NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1371/journal.pgen.0020120; PubMed=16789826 [NCBI, ExPASy, EBI, Israel, Japan]
Eppinger M., Baar C., Linz B., Raddatz G., Lanz C., Keller H., Morelli G., Gressmann H., Achtman M., Schuster S.C.;
"Who ate whom? Adaptive Helicobacter genomic changes that accompanied a host jump from early humans to large felines.";
PLoS Genet. 2:1097-1110(2006).

Comments

CATALYTIC ACTIVITY: (S)-malate + acceptor = oxaloacetate + reduced acceptor.
COFACTOR: FAD (By similarity).
PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle .
SIMILARITY: Belongs to the MQO family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

AM260522; CAK00239.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

RefSeq

YP_665238.1; -.

3D structure databases

ModBase

Q17VT7.

Enzyme and pathway databases

BioCyc

HACI382638:HAC_1519-MON; -.

Ontologies

GO:0008924;	Molecular function: malate dehydrogenase (acceptor) activity (inferred from electronic annotation from HAMAP).
GO:0006099;	Biological process: tricarboxylic acid cycle (inferred from electronic annotation from HAMAP).
QuickGo view.

Family and domain databases

HAMAP

MF_00212; -; 1.
PBIL [Tree]

InterPro

IPR006076; FAD-dep_OxRdtase.
Graphical view of domain structure.

Pfam

PF01266; DAO; 1.
Pfam graphical view of domain structure.

BLOCKS

Q17VT7.

Genome annotation databases

GeneID

4177339; -.

GenomeReviews

AM260522_GR; Hac_1519.

KEGG

hac:Hac_1519; -.

NMPDR

fig|382638.8.peg.1471; -.

Phylogenomic databases

HOGENOM

Q17VT7; -.

Genome annotation databases

CMR

Q17VT7; Hac_1519.

Other

ProtoNet

Q17VT7.

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Complete proteome; FAD; Flavoprotein; Oxidoreductase; Tricarboxylic acid cycle.

Features

Feature table viewer

`Key`	`From To`	`Length`		`Description`	`FTId`
`CHAIN`	`1 450`	`450`		`Probable malate:quinone oxidoreductase.`	`PRO_1000023805`

Sequence information

Length: 450 AA [This is the length of the unprocessed precursor]

Molecular weight: 50498 Da [This is the MW of the unprocessed precursor]

CRC64: 6AE69DBBDCF129E0 [This is a checksum on the sequence]

        10         20         30         40         50         60 
MSMEFDAVII GGGVSGCATF YTLSEYSSLK RVAIVEKCSK LAQISSSAKA NSQTIHDGSI 

        70         80         90        100        110        120 
ETNYTPEKAK KVRLSAYKTR QYALNKGLQN KAIFETQKMA IGVGDEECEF MKKRYESFKE 

       130        140        150        160        170        180 
IFVGLEEFDK QTIKELEPNV ILGASGIDRH ESIIGHGFRK DWSTMNYAKL SENFVEEALK 

       190        200        210        220        230        240 
LKPNNQVFLN FKVKKIEKRN DTYALISEDA EEVYAKFVLV NAGSYALPLA QSMGYGLDLG 

       250        260        270        280        290        300 
CLPVAGSFYF VPDLLKGKVY TVQNPKLPFA AVHGDPDAII KGKTRIGPTA LAMPKLERNK 

       310        320        330        340        350        360 
CWLKGISLEL LKMDLNKDVF KIAFDLMSDK EIRNYVLKNM VFELPVIGKR EFLKDAQKII 

       370        380        390        400        410        420 
PSLSLEDLEY AHGFGEVRPQ VLDKTKRKLE LGEKKICTHK GITFNMTPSP GATSCLQNAL 

       430        440        450 
VDSQEIVAYL GESFELERFY KDLSPEELES

Q17VT7 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
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	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools