ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!
Search for

UniProtKB/Swiss-Prot entry Q1CGT4

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

Note: most headings are clickable, even if they don't appear as links. They link to the user manual or other documents.
Entry information
Entry name MAO1_YERPN
Primary accession number Q1CGT4
Secondary accession numbers None
Integrated into Swiss-Prot on February 5, 2008
Sequence was last modified on July 11, 2006 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 23)
Name and origin of the protein
Protein name NAD-dependent malic enzyme
Synonyms NAD-ME
EC 1.1.1.38
Gene name
Name: sfcA
OrderedLocusNames: YPN_2468
From
Yersinia pestis bv. Antiqua (strain Nepal516) [TaxID: 377628] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Yersinia.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1128/JB.00124-06; PubMed=16740952 [NCBI, ExPASy, EBI, Israel, Japan]
Chain P.S.G., Hu P., Malfatti S.A., Radnedge L., Larimer F., Vergez L.M., Worsham P., Chu M.C., Andersen G.L.;
"Complete genome sequence of Yersinia pestis strains Antiqua and Nepal516: evidence of gene reduction in an emerging pathogen.";
J. Bacteriol. 188:4453-4463(2006).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CP000305; ABG18796.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_648396.1; -.
3D structure databases
ModBase Q1CGT4.
Enzyme and pathway databases
BioCyc YPES377628:YPN_2468-MON; -.
Ontologies
GO
GO:0016619; Molecular function: malate dehydrogenase (oxaloacetate-decarboxylating) activity (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_01619; -; 1.
PBIL [Tree]
InterPro IPR015884; Malic_enzyme_CS.
IPR012301; Malic_N.
IPR012302; Malic_NAD_bd.
IPR001891; Malic_OxRdtase.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
Pfam PF00390; malic; 1.
PF03949; Malic_M; 1.
Pfam graphical view of domain structure.
PRINTS PR00072; MALOXRDTASE.
PROSITE PS00331; MALIC_ENZYMES; 1.
BLOCKS Q1CGT4.
Genome annotation databases
GeneID 4122790; -.
GenomeReviews CP000305_GR; YPN_2468.
KEGG ypn:YPN_2468; -.
Phylogenomic databases
HOGENOM Q1CGT4; -.
Genome annotation databases
CMR Q1CGT4; YPN_2468.
Other
ProtoNet Q1CGT4.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Metal-binding; NAD; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   565  565     NAD-dependent malic enzyme. PRO_1000069555
ACT_SITE   104   104        Proton donor (By similarity). 
ACT_SITE   175   175        Proton acceptor (By similarity). 
METAL   246   246        Divalent metal cation (By similarity). 
METAL   247   247        Divalent metal cation (By similarity). 
METAL   270   270        Divalent metal cation (By similarity). 
BINDING   157   157        NAD (By similarity). 
BINDING   270   270        NAD (By similarity). 
BINDING   418   418        NAD (By similarity). 
SITE   270   270  1     Important for activity (By similarity). 
Sequence information
Length: 565 AA [This is the length of the unprocessed precursor] Molecular weight: 62828 Da [This is the MW of the unprocessed precursor] CRC64: F57C1183EEC4AA3D [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MELEYESKRP LYIPYAGPIL LEFPLLNKGS AFTNDERNHF NLHGLLPEAV ETIEEQAERA 

        70         80         90        100        110        120 
YRQYQDFKND DDKHIYLRNI QDTNETLFYR LLEAHLSEMM PIIYTPTVGE ACEHFSDIYR 

       130        140        150        160        170        180 
RARGLFISYP NREHIDDMLQ NATKQNVKVI VVTDGERILG LGDQGIGGMG IPIGKLSLYT 

       190        200        210        220        230        240 
ACGGISPAYT LPVVLDVGTN NPQRLNDPLY MGWRHPRISG DEYYAFVDEF IQAVKRRWPN 

       250        260        270        280        290        300 
VLLQFEDFAQ KNATPLLNRY RDELCCFNDD IQGTAAVTLG SLIAASHAAG SQLRDQTVTF 

       310        320        330        340        350        360 
LGAGSAGCGI AEQIIAQMMS EGLSEIQARA RIFMVDRFGL LTDKLPNLLD FQSKLVQKSD 

       370        380        390        400        410        420 
DLHHWNLHND AISLLDVVRN AKPTVLIGVS GQPGLFTEEL IREMHSHCAR PIVMPLSNPT 

       430        440        450        460        470        480 
SRVEARPEDI INWTDGAALV ATGSPFPPVS YKEKLYPIAQ CNNSYIFPGI GLGVLASGAS 

       490        500        510        520        530        540 
RVTDGMLMAA SRALAESSPL ARHGEGALLP NIDDIQAVSK AIAMRVGQAA QLQGVAIVTS 

       550        560 
EEALSKAIEH NYWQPQYRSY KRTSF
Q1CGT4 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

BLAST logo BLAST submission on ExPASy/SIB
or at NCBI (USA) 		Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Hosted by kr flag YPRC Korea Mirror sites: Australia Brazil Canada China Switzerland
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!