[1]
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NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
TISSUE=Mammary gland;
Yano K.;
"Nucleotide sequence of cDNA for human AMP-activated protein kinase alpha-1.";
Submitted (JAN-1999) to the EMBL/GenBank/DDBJ databases.
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[2]
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NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
TISSUE=Umbilical cord blood;
DOI=10.1101/gr.140200; PubMed=11042152 [NCBI, ExPASy, EBI, Israel, Japan]
Zhang Q.-H.,
Ye M.,
Wu X.-Y.,
Ren S.-X.,
Zhao M.,
Zhao C.-J.,
Fu G.,
Shen Y.,
Fan H.-Y.,
Lu G.,
Zhong M.,
Xu X.-R.,
Han Z.-G.,
Zhang J.-W.,
Tao J.,
Huang Q.-H.,
Zhou J.,
Hu G.-X.,
Gu J., ![]()
Chen S.-J.,
Chen Z.;
"Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells.";
Genome Res. 10:1546-1560(2000).
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[3]
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NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
TISSUE=Trachea;
DOI=10.1038/ng1285; PubMed=14702039 [NCBI, ExPASy, EBI, Israel, Japan]
Ota T.,
Suzuki Y.,
Nishikawa T.,
Otsuki T.,
Sugiyama T.,
Irie R.,
Wakamatsu A.,
Hayashi K.,
Sato H.,
Nagai K.,
Kimura K.,
Makita H.,
Sekine M.,
Obayashi M.,
Nishi T.,
Shibahara T.,
Tanaka T.,
Ishii S.,
Yamamoto J., ![]()
Saito K.,
Kawai Y.,
Isono Y.,
Nakamura Y.,
Nagahari K.,
Murakami K.,
Yasuda T.,
Iwayanagi T.,
Wagatsuma M.,
Shiratori A.,
Sudo H.,
Hosoiri T.,
Kaku Y.,
Kodaira H.,
Kondo H.,
Sugawara M.,
Takahashi M.,
Kanda K.,
Yokoi T.,
Furuya T.,
Kikkawa E.,
Omura Y.,
Abe K.,
Kamihara K.,
Katsuta N.,
Sato K.,
Tanikawa M.,
Yamazaki M.,
Ninomiya K.,
Ishibashi T.,
Yamashita H.,
Murakawa K.,
Fujimori K.,
Tanai H.,
Kimata M.,
Watanabe M.,
Hiraoka S.,
Chiba Y.,
Ishida S.,
Ono Y.,
Takiguchi S.,
Watanabe S.,
Yosida M.,
Hotuta T.,
Kusano J.,
Kanehori K.,
Takahashi-Fujii A.,
Hara H.,
Tanase T.-O.,
Nomura Y.,
Togiya S.,
Komai F.,
Hara R.,
Takeuchi K.,
Arita M.,
Imose N.,
Musashino K.,
Yuuki H.,
Oshima A.,
Sasaki N.,
Aotsuka S.,
Yoshikawa Y.,
Matsunawa H.,
Ichihara T.,
Shiohata N.,
Sano S.,
Moriya S.,
Momiyama H.,
Satoh N.,
Takami S.,
Terashima Y.,
Suzuki O.,
Nakagawa S.,
Senoh A.,
Mizoguchi H.,
Goto Y.,
Shimizu F.,
Wakebe H.,
Hishigaki H.,
Watanabe T.,
Sugiyama A.,
Takemoto M.,
Kawakami B.,
Yamazaki M.,
Watanabe K.,
Kumagai A.,
Itakura S.,
Fukuzumi Y.,
Fujimori Y.,
Komiyama M.,
Tashiro H.,
Tanigami A.,
Fujiwara T.,
Ono T.,
Yamada K.,
Fujii Y.,
Ozaki K.,
Hirao M.,
Ohmori Y.,
Kawabata A.,
Hikiji T.,
Kobatake N.,
Inagaki H.,
Ikema Y.,
Okamoto S.,
Okitani R.,
Kawakami T.,
Noguchi S.,
Itoh T.,
Shigeta K.,
Senba T.,
Matsumura K.,
Nakajima Y.,
Mizuno T.,
Morinaga M.,
Sasaki M.,
Togashi T.,
Oyama M.,
Hata H.,
Watanabe M.,
Komatsu T.,
Mizushima-Sugano J.,
Satoh T.,
Shirai Y.,
Takahashi Y.,
Nakagawa K.,
Okumura K.,
Nagase T.,
Nomura N.,
Kikuchi H.,
Masuho Y.,
Yamashita R.,
Nakai K.,
Yada T.,
Nakamura Y.,
Ohara O.,
Isogai T.,
Sugano S.;
"Complete sequencing and characterization of 21,243 full-length human cDNAs.";
Nat. Genet. 36:40-45(2004).
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[4]
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NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1038/nature02919; PubMed=15372022 [NCBI, ExPASy, EBI, Israel, Japan]
Schmutz J.,
Martin J.,
Terry A.,
Couronne O.,
Grimwood J.,
Lowry S.,
Gordon L.A.,
Scott D.,
Xie G.,
Huang W.,
Hellsten U.,
Tran-Gyamfi M.,
She X.,
Prabhakar S.,
Aerts A.,
Altherr M.,
Bajorek E.,
Black S.,
Branscomb E., ![]()
Caoile C.,
Challacombe J.F.,
Chan Y.M.,
Denys M.,
Detter J.C.,
Escobar J.,
Flowers D.,
Fotopulos D.,
Glavina T.,
Gomez M.,
Gonzales E.,
Goodstein D.,
Grigoriev I.,
Groza M.,
Hammon N.,
Hawkins T.,
Haydu L.,
Israni S.,
Jett J.,
Kadner K.,
Kimball H.,
Kobayashi A.,
Lopez F.,
Lou Y.,
Martinez D.,
Medina C.,
Morgan J.,
Nandkeshwar R.,
Noonan J.P.,
Pitluck S.,
Pollard M.,
Predki P.,
Priest J.,
Ramirez L.,
Retterer J.,
Rodriguez A.,
Rogers S.,
Salamov A.,
Salazar A.,
Thayer N.,
Tice H.,
Tsai M.,
Ustaszewska A.,
Vo N.,
Wheeler J.,
Wu K.,
Yang J.,
Dickson M.,
Cheng J.-F.,
Eichler E.E.,
Olsen A.,
Pennacchio L.A.,
Rokhsar D.S.,
Richardson P.,
Lucas S.M.,
Myers R.M.,
Rubin E.M.;
"The DNA sequence and comparative analysis of human chromosome 5.";
Nature 431:268-274(2004).
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[5]
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NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
TISSUE=Brain, and Testis;
DOI=10.1101/gr.2596504; PubMed=15489334 [NCBI, ExPASy, EBI, Israel, Japan]
The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
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[6]
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NUCLEOTIDE SEQUENCE [MRNA] OF 27-200 (ISOFORM 1).
TISSUE=Intestine;
Taboada E.N.,
Hickey D.A.;
Submitted (APR-1995) to the EMBL/GenBank/DDBJ databases.
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[7]
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NUCLEOTIDE SEQUENCE [MRNA] OF 294-550 (ISOFORM 1/2).
TISSUE=Liver;
DOI=10.1074/jbc.271.2.611; PubMed=8557660 [NCBI, ExPASy, EBI, Israel, Japan]
Stapleton D.,
Mitchelhill K.I.,
Gao G.,
Widmer J.,
Michell B.J.,
Teh T.,
House C.M.,
Fernandez C.S.,
Cox T.,
Witters L.A.,
Kemp B.E.;
"Mammalian AMP-activated protein kinase subfamily.";
J. Biol. Chem. 271:611-614(1996).
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[8]
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FUNCTION, AND ENZYME REGULATION.
DOI=10.1038/sj.emboj.7600110; PubMed=14976552 [NCBI, ExPASy, EBI, Israel, Japan]
Lizcano J.M.,
Goeransson O.,
Toth R.,
Deak M.,
Morrice N.A.,
Boudeau J.,
Hawley S.A.,
Udd L.,
Maekelae T.P.,
Hardie D.G.,
Alessi D.R.;
"LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1.";
EMBO J. 23:833-843(2004).
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[9]
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FUNCTION, AND ENZYME REGULATION.
DOI=10.1016/j.cmet.2005.05.009; PubMed=16054095 [NCBI, ExPASy, EBI, Israel, Japan]
Hawley S.A.,
Pan D.A.,
Mustard K.J.,
Ross L.,
Bain J.,
Edelman A.M.,
Frenguelli B.G.,
Hardie D.G.;
"Calmodulin-dependent protein kinase kinase-beta is an alternative upstream kinase for AMP-activated protein kinase.";
Cell Metab. 2:9-19(2005).
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[10]
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PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-487, AND MASS SPECTROMETRY.
DOI=10.1021/pr050048h; PubMed=16083285 [NCBI, ExPASy, EBI, Israel, Japan]
Kim J.-E.,
Tannenbaum S.R.,
White F.M.;
"Global phosphoproteome of HT-29 human colon adenocarcinoma cells.";
J. Proteome Res. 4:1339-1346(2005).
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[11]
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PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-433, AND MASS SPECTROMETRY.
