entry information
Entry name HPPD_COCIM
Primary accession number Q1E803
Secondary accession numbers Q400Q2 Q9C0M8
Integrated into Swiss-Prot on October 3, 2006
Sequence was last modified on July 11, 2006 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 17)
Name and origin of the protein
Protein name 4-hydroxyphenylpyruvate dioxygenase
Synonyms HPPDase
4HPPD
HPD
EC 1.13.11.27
T-cell reactive protein
Gene name
Name: TCRP
ORFNames: CIMG_01310
From
Coccidioides immitis [TaxID: 5501] 
Taxonomy Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; Eurotiomycetidae; Onygenales; mitosporic Onygenales; Coccidioides.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=RS;
Birren B.W., Lander E.S., Galagan J.E., Devon K., Nusbaum C., Henn M., Ma L.-J., Jaffe D.B., Butler J., Alvarez P., Gnerre S., Grabherr M., Kleber M., Mauceli E.W., Brockman W., Rounsley S., Young S.K., LaButti K., Pushparaj V., DeCaprio D., Crawford M., Koehrsen M., Engels R., Montgomery P., Pearson M., Howarth C., Kodira C.D., Zeng Q., Yandava C., Alvarado L., Oleary S., Orbach M.J., Galgiani J., Mandel M.A., Kellner E.M.;
"Annotation of the Coccidioides immitis RS genome.";
Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
[2]
NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 233-362.
STRAIN=RMSCC 2267 / CA1;
DOI=10.1073/pnas.94.10.5478; PubMed=9144263 [NCBI, ExPASy, EBI, Israel, Japan]
Koufopanou V., Burt A., Taylor J.W.;
"Concordance of gene genealogies reveals reproductive isolation in the pathogenic fungus Coccidioides immitis.";
Proc. Natl. Acad. Sci. U.S.A. 94:5478-5482(1997).
[3]
ERRATUM.
Koufopanou V., Burt A., Taylor J.W.;
Proc. Natl. Acad. Sci. U.S.A. 95:8414-8414(1998).
[4]
NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 237-383.
STRAIN=IFM 45815, IFM 45816, IFM 46868, IFM 50992, and IFM 50995;
PubMed=16699492 [NCBI, ExPASy, EBI, Israel, Japan]
Sano A., Miyaji M., Kamei K., Mikami Y., Nishimura K.;
"Reexamination of Coccidioides spp. reserved in the Research Center for Pathogenic Fungi and Microbial Toxicoses, Chiba University, based on a multiple gene analysis.";
Nippon Ishinkin Gakkai Zasshi 47:113-117(2006).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CH476726; EAS35956.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AJ291969; CAC35134.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AB232871; BAE20316.1; ALT_SEQ; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AB232872; BAE20317.1; ALT_SEQ; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AB232874; BAE20319.1; ALT_SEQ; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AB232875; BAE20320.1; ALT_SEQ; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AB232878; BAE20323.1; ALT_SEQ; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq XP_001247539.1; -.
3D structure databases
ModBase Q1E803.
Family and domain databases
InterPro IPR005956; 4OHPhenylPyrv_dOase.
IPR004360; Glyas_bleo-R_dOase.
Graphical view of domain structure.
PANTHER PTHR11959; HPP_dOase; 1.
Pfam PF00903; Glyoxalase; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF009283; HPP_dOase; 1.
TIGRFAMs TIGR01263; 4HPPD; 1.
BLOCKS Q1E803.
Genome annotation databases
GeneID 4567103; -.
Other
ProtoNet Q1E803.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Dioxygenase; Iron; Metal-binding; Oxidoreductase; Phenylalanine catabolism; Tyrosine catabolism.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   399  399     4-hydroxyphenylpyruvate dioxygenase. PRO_0000252281
METAL   200   200        Iron (By similarity). 
METAL   283   283        Iron (By similarity). 
METAL   366   366        Iron (By similarity). 
Sequence information
Length: 399 AA [This is the length of the unprocessed precursor] Molecular weight: 45290 Da [This is the MW of the unprocessed precursor] CRC64: 7C440F0B51E82BA3 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MAPAADSPTL QPAQPSDLNQ YRGYDHVHWY VGNAKQAATY YVTRMGFERV AYRGLETGSK 

        70         80         90        100        110        120 
AVASHVVRNG NITFILTSPL RSVEQASRFP EDEALLKEIH AHLERHGDGV KDVAFEVDCV 

       130        140        150        160        170        180 
ESVFSAAVRN GAEVVSDVRT VEDEDGQIKM ATIRTYGETT HTLIERSGYR GGFMPGYRME 

       190        200        210        220        230        240 
SNVDATSKFL PKVVLERIDH CVGNQDWDEM ERVCDYYEKI LGFHRFWSVD DKDICTEFSA 

       250        260        270        280        290        300 
LKSIVMASPN DIVKMPINEP AKGKKQSQIE EYVDFYNGAG VQHIALRTNN IIDAITNLKA 

       310        320        330        340        350        360 
RGTEFIKVPE TYYEDMKIRL KRQGLVLDED FETLKSLDIL IDFDENGYLL QLFTKHLMDR 

       370        380        390 
PTVFIEIIQR NNFSGFGAGN FRALFEAIER EQALRGTLI 

Q1E803 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

BLAST logo BLAST submission on ExPASy/SIB
or at NCBI (USA)
Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
 Hosted by kr flag YPRC Korea Mirror sites: Australia  Brazil  Canada  China  Switzerland
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!