[1]
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NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM LONG), VARIANT PRO-679, AND TISSUE SPECIFICITY.
TISSUE=Fetal brain;
DOI=10.1006/geno.1996.0636; PubMed=8975710 [NCBI, ExPASy, EBI, Israel, Japan]
Song W.J.,
Sternberg L.R.,
Kasten-Sportes C.,
van Keuren M.L.,
Chung S.H.,
Slack A.C.,
Miller D.E.,
Glover T.W.,
Chiang P.W.,
Lou L.,
Kurnit D.W.;
"Isolation of human and murine homologues of the Drosophila minibrain gene: human homologue maps to 21q22.2 in the Down syndrome 'critical region'.";
Genomics 38:331-339(1996).
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[2]
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NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM LONG), TISSUE SPECIFICITY, AND POSSIBLE INVOLVEMENT IN DOWN SYNDROME.
DOI=10.1093/hmg/5.9.1305; PubMed=8872470 [NCBI, ExPASy, EBI, Israel, Japan]
Guimera J.,
Casas C.,
Pucharcos C.,
Solans A.,
Domenech A.,
Planas A.M.,
Ashley J.,
Lovett M.,
Estivill X.,
Pritchard M.A.;
"A human homologue of Drosophila minibrain (MNB) is expressed in the neuronal regions affected in Down syndrome and maps to the critical region.";
Hum. Mol. Genet. 5:1305-1310(1996).
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[3]
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NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), FUNCTION, TISSUE SPECIFICITY, AND DEVELOPMENTAL STAGE.
TISSUE=Fetal brain;
DOI=10.1006/bbrc.1996.1135; PubMed=8769099 [NCBI, ExPASy, EBI, Israel, Japan]
Shindoh N.,
Kudoh J.,
Maeda H.,
Yamaki A.,
Minoshima S.,
Shimizu Y.,
Shimizu N.;
"Cloning of a human homolog of the Drosophila minibrain/rat Dyrk gene from 'the Down syndrome critical region' of chromosome 21.";
Biochem. Biophys. Res. Commun. 225:92-99(1996).
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[4]
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NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
TISSUE=Promyelocytic leukemia;
PubMed=9037601 [NCBI, ExPASy, EBI, Israel, Japan]
Ohira M.,
Seki N.,
Nagase T.,
Suzuki E.,
Nomura N.,
Ohara O.,
Hattori M.,
Sakaki Y.,
Eki T.,
Murakami Y.,
Saito T.,
Ichikawa H.,
Ohki M.;
"Gene identification in 1.6-Mb region of the Down syndrome region on chromosome 21.";
Genome Res. 7:47-58(1997).
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[5]
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NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 4), TISSUE SPECIFICITY, POSSIBLE INVOLVEMENT IN DOWN SYNDROME, VARIANTS PHE-415 AND HIS-681, AND ALTERNATIVE SPLICING.
DOI=10.1006/geno.1999.5775; PubMed=10329007 [NCBI, ExPASy, EBI, Israel, Japan]
Guimera J.,
Casas C.,
Estivill X.,
Pritchard M.A.;
"Human minibrain homologue (MNBH/DYRK1): characterization, alternative splicing, differential tissue expression, and overexpression in Down syndrome.";
Genomics 57:407-418(1999).
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[6]
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NUCLEOTIDE SEQUENCE [MRNA] OF 234-380.
TISSUE=Fetal brain;
DOI=10.1006/geno.1997.5146; PubMed=9503011 [NCBI, ExPASy, EBI, Israel, Japan]
Dahmane N.,
Ait Ghezala G.,
Gosset P.,
Chamoun Z.,
Dufresne-Zacharia M.-C.,
Lopes C.,
Rabatel N.,
Gassanova-Maugenre S.,
Chettouh Z.,
Abramowski V.,
Fayet E.,
Yaspo M.-L.,
Korn B.,
Blouin J.-L.,
Lehrach H.,
Poustka A.,
Antonarakis S.E.,
Sinet P.-M.,
Creau N.,
Delabar J.-M.;
"Transcriptional map of the 2.5-Mb CBR-ERG region of chromosome 21 involved in Down syndrome.";
Genomics 48:12-23(1998).
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[7]
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INTERACTION WITH RANBP9, AND ENZYME REGULATION.
DOI=10.1074/jbc.M307556200; PubMed=14500717 [NCBI, ExPASy, EBI, Israel, Japan]
Zou Y.,
Lim S.,
Lee K.,
Deng X.,
Friedman E.;
"Serine/threonine kinase Mirk/Dyrk1B is an inhibitor of epithelial cell migration and is negatively regulated by the Met adaptor Ran-binding protein M.";
J. Biol. Chem. 278:49573-49581(2003).
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[8]
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PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-145 AND TYR-321, AND MASS SPECTROMETRY.
