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UniProtKB/Swiss-Prot entry Q13U85


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name PROA_BURXL
Primary accession number Q13U85
Secondary accession numbers None
Integrated into Swiss-Prot on October 17, 2006
Sequence was last modified on August 22, 2006 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 17)
Name and origin of the protein
Protein name Gamma-glutamyl phosphate reductase
Synonyms GPR
EC 1.2.1.41
Glutamate-5-semialdehyde dehydrogenase
Glutamyl-gamma-semialdehyde dehydrogenase
GSA dehydrogenase
Gene name
Name: proA
OrderedLocusNames: Bxeno_A3816
ORFNames: Bxe_A0579
From
Burkholderia xenovorans (strain LB400) [TaxID: 266265] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales; Burkholderiaceae; Burkholderia.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1073/pnas.0606924103; PubMed=17030797 [NCBI, ExPASy, EBI, Israel, Japan]
Chain P.S.G., Denef V.J., Konstantinidis K.T., Vergez L.M., Agullo L., Reyes V.L., Hauser L., Cordova M., Gomez L., Gonzalez M., Land M., Lao V., Larimer F., LiPuma J.J., Mahenthiralingam E., Malfatti S.A., Marx C.J., Parnell J.J., Ramette A., Richardson P., Seeger M., Smith D., Spilker T., Sul W.J., Tsoi T.V., Ulrich L.E., Zhulin I.B., Tiedje J.M.;
"Burkholderia xenovorans LB400 harbors a multi-replicon, 9.73-Mbp genome shaped for versatility.";
Proc. Natl. Acad. Sci. U.S.A. 103:15280-15287(2006).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CP000270; ABE32354.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_560406.1; -.
3D structure databases
ModBase Q13U85.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0004350; Molecular function: glutamate-5-semialdehyde dehydrogenase activity (inferred from electronic annotation from HAMAP).
GO:0006561; Biological process: proline biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00412; -; 1.
PBIL [Tree]
InterPro IPR016163; Ald_DHase_C.
IPR016162; Ald_DHase_N.
IPR015590; Aldehyde_DHase.
IPR000965; Gglut_pp_reduct.
IPR012134; Glu-5-SA_DHase.
Graphical view of domain structure.
Gene3D G3DSA:3.40.309.10; Aldehyde_dehydrogenase_C; 1.
G3DSA:3.40.605.10; Aldehyde_dehydrogenase_N; 1.
PANTHER PTHR11063:SF1; GSA_DH; 1.
Pfam PF00171; Aldedh; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000151; GPR; 1.
TIGRFAMs TIGR00407; proA; 1.
PROSITE PS01223; PROA; 1.
BLOCKS Q13U85.
Genome annotation databases
GeneID 4005832; -.
GenomeReviews CP000270_GR; Bxeno_A3816.
KEGG bxe:Bxe_A0579; -.
Phylogenomic databases
HOGENOM Q13U85; -.
Genome annotation databases
CMR Q13U85; Bxeno_A3816.
Other
ProtoNet Q13U85.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Amino-acid biosynthesis; Complete proteome; Cytoplasm; NADP; Oxidoreductase; Proline biosynthesis.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   423  423     Gamma-glutamyl phosphate reductase. PRO_0000252567
Sequence information
Length: 423 AA [This is the length of the unprocessed precursor] Molecular weight: 45304 Da [This is the MW of the unprocessed precursor] CRC64: 23BAD868B9656DF5 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MDIDQYMTDL GRRARQASRA MARASTAAKN AALAAVAEAI ERDAASLKEA NARDVAKARE 

        70         80         90        100        110        120 
KGHDAAFIDR LTLSDKALKT MVEGLRQVAA LADPIGEISN LKYRPSGIQV GQMRVPLGVI 

       130        140        150        160        170        180 
GIIYESRPNV TIDAAALCLK SGNATILRGG SEALECNTAL AKLIGEGLEA AGLPQDAVQV 

       190        200        210        220        230        240 
VATSDRAAVG KLITMTEYVD VIVPRGGKSL IERLMNEARV PMIKHLDGIC HVYVDDRADL 

       250        260        270        280        290        300 
TKALTVCDNA KTHRYGTCNT METLLVARGI AAEVLPPLGK LYRDKQVELR VDAAARAVLA 

       310        320        330        340        350        360 
DAGVGPLGDA TEEDWRTEYL APVLAIKVVD DLDAAIEHIN EYSSQHTDAI VTEDHDRAMR 

       370        380        390        400        410        420 
FLREVDSASV MVNASTRFAD GFEFGLGAEI GISNDKLHAR GPVGLEGLTS LKYVVLGHGE 


GRQ 

Q13U85 in FASTA format

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