ID   ACSF_RHOPS              Reviewed;         367 AA.
AC   Q132P2;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   31-OCT-2006, sequence version 1.
DT   04-NOV-2008, entry version 17.
DE   RecName: Full=Aerobic magnesium-protoporphyrin IX monomethyl ester [oxidative] cyclase;
DE            Short=Aerobic Mg-protoporphyrin IX monomethyl ester oxidative cyclase;
DE            EC=1.14.13.81;
GN   Name=acsF; OrderedLocusNames=RPD_3726;
OS   Rhodopseudomonas palustris (strain BisB5).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Bradyrhizobiaceae; Rhodopseudomonas.
OX   NCBI_TaxID=316057;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H.,
RA   Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J.,
RA   Larimer F., Land M., Hauser L., Pelletier D.A., Kyrpides N.,
RA   Lykidis A., Oda Y., Harwood C.S., Richardson P.;
RT   "Complete sequence of Rhodopseudomonas palustris BisB5.";
RL   Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Catalyzes the formation of the isocyclic ring in
CC       chlorophyll biosynthesis. Mediates the cyclase reaction, which
CC       results in the formation of divinylprotochlorophyllide (Pchlide)
CC       characteristic of all chlorophylls from magnesium-protoporphyrin
CC       IX 13-monomethyl ester (MgPMME) (By similarity).
CC   -!- CATALYTIC ACTIVITY: Magnesium-protoporphyrin IX 13-monomethyl
CC       ester + NADPH + O(2) = 13(1)-hydroxy-magnesium-protoporphyrin IX
CC       13-monomethyl ester + NADP(+) + H(2)O.
CC   -!- CATALYTIC ACTIVITY: 13(1)-hydroxy-magnesium-protoporphyrin IX 13-
CC       monomethyl ester + NADPH + O(2) = 13(1)-oxo-magnesium-
CC       protoporphyrin IX 13-monomethyl ester + NADP(+) + 2 H(2)O.
CC   -!- CATALYTIC ACTIVITY: 13(1)-oxo-magnesium-protoporphyrin IX 13-
CC       monomethyl ester + NADPH + O(2) = divinylprotochlorophyllide +
CC       NADP(+) + 2 H(2)O.
CC   -!- COFACTOR: Iron (By similarity).
CC   -!- PATHWAY: Porphyrin biosynthesis; bacteriochlorophyll biosynthesis
CC       (light-independent).
CC   -!- SIMILARITY: Belongs to the acsF family.
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DR   EMBL; CP000283; ABE40947.1; -; Genomic_DNA.
DR   RefSeq; YP_570848.1; -.
DR   GeneID; 4024242; -.
DR   GenomeReviews; CP000283_GR; RPD_3726.
DR   KEGG; rpd:RPD_3726; -.
DR   HOGENOM; Q132P2; -.
DR   BioCyc; RPAL316057:RPD_3726-MON; -.
DR   GO; GO:0005506; F:iron ion binding; IEA:HAMAP.
DR   GO; GO:0048529; F:magnesium-protoporphyrin IX monomethyl este...; IEA:HAMAP.
DR   GO; GO:0030494; P:bacteriochlorophyll biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW.
DR   GO; GO:0015979; P:photosynthesis; IEA:HAMAP.
DR   HAMAP; MF_01840; -; 1.
DR   InterPro; IPR008434; AcsF.
DR   InterPro; IPR012347; Ferritin_rel.
DR   InterPro; IPR003251; Rubrerythrin.
DR   Gene3D; G3DSA:1.20.1260.10; Ferritin_rel; 1.
DR   Pfam; PF02915; Rubrerythrin; 1.
DR   TIGRFAMs; TIGR02029; AcsF; 1.
PE   3: Inferred from homology;
KW   Bacteriochlorophyll biosynthesis; Chlorophyll biosynthesis;
KW   Complete proteome; Iron; Metal-binding; NADP; Oxidoreductase;
KW   Photosynthesis.
FT   CHAIN         1    367       Aerobic magnesium-protoporphyrin IX
FT                                monomethyl ester [oxidative] cyclase.
FT                                /FTId=PRO_1000070551.
SQ   SEQUENCE   367 AA;  42709 MW;  67A5DB88D338C05E CRC64;
     MIPMEGGAQG ALRTNSRPAI KGSVDSLNIA KEDTILTPRF YTTDYAAMDK LDVSLVRSEW
     NAMMNEMRAD YNKAHFKKTD EFLESDLDKL PPELLIEFKD FLVSSLTAEF SGCVLYSEIK
     KRIKNPEIRE LFGLLSRDEA RHAGFINEIL KDHGIGVDLS FLTKVKKYTY FRPKFIFYAT
     YLSEKIGYAR YITIYRQMER HPERRFHPIF KWFERWCNDE FRHGEAFALL MRADPSLLRG
     VNKLWIRFFL LAVFATMYVR DHMRPAFYDA LGVDATDYDM QVFRVTTEIS KQVFPVMINL
     DDPRFLAGLE RLRKVSEKIA ESRSQGFVGK LKRPLYAASA AIAFGRLFLL PAKRNELPRV
     IGLRPAW
//