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UniProtKB/Swiss-Prot entry Q13ZM3


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name PYRD_BURXL
Primary accession number Q13ZM3
Secondary accession numbers None
Integrated into Swiss-Prot on May 20, 2008
Sequence was last modified on May 20, 2008 (Sequence version 2)
Annotations were last modified on    July 22, 2008 (Entry version 21)
Name and origin of the protein
Protein name Dihydroorotate dehydrogenase
Synonyms EC 1.3.3.1
Dihydroorotate oxidase
DHOdehase
DHODase
DHOD
Gene name
Name: pyrD
OrderedLocusNames: Bxeno_A1928
ORFNames: Bxe_A2507
From
Burkholderia xenovorans (strain LB400) [TaxID: 266265] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales; Burkholderiaceae; Burkholderia.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1073/pnas.0606924103; PubMed=17030797 [NCBI, ExPASy, EBI, Israel, Japan]
Chain P.S.G., Denef V.J., Konstantinidis K.T., Vergez L.M., Agullo L., Reyes V.L., Hauser L., Cordova M., Gomez L., Gonzalez M., Land M., Lao V., Larimer F., LiPuma J.J., Mahenthiralingam E., Malfatti S.A., Marx C.J., Parnell J.J., Ramette A., Richardson P., Seeger M., Smith D., Spilker T., Sul W.J., Tsoi T.V., Ulrich L.E., Zhulin I.B., Tiedje J.M.;
"Burkholderia xenovorans LB400 harbors a multi-replicon, 9.73-Mbp genome shaped for versatility.";
Proc. Natl. Acad. Sci. U.S.A. 103:15280-15287(2006).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CP000270; ABE30466.1; ALT_INIT; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_558518.1; -.
3D structure databases
ModBase Q13ZM3.
Ontologies
GO
GO:0005886; Cellular component: plasma membrane (inferred from electronic annotation from HAMAP).
GO:0004158; Molecular function: dihydroorotate oxidase activity (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00225; -; 1.
PBIL [Tree]
InterPro IPR013785; Aldolase_TIM.
IPR012135; DHO_DHase_1_2.
IPR005719; DHO_DHase_2.
IPR001295; Dihydroorotate_DHase_core.
Graphical view of domain structure.
Gene3D G3DSA:3.20.20.70; Aldolase_TIM; 1.
Pfam PF01180; DHO_dh; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000164; DHO_oxidase; 1.
TIGRFAMs TIGR01036; pyrD_sub2; 1.
PROSITE PS00911; DHODEHASE_1; 1.
PS00912; DHODEHASE_2; 1.
BLOCKS Q13ZM3.
Genome annotation databases
GeneID 4004345; -.
GenomeReviews CP000270_GR; Bxeno_A1928.
KEGG bxe:Bxe_A2507; -.
Phylogenomic databases
HOGENOM Q13ZM3; -.
Genome annotation databases
CMR Q13ZM3; Bxeno_A1928.
Other
ProtoNet Q13ZM3.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Cell membrane; Complete proteome; Flavoprotein; FMN; Membrane; Oxidoreductase; Pyrimidine biosynthesis.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   340  340     Dihydroorotate dehydrogenase. PRO_0000336461
ACT_SITE   178   178        Nucleophile (By similarity). 
Sequence information
Length: 340 AA [This is the length of the unprocessed precursor] Molecular weight: 36285 Da [This is the MW of the unprocessed precursor] CRC64: 2B2D9D2478FBADBF [This is a checksum on the sequence]
        10         20         30         40         50         60 
MFSSLYPLVR AQLFRMDAED AHHLTLRILG AAGRTGLAGA LAPRVPDAPR TVMGLTFRNP 

        70         80         90        100        110        120 
VGLAAGLDKD GACIDGLAAL GFGFIEVGTV TPRAQPGNPR PRMFRLPQAN AVINRMGFNN 

       130        140        150        160        170        180 
AGVDQFVKNV QAARYRGILG LNIGKNADTP IERAAEDYLY CLDRVYPFAS YVTVNISSPN 

       190        200        210        220        230        240 
TKNLRQLQGA GELDALLAAL KDKQQRLADM HGKLVPLALK IAPDLDDEQI KSIADTLLRH 

       250        260        270        280        290        300 
RFEGVIATNT TLSRTAVAGM QYGDEAGGLS GKPVFDASNA VIRKLRAEVG ETVPIIGVGG 

       310        320        330        340 
IFSGEDARAK MAAGASLVQL YTGFIYRGPA LVAECVQALR 

Q13ZM3 in FASTA format

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BLAST logo BLAST submission on ExPASy/SIB
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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
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