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UniProtKB/Swiss-Prot entry Q12QQ5

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name CYSI_SHEDO
Primary accession number Q12QQ5
Secondary accession numbers None
Integrated into Swiss-Prot on June 26, 2007
Sequence was last modified on August 22, 2006 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 21)
Name and origin of the protein
Protein name Sulfite reductase [NADPH] hemoprotein beta-component
Synonyms SIR-HP
SIRHP
EC 1.8.1.2
Gene name
Name: cysI
OrderedLocusNames: Sden_0933
From
Shewanella denitrificans (strain OS217 / ATCC BAA-1090 / DSM 15013) [TaxID: 318161] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Alteromonadales; Shewanellaceae; Shewanella.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Kiss H., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Lykidis A., Richardson P.;
"Complete sequence of Shewanella denitrificans OS217.";
Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases.
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CP000302; ABE54221.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_561944.1; -.
3D structure databases
ModBase Q12QQ5.
Enzyme and pathway databases
BioCyc SDEN318161:SDEN_0933-MON; -.
Ontologies
GO
GO:0009337; Cellular component: sulfite reductase complex (NADPH) (inferred from electronic annotation from InterPro).
GO:0051539; Molecular function: 4 iron, 4 sulfur cluster binding (inferred from electronic annotation from InterPro).
GO:0009055; Molecular function: electron carrier activity (inferred from electronic annotation from InterPro).
GO:0020037; Molecular function: heme binding (inferred from electronic annotation from InterPro).
GO:0005506; Molecular function: iron ion binding (inferred from electronic annotation from UniProtKB-KW).
GO:0050661; Molecular function: NADP binding (inferred from electronic annotation from InterPro).
GO:0004783; Molecular function: sulfite reductase (NADPH) activity (inferred from electronic annotation from HAMAP).
GO:0019344; Biological process: cysteine biosynthetic process (inferred from electronic annotation from UniProtKB-KW).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
GO:0000103; Biological process: sulfate assimilation (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_01540; -; 1.
PBIL [Tree]
InterPro IPR011786; CysI.
IPR006066; Nir_Si_BS.
IPR006067; Nir_Sir_4Fe4S.
IPR005117; NiRdtase/SiRdtase_haem-b_fer.
Graphical view of domain structure.
Pfam PF01077; NIR_SIR; 1.
PF03460; NIR_SIR_ferr; 2.
Pfam graphical view of domain structure.
PRINTS PR00397; SIROHAEM.
TIGRFAMs TIGR02041; CysI; 1.
PROSITE PS00365; NIR_SIR; 1.
Genome annotation databases
GeneID 4016878; -.
GenomeReviews CP000302_GR; Sden_0933.
KEGG sdn:Sden_0933; -.
NMPDR fig|318161.14.peg.914; -.
Phylogenomic databases
HOGENOM Q12QQ5; -.
Genome annotation databases
CMR Q12QQ5; Sden_0933.
Other
ProtoNet Q12QQ5.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
4Fe-4S; Amino-acid biosynthesis; Complete proteome; Cysteine biosynthesis; Heme; Iron; Iron-sulfur; Metal-binding; NADP; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   562  562     Sulfite reductase [NADPH] hemoprotein beta-component. PRO_0000292963
METAL   426   426        Iron-sulfur (4Fe-4S) (By similarity). 
METAL   432   432        Iron-sulfur (4Fe-4S) (By similarity). 
METAL   471   471        Iron-sulfur (4Fe-4S) (By similarity). 
METAL   475   475        Iron (siroheme axial ligand) (By similarity). 
METAL   475   475        Iron-sulfur (4Fe-4S) (By similarity). 
Sequence information
Length: 562 AA [This is the length of the unprocessed precursor] Molecular weight: 62333 Da [This is the MW of the unprocessed precursor] CRC64: 85847875212193C6 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MSEQKLAVNE YLKTDSDYLR GTIQEGLDTQ VTGSFSDGDQ QLIKFHGFYQ QDDRDLRNER 

        70         80         90        100        110        120 
KEQKLEPLYS FMLRARVPGG ICTPAQWLDV DKISSTLTTS NSIRLTTRQT FQYHGIPKRN 

       130        140        150        160        170        180 
LKTLIQGLDK AALDSIAACG DVNRNVMCNP NPVESKLHAQ AYAVAKELSD HLLPHTRAYA 

       190        200        210        220        230        240 
EIWLDEEKLV GETVEPVYGN TYLPRKFKMA VSVPPDNDVD VYTNDLGFIA IAEDGQLVGF 

       250        260        270        280        290        300 
NLVAGGGMGS THGEVETFPR LADDFGFIKT ADVIKFAEAV MTVQRDWGNR VVRKRARLKY 

       310        320        330        340        350        360 
TIVDHGFDAF KAEVENRAGV KFAPKRDVVI GDRGDRYGWV EGIDSKWHLT LFIESGRIKD 

       370        380        390        400        410        420 
LPGQTLQTGL REIAKIHKGD FRMTSNQNMI IAGVAAEDKA EIEGLARKHG LMGQVLTGTR 

       430        440        450        460        470        480 
GHSIACVALP TCPLAMAEAE RYFPEFIDHI DALQAKHGIS DQSIVVRMTG CPNGCARPFA 

       490        500        510        520        530        540 
AEIGLVGKAP GRYNLYLGAN FEGTRLNKMH KENIQEAEIL AELDTLFGRY ATERDAGETF 

       550        560 
GNFTVRIGVV KAVNDAAKDF HG
Q12QQ5 in FASTA format

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