ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!
Search for

UniProtKB/Swiss-Prot entry Q12729

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

Note: most headings are clickable, even if they don't appear as links. They link to the user manual or other documents.
Entry information
Entry name LAC1_PLEOS
Primary accession number Q12729
Secondary accession numbers None
Integrated into Swiss-Prot on November 1, 1997
Sequence was last modified on November 1, 1996 (Sequence version 1)
Annotations were last modified on    September 2, 2008 (Entry version 47)
Name and origin of the protein
Protein name Laccase-1 [Precursor]
Synonyms EC 1.10.3.2
Benzenediol:oxygen oxidoreductase 1
Urishiol oxidase 1
Diphenol oxidase 1
Gene name
Name: POX1
From
Pleurotus ostreatus (Oyster mushroom) (White-rot fungus) [TaxID: 5322] 
Taxonomy Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes; Agaricomycetidae; Agaricales; Pleurotaceae; Pleurotus.
Protein existence 2: Evidence at transcript level;
References
[1]
 NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA].
STRAIN=Florida;
TISSUE=Mycelium;
PubMed=7793961 [NCBI, ExPASy, EBI, Israel, Japan]
Giardina P., Cannio R., Martirani L., Marzullo L., Palmieri G., Sannia G.;
"Cloning and sequencing of a laccase gene from the lignin-degrading basidiomycete Pleurotus ostreatus.";
Appl. Environ. Microbiol. 61:2408-2413(1995).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
Z34847; CAA84356.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
Z22591; CAA80305.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR S49120; S49120.
3D structure databases
HSSP Q12718; 1GYC. [HSSP ENTRY / PDB]
ModBase Q12729.
Family and domain databases
InterPro IPR001117; Cu-oxidase.
IPR011706; Cu-oxidase_2.
IPR011707; Cu-oxidase_3.
IPR002355; Cu_oxidase_Cu_BS.
IPR008972; Cupredoxin.
Graphical view of domain structure.
Gene3D G3DSA:2.60.40.420; Cupredoxin; 3.
Pfam PF00394; Cu-oxidase; 1.
PF07731; Cu-oxidase_2; 1.
PF07732; Cu-oxidase_3; 1.
Pfam graphical view of domain structure.
PROSITE PS00079; MULTICOPPER_OXIDASE1; 2.
PS00080; MULTICOPPER_OXIDASE2; 1.
BLOCKS Q12729.
Other
ProtoNet Q12729.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Copper; Glycoprotein; Lignin degradation; Metal-binding; Oxidoreductase; Repeat; Secreted; Signal.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
SIGNAL   1    23  23     Potential. 
CHAIN   24   529  506     Laccase-1. PRO_0000002929
DOMAIN   25   159  135     Plastocyanin-like 1. 
DOMAIN   170   312  143     Plastocyanin-like 2. 
DOMAIN   380   499  120     Plastocyanin-like 3. 
METAL   96    96        Copper 1; type 2 (By similarity). 
METAL   98    98        Copper 2; type 3 (By similarity). 
METAL   141   141        Copper 2; type 3 (By similarity). 
METAL   143   143        Copper 3; type 3 (By similarity). 
METAL   425   425        Copper 4; type 1 (By similarity). 
METAL   428   428        Copper 1; type 2 (By similarity). 
METAL   430   430        Copper 3; type 3 (By similarity). 
METAL   481   481        Copper 3; type 3 (By similarity). 
METAL   482   482        Copper 4; type 1 (By similarity). 
METAL   483   483        Copper 2; type 3 (By similarity). 
METAL   487   487        Copper 4; type 1 (By similarity). 
CARBOHYD   57    57        N-linked (GlcNAc...) (Potential). 
CARBOHYD   239   239        N-linked (GlcNAc...) (Potential). 
CARBOHYD   282   282        N-linked (GlcNAc...) (Potential). 
CARBOHYD   465   465        N-linked (GlcNAc...) (Potential). 
Sequence information
Length: 529 AA [This is the length of the unprocessed precursor] Molecular weight: 56580 Da [This is the MW of the unprocessed precursor] CRC64: 40110AFC4886882F [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MFPGARILAT LTLALHLLHG THAAIGPTGD MYIVNEDVSP DGFTRSAVVA RSDPTTNGTS 

        70         80         90        100        110        120 
ETLTGVLVQG NKGDNFQLNV LNQLSDTTML KTTSIHWHGF FQSGSTWADG PAFVNQCPIA 

       130        140        150        160        170        180 
SGNSFLYDFN VPDQAGTFWY HSHLSTQYCD GLRGPFIVYD PSDPHLSLYD VDNADTIITL 

       190        200        210        220        230        240 
EDWYHVVAPQ NAVLPTADST LINGKGRFAG GPTSALAVIN VESNKRYRFR LISMSCDPNF 

       250        260        270        280        290        300 
TFSIDGHSLQ VIEADAVNIV PIVVDSIQIF AGQRYSFVLN ANQTVDNYWI RADPNLGSTG 

       310        320        330        340        350        360 
FDGGINSAIL RYAGATEDDP TTTSSTSTPL EETNLVPLEN PGAPGPAVPG GADININLAM 

       370        380        390        400        410        420 
AFDVTNFELT INGSPFKAPT APVLLQILSG ATTAASLLPS GSIYSLEANK VVEISIPALA 

       430        440        450        460        470        480 
VGGPHPFHLH GHTFDVIRSA GSTTYNFDTP ARRDVVNTGT DANDNVTIRF VTDNPGPWFL 

       490        500        510        520 
HCHIDWHLEI GLAVVFAEDV TSITAPPAAW DDLCPIYDAL SDSDKGGIA
Q12729 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

BLAST logo BLAST submission on ExPASy/SIB
or at NCBI (USA) 		Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Hosted by kr flag YPRC Korea Mirror sites: Australia Brazil Canada China Switzerland
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!