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UniProtKB/Swiss-Prot entry Q13QH6


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name MHPE_BURXL
Primary accession number Q13QH6
Secondary accession numbers None
Integrated into Swiss-Prot on June 10, 2008
Sequence was last modified on August 22, 2006 (Sequence version 1)
Annotations were last modified on    September 2, 2008 (Entry version 18)
Name and origin of the protein
Protein name 4-hydroxy-2-oxovalerate aldolase
Synonyms HOA
EC 4.1.3.39
4-hydroxy-2-keto-pentanoic acid aldolase
Gene name
Name: mhpE
OrderedLocusNames: Bxeno_B0695
ORFNames: Bxe_B2325
From
Burkholderia xenovorans (strain LB400) [TaxID: 266265] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales; Burkholderiaceae; Burkholderia.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1073/pnas.0606924103; PubMed=17030797 [NCBI, ExPASy, EBI, Israel, Japan]
Chain P.S.G., Denef V.J., Konstantinidis K.T., Vergez L.M., Agullo L., Reyes V.L., Hauser L., Cordova M., Gomez L., Gonzalez M., Land M., Lao V., Larimer F., LiPuma J.J., Mahenthiralingam E., Malfatti S.A., Marx C.J., Parnell J.J., Ramette A., Richardson P., Seeger M., Smith D., Spilker T., Sul W.J., Tsoi T.V., Ulrich L.E., Zhulin I.B., Tiedje J.M.;
"Burkholderia xenovorans LB400 harbors a multi-replicon, 9.73-Mbp genome shaped for versatility.";
Proc. Natl. Acad. Sci. U.S.A. 103:15280-15287(2006).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CP000271; ABE33663.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_553013.1; -.
3D structure databases
SMR Q13QH6; 3-335.
ModBase Q13QH6.
Enzyme and pathway databases
BioCyc BXEN266265:BXE_B2325-MON; -.
Ontologies
GO
GO:0008701; Molecular function: 4-hydroxy-2-oxovalerate aldolase activity (inferred from electronic annotation from HAMAP).
GO:0019439; Biological process: aromatic compound catabolic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_01656; -; 1.
PBIL [Tree]
InterPro IPR017629; 4OH_2_O-val_aldolase.
IPR013785; Aldolase_TIM.
IPR012425; DmpG_comm.
IPR000891; PYR_CT.
Graphical view of domain structure.
Gene3D G3DSA:3.20.20.70; Aldolase_TIM; 1.
Pfam PF07836; DmpG_comm; 1.
PF00682; HMGL-like; 1.
Pfam graphical view of domain structure.
PROSITE PS50991; PYR_CT; 1.
PROSITE graphical view of domain structure (profiles).
Genome annotation databases
GeneID 4007179; -.
GenomeReviews CP000271_GR; Bxeno_B0695.
KEGG bxe:Bxe_B2325; -.
Phylogenomic databases
HOGENOM Q13QH6; -.
Genome annotation databases
CMR Q13QH6; Bxeno_B0695.
Other
ProtoNet Q13QH6.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Aromatic hydrocarbons catabolism; Complete proteome; Lyase.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   338  338     4-hydroxy-2-oxovalerate aldolase. PRO_0000337802
Sequence information
Length: 338 AA [This is the length of the unprocessed precursor] Molecular weight: 36450 Da [This is the MW of the unprocessed precursor] CRC64: 81AF29BB8BDD02EB [This is a checksum on the sequence]
        10         20         30         40         50         60 
MDRKLYISDV TLRDGSHAIR HQYSIDNVQQ IARALDSAKV DSIEVAHGDG LQGSSFNYGF 

        70         80         90        100        110        120 
GAHSDLEWIE AVADVVGHAQ IATLLLPGIG TIHDLKAAYQ AGARIVRVAT HCTEADISKQ 

       130        140        150        160        170        180 
HIEYARELGM DTVGFLMMSH MTTPENLAVE AKKMESYGAT CIYVVDSGGA MNMNDVRARF 

       190        200        210        220        230        240 
RALKAVLKPE TKTGMHAHHN LSLGVANSLV AVEEGCDRID ASLAGMGAGA GNAPLEVFIA 

       250        260        270        280        290        300 
AAERAGWHHG TDLYTLMDAA DDIVRPLQDR PVRVDRETLA LGYAGVYSSF LRHSEVAAKK 

       310        320        330 
YGLKAVDILV ELGKRRMVGG QEDMIVDVAL DLKRAAGV 

Q13QH6 in FASTA format

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BLAST logo BLAST submission on ExPASy/SIB
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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
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NPSA logo NPSA Sequence analysis tools

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