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UniProtKB/Swiss-Prot entry Q12541

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name LAC1_AGABI
Primary accession number Q12541
Secondary accession numbers None
Integrated into Swiss-Prot on November 1, 1997
Sequence was last modified on November 1, 1996 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 47)
Name and origin of the protein
Protein name Laccase-1 [Precursor]
Synonyms EC 1.10.3.2
Laccase I
Benzenediol:oxygen oxidoreductase 1
Urishiol oxidase 1
Diphenol oxidase 1
Gene name
Name: lcc1
From
Agaricus bisporus (Common mushroom) [TaxID: 5341] 
Taxonomy Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes; Agaricomycetidae; Agaricales; Agaricaceae; Agaricus.
Protein existence 1: Evidence at protein level;
References
[1]
 NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND PARTIAL PROTEIN SEQUENCE.
STRAIN=D649;
TISSUE=Mycelium;
PubMed=8360614 [NCBI, ExPASy, EBI, Israel, Japan]
Perry C.R., Smith M., Britnell C.H., Wood D.A., Thurston C.F.;
"Identification of two laccase genes in the cultivated mushroom Agaricus bisporus.";
J. Gen. Microbiol. 139:1209-1218(1993).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
L10664; AAC18877.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
3D structure databases
HSSP Q9Y780; 1HFU. [HSSP ENTRY / PDB]
ModBase Q12541.
Ontologies
GO
GO:0008471; Molecular function: laccase activity (inferred from electronic annotation from EC).
QuickGo view.
Family and domain databases
InterPro IPR001117; Cu-oxidase.
IPR011706; Cu-oxidase_2.
IPR011707; Cu-oxidase_3.
IPR002355; Cu_oxidase_Cu_BS.
IPR008972; Cupredoxin.
Graphical view of domain structure.
Gene3D G3DSA:2.60.40.420; Cupredoxin; 3.
Pfam PF00394; Cu-oxidase; 1.
PF07731; Cu-oxidase_2; 1.
PF07732; Cu-oxidase_3; 1.
Pfam graphical view of domain structure.
PROSITE PS00079; MULTICOPPER_OXIDASE1; 2.
PS00080; MULTICOPPER_OXIDASE2; 1.
BLOCKS Q12541.
Other
ProtoNet Q12541.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Copper; Direct protein sequencing; Glycoprotein; Lignin degradation; Metal-binding; Oxidoreductase; Repeat; Secreted; Signal.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
SIGNAL   1    19  19      
CHAIN   20   520  501     Laccase-1. PRO_0000002918
DOMAIN   21   145  125     Plastocyanin-like 1. 
DOMAIN   157   305  149     Plastocyanin-like 2. 
DOMAIN   375   488  114     Plastocyanin-like 3. 
METAL   82    82        Copper 1 (type 2) (By similarity). 
METAL   84    84        Copper 2 (type 3) (By similarity). 
METAL   127   127        Copper 2 (type 3) (By similarity). 
METAL   129   129        Copper 3 (type 3) (By similarity). 
METAL   417   417        Copper 4 (type 1) (By similarity). 
METAL   420   420        Copper 1 (type 2) (By similarity). 
METAL   422   422        Copper 3 (type 3) (By similarity). 
METAL   470   470        Copper 3 (type 3) (By similarity). 
METAL   471   471        Copper 4 (type 1) (By similarity). 
METAL   472   472        Copper 2 (type 3) (By similarity). 
METAL   476   476        Copper 4 (type 1) (By similarity). 
CARBOHYD   108   108        N-linked (GlcNAc...) (Potential). 
CARBOHYD   239   239        N-linked (GlcNAc...) (Potential). 
CARBOHYD   299   299        N-linked (GlcNAc...) (Potential). 
CARBOHYD   454   454        N-linked (GlcNAc...) (Potential). 
CARBOHYD   492   492        N-linked (GlcNAc...) (Potential). 
Sequence information
Length: 520 AA [This is the length of the unprocessed precursor] Molecular weight: 58099 Da [This is the MW of the unprocessed precursor] CRC64: 943DB3F23297B891 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MRLSNALVLV AACISSVVAK TRTFDFDLVN TRLAPDGFER DTVVINGEFP GTLIQVNKGD 

        70         80         90        100        110        120 
SVRIPLHNKL TSPTMRRSVS IHWHGFFQAR TSGQDGPSFV NQCPQPPNTT FTYEFSVAEQ 

       130        140        150        160        170        180 
SGTFWYHSHL STQYCDGLRG AFIVYDPRDP LRHLYDVDDE STVITLAEWY HILAPDATNE 

       190        200        210        220        230        240 
FFSSGIIPVQ DSGLINGKGR FNGGPLTPFA VVNVRRGKRY RLRVIAISCR PFFTFSVDNH 

       250        260        270        280        290        300 
SLVFMEADGV EHDPVEVQNV DIYAAQRVSV ILHANQPIDN YWIRAPMTGG NPDRNPNLNI 

       310        320        330        340        350        360 
SLTLAILRYH GARHVEPTTV NVPGHKLLDQ EMHPIRQEGP GKLGDGPPDK HITLNIAQPN 

       370        380        390        400        410        420 
APFFDINGIS YISPTVPVLL QILSGAKRPE DVLPSEQIFF VPKNSLIEVN IPGEGAHPFH 

       430        440        450        460        470        480 
LHGHNFDVVL ASNDDTFNFK NPPRRDVYPI NGGNTTFRFF TDNPGAWFLH CHIDWHLEAG 

       490        500        510        520 
LAIVFAEAPE DNVSGPQSQI TPQDWLDLCP EYNAIEPEFQ
Q12541 in FASTA format

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