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UniProtKB/Swiss-Prot entry Q12X08

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name DNLI_METBU
Primary accession number Q12X08
Secondary accession numbers None
Integrated into Swiss-Prot on January 15, 2008
Sequence was last modified on August 22, 2006 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 21)
Name and origin of the protein
Protein name DNA ligase
Synonyms EC 6.5.1.1
Polydeoxyribonucleotide synthase [ATP]
Gene name
Name: lig
OrderedLocusNames: Mbur_1088
From
Methanococcoides burtonii (strain DSM 6242) [TaxID: 259564] [HAMAP proteome]
Taxonomy Archaea; Euryarchaeota; Methanomicrobia; Methanosarcinales; Methanosarcinaceae; Methanococcoides.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Kadner K., Aerts A., Dehal P., Pitluck S., Martinez M., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Anderson I., Franzmann P., Thomas T., Saunders N., Cavicchioli R., Sowers K., Richardson P.;
"Complete sequence of Methanococcoides burtonii DSM 6242.";
Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases.
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CP000300; ABE52018.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_565768.1; -.
3D structure databases
ModBase Q12X08.
Enzyme and pathway databases
BioCyc MBUR259564:MBUR_1088-MON; -.
Ontologies
GO
GO:0005524; Molecular function: ATP binding (inferred from electronic annotation from HAMAP).
GO:0003677; Molecular function: DNA binding (inferred from electronic annotation from InterPro).
GO:0003910; Molecular function: DNA ligase (ATP) activity (inferred from electronic annotation from HAMAP).
GO:0007049; Biological process: cell cycle (inferred from electronic annotation from UniProtKB-KW).
GO:0051301; Biological process: cell division (inferred from electronic annotation from UniProtKB-KW).
GO:0006310; Biological process: DNA recombination (inferred from electronic annotation from HAMAP).
GO:0006281; Biological process: DNA repair (inferred from electronic annotation from HAMAP).
GO:0006260; Biological process: DNA replication (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00407; -; 1.
PBIL [Tree]
InterPro IPR000977; DNA_ligase.
IPR012309; DNA_ligase_A_C.
IPR012310; DNA_ligase_A_M.
IPR012308; DNA_ligase_A_N.
IPR016059; DNA_ligase_CS.
IPR012340; NA-bd_OB-fold.
Graphical view of domain structure.
Gene3D G3DSA:2.40.50.140; OB_NA_bd_sub; 1.
Pfam PF04679; DNA_ligase_A_C; 1.
PF01068; DNA_ligase_A_M; 1.
PF04675; DNA_ligase_A_N; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR00574; dnl1; 1.
PROSITE PS00697; DNA_LIGASE_A1; 1.
PS00333; DNA_LIGASE_A2; FALSE_NEG.
PS50160; DNA_LIGASE_A3; 1.
PROSITE graphical view of domain structure (profiles).
Genome annotation databases
GeneID 3998025; -.
GenomeReviews CP000300_GR; Mbur_1088.
KEGG mbu:Mbur_1088; -.
NMPDR fig|259564.8.peg.1034; -.
Phylogenomic databases
HOGENOM Q12X08; -.
Genome annotation databases
CMR Q12X08; Mbur_1088.
Other
ProtoNet Q12X08.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
ATP-binding; Cell cycle; Cell division; Complete proteome; DNA damage; DNA recombination; DNA repair; DNA replication; Ligase; Nucleotide-binding.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   567  567     DNA ligase. PRO_1000049869
ACT_SITE   262   262        N6-AMP-lysine intermediate (By similarity). 
Sequence information
Length: 567 AA [This is the length of the unprocessed precursor] Molecular weight: 62743 Da [This is the MW of the unprocessed precursor] CRC64: 3942FDE27D6C32F0 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MTDFKEFADV CKQIEHISSS LEMTDVVSDM LKSISTEELP VVTHFVMGDV FPAWSVEQLG 

        70         80         90        100        110        120 
VGTSLLYSAL SESSGLSLKE IEDLVRSTGD IGETAVAALG KKKKNKKKNQ ASLSFFSEDA 

       130        140        150        160        170        180 
ASVSISIMDV FERFLDISRY SGAGSQSSKM RNLQFLFNSS SSEEARYLAR LTIEDLRIGV 

       190        200        210        220        230        240 
GEGIVRDAIS KAFDVPAGDI ERGFMLTNDL GLVAVAAKEG GIEEISKLRM ELDRPIKMML 

       250        260        270        280        290        300 
AQVTPSIEAA IKDLGMLAVE WKFDGARVQI HKKGDSINIF SRRLENVTLS LPDIVEAVKL 

       310        320        330        340        350        360 
HVKADSAILE GEAVAVDENG APRAFQDILK RFRRKYDVET MVREIPLTLN LFDILYLNGD 

       370        380        390        400        410        420 
VLMDQSLLRR REQLVACVEN CDSIKVDEQV LTDDVNVVND IYAAALNGGH EGVMLKNPEA 

       430        440        450        460        470        480 
SYSPGKRGKN WLKKKPIMET LDLVVIAAEW GYGKRANLIG SYALACFDPE DGKFLPIGKV 

       490        500        510        520        530        540 
ATGFSDEQLA ELTEVFSELI IGESGREIEL KPDVVFEIAF EEIQKSTNYG SGYALRFPRL 

       550        560 
VNVREDKSPE EAETIDRIES IYLSQRG
Q12X08 in FASTA format

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