DOI=10.1016/j.cell.2007.11.025; PubMed=18083107 [NCBI, ExPASy, EBI, Israel, Japan]
Rikova K.,
Guo A.,
Zeng Q.,
Possemato A.,
Yu J.,
Haack H.,
Nardone J.,
Lee K.,
Reeves C.,
Li Y.,
Hu Y.,
Tan Z.,
Stokes M.,
Sullivan L.,
Mitchell J.,
Wetzel R.,
Macneill J.,
Ren J.M.,
Yuan J., ![]()
Bakalarski C.E.,
Villen J.,
Kornhauser J.M.,
Smith B.,
Li D.,
Zhou X.,
Gygi S.P.,
Gu T.-L.,
Polakiewicz R.D.,
Rush J.,
Comb M.J.;
"Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer.";
Cell 131:1190-1203(2007).
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[12]
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PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-487, AND MASS SPECTROMETRY.
TISSUE=Platelet;
DOI=10.1021/pr0704130; PubMed=18088087 [NCBI, ExPASy, EBI, Israel, Japan]
Zahedi R.P.,
Lewandrowski U.,
Wiesner J.,
Wortelkamp S.,
Moebius J.,
Schuetz C.,
Walter U.,
Gambaryan S.,
Sickmann A.;
"Phosphoproteome of resting human platelets.";
J. Proteome Res. 7:526-534(2008).
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[13]
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PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-373, AND MASS SPECTROMETRY.
DOI=10.1021/pr0705441; PubMed=18220336 [NCBI, ExPASy, EBI, Israel, Japan]
Cantin G.T.,
Yi W.,
Lu B.,
Park S.K.,
Xu T.,
Lee J.-D.,
Yates J.R. III;
"Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis.";
J. Proteome Res. 7:1346-1351(2008).
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[14]
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INTERACTION WITH FNIP1.
DOI=10.1073/pnas.0603781103; PubMed=17028174 [NCBI, ExPASy, EBI, Israel, Japan]
Baba M.,
Hong S.-B.,
Sharma N.,
Warren M.B.,
Nickerson M.L.,
Iwamatsu A.,
Esposito D.,
Gillette W.K.,
Hopkins R.F. III,
Hartley J.L.,
Furihata M.,
Oishi S.,
Zhen W.,
Burke T.R. Jr.,
Linehan W.M.,
Schmidt L.S.,
Zbar B.;
"Folliculin encoded by the BHD gene interacts with a binding protein, FNIP1, and AMPK, and is involved in AMPK and mTOR signaling.";
Proc. Natl. Acad. Sci. U.S.A. 103:15552-15557(2006).
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[15]
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INTERACTION WITH FNIP2.
DOI=10.1016/j.gene.2008.02.022; PubMed=18403135 [NCBI, ExPASy, EBI, Israel, Japan]
Hasumi H.,
Baba M.,
Hong S.-B.,
Hasumi Y.,
Huang Y.,
Yao M.,
Valera V.A.,
Linehan W.M.,
Schmidt L.S.;
"Identification and characterization of a novel folliculin-interacting protein FNIP2.";
Gene 415:60-67(2008).
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[16]
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PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-347; SER-477; THR-481; SER-487; SER-499; SER-514 AND SER-518, AND MASS SPECTROMETRY.
DOI=10.1016/j.molcel.2008.07.007; PubMed=18691976 [NCBI, ExPASy, EBI, Israel, Japan]
Daub H.,
Olsen J.V.,
Bairlein M.,
Gnad F.,
Oppermann F.S.,
Korner R.,
Greff Z.,
Keri G.,
Stemmann O.,
Mann M.;
"Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.";
Mol. Cell 31:438-448(2008).
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[17]
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PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-347; THR-373; SER-477; THR-481 AND SER-487, AND MASS SPECTROMETRY.
DOI=10.1073/pnas.0805139105; PubMed=18669648 [NCBI, ExPASy, EBI, Israel, Japan]
Dephoure N.,
Zhou C.,
Villen J.,
Beausoleil S.A.,
Bakalarski C.E.,
Elledge S.J.,
Gygi S.P.;
"A quantitative atlas of mitotic phosphorylation.";
Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
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[18]
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VARIANT [LARGE SCALE ANALYSIS] ARG-7.
DOI=10.1126/science.1133427; PubMed=16959974 [NCBI, ExPASy, EBI, Israel, Japan]
Sjoeblom T.,
Jones S.,
Wood L.D.,
Parsons D.W.,
Lin J.,
Barber T.D.,
Mandelker D.,
Leary R.J.,
Ptak J.,
Silliman N.,
Szabo S.,
Buckhaults P.,
Farrell C.,
Meeh P.,
Markowitz S.D.,
Willis J.,
Dawson D.,
Willson J.K.V.,
Gazdar A.F., ![]()
Hartigan J.,
Wu L.,
Liu C.,
Parmigiani G.,
Park B.H.,
Bachman K.E.,
Papadopoulos N.,
Vogelstein B.,
Kinzler K.W.,
Velculescu V.E.;
"The consensus coding sequences of human breast and colorectal cancers.";
Science 314:268-274(2006).
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