ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!
Search for

UniProtKB/Swiss-Prot entry Q12542

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

Note: most headings are clickable, even if they don't appear as links. They link to the user manual or other documents.
Entry information
Entry name LAC2_AGABI
Primary accession number Q12542
Secondary accession numbers None
Integrated into Swiss-Prot on November 1, 1997
Sequence was last modified on November 1, 1996 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 48)
Name and origin of the protein
Protein name Laccase-2 [Precursor]
Synonyms EC 1.10.3.2
Laccase II
Benzenediol:oxygen oxidoreductase 2
Urishiol oxidase 2
Diphenol oxidase 2
Gene name
Name: lcc2
From
Agaricus bisporus (Common mushroom) [TaxID: 5341] 
Taxonomy Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes; Agaricomycetidae; Agaricales; Agaricaceae; Agaricus.
Protein existence 1: Evidence at protein level;
References
[1]
 NUCLEOTIDE SEQUENCE [MRNA], AND PARTIAL PROTEIN SEQUENCE.
STRAIN=D649;
PubMed=8360614 [NCBI, ExPASy, EBI, Israel, Japan]
Perry C.R., Smith M., Britnell C.H., Wood D.A., Thurston C.F.;
"Identification of two laccase genes in the cultivated mushroom Agaricus bisporus.";
J. Gen. Microbiol. 139:1209-1218(1993).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
L10663; AAA17035.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
3D structure databases
HSSP Q12718; 1GYC. [HSSP ENTRY / PDB]
ModBase Q12542.
Ontologies
GO
GO:0008471; Molecular function: laccase activity (inferred from electronic annotation from EC).
QuickGo view.
Family and domain databases
InterPro IPR001117; Cu-oxidase.
IPR011706; Cu-oxidase_2.
IPR011707; Cu-oxidase_3.
IPR002355; Cu_oxidase_Cu_BS.
IPR008972; Cupredoxin.
Graphical view of domain structure.
Gene3D G3DSA:2.60.40.420; Cupredoxin; 3.
Pfam PF00394; Cu-oxidase; 1.
PF07731; Cu-oxidase_2; 1.
PF07732; Cu-oxidase_3; 1.
Pfam graphical view of domain structure.
PROSITE PS00079; MULTICOPPER_OXIDASE1; 2.
PS00080; MULTICOPPER_OXIDASE2; 1.
BLOCKS Q12542.
Other
ProtoNet Q12542.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Copper; Direct protein sequencing; Glycoprotein; Lignin degradation; Metal-binding; Oxidoreductase; Repeat; Secreted; Signal.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
SIGNAL   1    19  19      
CHAIN   20   520  501     Laccase-2. PRO_0000002919
DOMAIN   21   145  125     Plastocyanin-like 1. 
DOMAIN   157   305  149     Plastocyanin-like 2. 
DOMAIN   375   488  114     Plastocyanin-like 3. 
METAL   82    82        Copper 1 (type 2) (By similarity). 
METAL   84    84        Copper 2 (type 3) (By similarity). 
METAL   127   127        Copper 2 (type 3) (By similarity). 
METAL   129   129        Copper 3 (type 3) (By similarity). 
METAL   417   417        Copper 4 (type 1) (By similarity). 
METAL   420   420        Copper 1 (type 2) (By similarity). 
METAL   422   422        Copper 3 (type 3) (By similarity). 
METAL   470   470        Copper 3 (type 3) (By similarity). 
METAL   471   471        Copper 4 (type 1) (By similarity). 
METAL   472   472        Copper 2 (type 3) (By similarity). 
METAL   476   476        Copper 4 (type 1) (By similarity). 
CARBOHYD   108   108        N-linked (GlcNAc...) (Potential). 
CARBOHYD   241   241        N-linked (GlcNAc...) (Potential). 
CARBOHYD   299   299        N-linked (GlcNAc...) (Potential). 
CARBOHYD   454   454        N-linked (GlcNAc...) (Potential). 
CARBOHYD   492   492        N-linked (GlcNAc...) (Potential). 
Sequence information
Length: 520 AA [This is the length of the unprocessed precursor] Molecular weight: 57823 Da [This is the MW of the unprocessed precursor] CRC64: EF100145F0A697AA [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MRFSNAFVLV AACISSVLAD TKTFNFDLVN TRLAPDGFER DTVVINGEFP GTLVQVNKGD 

        70         80         90        100        110        120 
SVRIPVNNKL TSSTMRRSVS IHWHGFFQAR TSGQDGPAFV NQCPQPPNTT FTYEFSVADE 

       130        140        150        160        170        180 
SGTFWYHSHL STQYCDGLRG AFVVYDPEDP LGHLYDVDDE TTVITLAEWY HVLAPDINNE 

       190        200        210        220        230        240 
FFSSGIIPVQ DSGLINGKGR FNGGPETPFA VVNVEQGKRY RFRVIAISCR PFFTFSVDNH 

       250        260        270        280        290        300 
NLTFMEADSV EHDPVEIQNV DIYAAQRVSV ILNANQPVDN YWMRAPMTGG NPDRNPNLNI 

       310        320        330        340        350        360 
SLTLAILRYK GAPEVEPTTV NVPGHKLLDQ EMHPIAQEGP GKLGDGPPDK HITLNIAQPN 

       370        380        390        400        410        420 
APFFDINGIS YISPTVPVLL QILSGAKRPE DVLPSEQIFF VPKNSLIEVN IPGEGAHPFH 

       430        440        450        460        470        480 
LHGHNFDVVL ASNDDTFNFV NPPRRDVYPI NGGNTTFRFF TDNPGAWFLH CHIDWHLEAG 

       490        500        510        520 
LAIVFAEAPE DNVSGPQSQI TPQDWLDLCP EYNAIEPEFQ
Q12542 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

BLAST logo BLAST submission on ExPASy/SIB
or at NCBI (USA) 		Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Hosted by kr flag YPRC Korea Mirror sites: Australia Brazil Canada China Switzerland
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!