DOI=10.1038/nbt1046; PubMed=15592455 [NCBI, ExPASy, EBI, Israel, Japan]
Rush J.,
Moritz A.,
Lee K.A.,
Guo A.,
Goss V.L.,
Spek E.J.,
Zhang H.,
Zha X.-M.,
Polakiewicz R.D.,
Comb M.J.;
"Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.";
Nat. Biotechnol. 23:94-101(2005).
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[9]
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PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-145, AND MASS SPECTROMETRY.
DOI=10.1016/j.cell.2007.11.025; PubMed=18083107 [NCBI, ExPASy, EBI, Israel, Japan]
Rikova K.,
Guo A.,
Zeng Q.,
Possemato A.,
Yu J.,
Haack H.,
Nardone J.,
Lee K.,
Reeves C.,
Li Y.,
Hu Y.,
Tan Z.,
Stokes M.,
Sullivan L.,
Mitchell J.,
Wetzel R.,
Macneill J.,
Ren J.M.,
Yuan J., ![]()
Bakalarski C.E.,
Villen J.,
Kornhauser J.M.,
Smith B.,
Li D.,
Zhou X.,
Gygi S.P.,
Gu T.-L.,
Polakiewicz R.D.,
Rush J.,
Comb M.J.;
"Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer.";
Cell 131:1190-1203(2007).
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[10]
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PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-321, AND MASS SPECTROMETRY.
DOI=10.1074/mcp.T600062-MCP200; PubMed=17192257 [NCBI, ExPASy, EBI, Israel, Japan]
Wissing J.,
Jaensch L.,
Nimtz M.,
Dieterich G.,
Hornberger R.,
Keri G.,
Wehland J.,
Daub H.;
"Proteomics analysis of protein kinases by target class-selective prefractionation and tandem mass spectrometry.";
Mol. Cell. Proteomics 6:537-547(2007).
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[11]
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PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-321, AND MASS SPECTROMETRY.
TISSUE=Platelet;
DOI=10.1021/pr0704130; PubMed=18088087 [NCBI, ExPASy, EBI, Israel, Japan]
Zahedi R.P.,
Lewandrowski U.,
Wiesner J.,
Wortelkamp S.,
Moebius J.,
Schuetz C.,
Walter U.,
Gambaryan S.,
Sickmann A.;
"Phosphoproteome of resting human platelets.";
J. Proteome Res. 7:526-534(2008).
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[12]
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PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-321; SER-748 AND SER-758, AND MASS SPECTROMETRY.
DOI=10.1016/j.molcel.2008.07.007; PubMed=18691976 [NCBI, ExPASy, EBI, Israel, Japan]
Daub H.,
Olsen J.V.,
Bairlein M.,
Gnad F.,
Oppermann F.S.,
Korner R.,
Greff Z.,
Keri G.,
Stemmann O.,
Mann M.;
"Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.";
Mol. Cell 31:438-448(2008).
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[13]
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VARIANT [LARGE SCALE ANALYSIS] PRO-679.
DOI=10.1038/nature05610; PubMed=17344846 [NCBI, ExPASy, EBI, Israel, Japan]
Greenman C.,
Stephens P.,
Smith R.,
Dalgliesh G.L.,
Hunter C.,
Bignell G.,
Davies H.,
Teague J.,
Butler A.,
Stevens C.,
Edkins S.,
O'Meara S.,
Vastrik I.,
Schmidt E.E.,
Avis T.,
Barthorpe S.,
Bhamra G.,
Buck G.,
Choudhury B., ![]()
Clements J.,
Cole J.,
Dicks E.,
Forbes S.,
Gray K.,
Halliday K.,
Harrison R.,
Hills K.,
Hinton J.,
Jenkinson A.,
Jones D.,
Menzies A.,
Mironenko T.,
Perry J.,
Raine K.,
Richardson D.,
Shepherd R.,
Small A.,
Tofts C.,
Varian J.,
Webb T.,
West S.,
Widaa S.,
Yates A.,
Cahill D.P.,
Louis D.N.,
Goldstraw P.,
Nicholson A.G.,
Brasseur F.,
Looijenga L.,
Weber B.L.,
Chiew Y.-E.,
DeFazio A.,
Greaves M.F.,
Green A.R.,
Campbell P.,
Birney E.,
Easton D.F.,
Chenevix-Trench G.,
Tan M.-H.,
Khoo S.K.,
Teh B.T.,
Yuen S.T.,
Leung S.Y.,
Wooster R.,
Futreal P.A.,
Stratton M.R.;
"Patterns of somatic mutation in human cancer genomes.";
Nature 446:153-158(2007).
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