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UniProtKB/Swiss-Prot entry Q12298


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name YD061_YEAST
Primary accession number Q12298
Secondary accession numbers None
Integrated into Swiss-Prot on June 27, 2006
Sequence was last modified on November 1, 1996 (Sequence version 1)
Annotations were last modified on    December 16, 2008 (Entry version 62)
Name and origin of the protein
Protein name Uncharacterized ABC transporter ATP-binding protein YDR061W
Synonyms None
Gene name
OrderedLocusNames: YDR061W
ORFNames: D4241
From
Saccharomyces cerevisiae (Baker's yeast) [TaxID: 4932] 
Taxonomy Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces.
Protein existence 1: Evidence at protein level;
References
[1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
DOI=10.1002/(SICI)1097-0061(199601)12:1<85::AID-YEA890>3.0.CO;2-U; PubMed=8789263 [NCBI, ExPASy, EBI, Israel, Japan]
Brandt P., Ramlow S., Otto B., Bloecker H.;
"Nucleotide sequence analysis of a 32,500 bp region of the right arm of Saccharomyces cerevisiae chromosome IV.";
Yeast 12:85-90(1996).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 204508 / S288c;
PubMed=9169867 [NCBI, ExPASy, EBI, Israel, Japan]
Jacq C., Alt-Moerbe J., Andre B., Arnold W., Bahr A., Ballesta J.P.G., Bargues M., Baron L., Becker A., Biteau N., Bloecker H., Blugeon C., Boskovic J., Brandt P., Brueckner M., Buitrago M.J., Coster F., Delaveau T., del Rey F., Dujon B., Eide L.G., Garcia-Cantalejo J.M., Goffeau A., Gomez-Peris A., Granotier C., Hanemann V., Hankeln T., Hoheisel J.D., Jaeger W., Jimenez A., Jonniaux J.-L., Kraemer C., Kuester H., Laamanen P., Legros Y., Louis E.J., Moeller-Rieker S., Monnet A., Moro M., Mueller-Auer S., Nussbaumer B., Paricio N., Paulin L., Perea J., Perez-Alonso M., Perez-Ortin J.E., Pohl T.M., Prydz H., Purnelle B., Rasmussen S.W., Remacha M.A., Revuelta J.L., Rieger M., Salom D., Saluz H.P., Saiz J.E., Saren A.-M., Schaefer M., Scharfe M., Schmidt E.R., Schneider C., Scholler P., Schwarz S., Soler-Mira A., Urrestarazu L.A., Verhasselt P., Vissers S., Voet M., Volckaert G., Wagner G., Wambutt R., Wedler E., Wedler H., Woelfl S., Harris D.E., Bowman S., Brown D., Churcher C.M., Connor R., Dedman K., Gentles S., Hamlin N., Hunt S., Jones L., McDonald S., Murphy L.D., Niblett D., Odell C., Oliver K., Rajandream M.A., Richards C., Shore L., Walsh S.V., Barrell B.G., Dietrich F.S., Mulligan J.T., Allen E., Araujo R., Aviles E., Berno A., Carpenter J., Chen E., Cherry J.M., Chung E., Duncan M., Hunicke-Smith S., Hyman R.W., Komp C., Lashkari D., Lew H., Lin D., Mosedale D., Nakahara K., Namath A., Oefner P., Oh C., Petel F.X., Roberts D., Schramm S., Schroeder M., Shogren T., Shroff N., Winant A., Yelton M.A., Botstein D., Davis R.W., Johnston M., Andrews S., Brinkman R., Cooper J., Ding H., Du Z., Favello A., Fulton L., Gattung S., Greco T., Hallsworth K., Hawkins J., Hillier L.W., Jier M., Johnson D., Johnston L., Kirsten J., Kucaba T., Langston Y., Latreille P., Le T., Mardis E., Menezes S., Miller N., Nhan M., Pauley A., Peluso D., Rifkin L., Riles L., Taich A., Trevaskis E., Vignati D., Wilcox L., Wohldman P., Vaudin M., Wilson R., Waterston R., Albermann K., Hani J., Heumann K., Kleine K., Mewes H.-W., Zollner A., Zaccaria P.;
"The nucleotide sequence of Saccharomyces cerevisiae chromosome IV.";
Nature 387:75-78(1997).
[3]
INDUCTION.
DOI=10.1074/jbc.M309580200; PubMed=14512416 [NCBI, ExPASy, EBI, Israel, Japan]
Lucau-Danila A., Delaveau T., Lelandais G., Devaux F., Jacq C.;
"Competitive promoter occupancy by two yeast paralogous transcription factors controlling the multidrug resistance phenomenon.";
J. Biol. Chem. 278:52641-52650(2003).
[4]
SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
DOI=10.1038/nature02026; PubMed=14562095 [NCBI, ExPASy, EBI, Israel, Japan]
Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W., Weissman J.S., O'Shea E.K.;
"Global analysis of protein localization in budding yeast.";
Nature 425:686-691(2003).
[5]
LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
DOI=10.1038/nature02046; PubMed=14562106 [NCBI, ExPASy, EBI, Israel, Japan]
Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S.;
"Global analysis of protein expression in yeast.";
Nature 425:737-741(2003).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
X84162; CAA58977.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
Z49209; CAA89090.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
Z74357; CAA98879.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR S54045; S54045.
RefSeq NP_010346.1; -.
3D structure databases
ModBase Q12298.
Protein-protein interaction databases
DIP DIP:1817N; -.
IntAct Q12298; 9.
Organism-specific databases
CYGD YDR061w; -.
SGD S000002468; YDR061W.
Yeast-GFP YDR061W.
Gene expression databases
GermOnline YDR061W; Saccharomyces cerevisiae.
Ontologies
GO
GO:0005739; Cellular component: mitochondrion (inferred from electronic annotation from UniProtKB-KW).
GO:0005524; Molecular function: ATP binding (inferred from electronic annotation from InterPro).
GO:0016887; Molecular function: ATPase activity (inferred from electronic annotation from InterPro).
GO:0005515; Molecular function: protein binding (inferred from physical interaction from IntAct).
GO:0006810; Biological process: transport (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
InterPro IPR003593; AAA+_ATPase_core.
IPR003439; ABC_transporter-like.
Graphical view of domain structure.
Pfam PF00005; ABC_tran; 2.
Pfam graphical view of domain structure.
ProDom PD000006; ABC_transporter; 1.
[Domain structure / List of seq. sharing at least 1 domain]
SMART SM00382; AAA; 1.
SMART graphical view of domain structure.
PROSITE PS00211; ABC_TRANSPORTER_1; FALSE_NEG.
PS50893; ABC_TRANSPORTER_2; 2.
PROSITE graphical view of domain structure (profiles).
Proteomic databases
PeptideAtlas Q12298; -.
Genome annotation databases
Ensembl YDR061W; Saccharomyces cerevisiae. [Contig view]
GeneID 851633; -.
GenomeReviews Z71256_GR; YDR061W.
KEGG sce:YDR061W; -.
NMPDR fig|4932.3.peg.1091; -.
Phylogenomic databases
HOGENOM Q12298; -.
Other
LinkHub Q12298; -.
NextBio 969185; -.
ProtoNet Q12298.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
ATP-binding; Complete proteome; Mitochondrion; Nucleotide-binding; Repeat; Transport.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   539  539     Uncharacterized ABC transporter ATP-binding protein YDR061W. PRO_0000244440
DOMAIN   8   265  258     ABC transporter 1. 
DOMAIN   307   537  231     ABC transporter 2. 
NP_BIND   339   346  8     ATP (Potential). 
Sequence information
Length: 539 AA [This is the length of the unprocessed precursor] Molecular weight: 61191 Da [This is the MW of the unprocessed precursor] CRC64: 3F27AF363EBED838 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MSTNKFVVRI TNALFKSSLA SNSPPVYPKR IRHFEILPNE KWVIWGPGKG KFLDVLNNKY 

        70         80         90        100        110        120 
ICEPPLSLRF GFLKESSNIL PRIEQVAFKG VMPTAHLSAR YEYFKDDYDQ TCKQFIFDKA 

       130        140        150        160        170        180 
SGSNAVSYKV ETNNRQINME LYNALVENLN LSSLQDRWVM GLSNGQMRRA RLARSILKEP 

       190        200        210        220        230        240 
DLLLIDDPFL GLDPAAIATI SQFLAKYDSI EVSGGCPIVI GLRYQDTIPA WCTHICCVDE 

       250        260        270        280        290        300 
KNGILFEGPI EKLQSKMDET RSRALKELEQ LKKASNSKED ISINDLICIH PMYGKKEHEI 

       310        320        330        340        350        360 
IKMPHLIELD GLSVSYKGEA VLENLHWKVQ PGSKWHIRGD NGSGKSTLLS LLTAEHPQSW 

       370        380        390        400        410        420 
NSRVIDNGVP RRTGKTNYFD LNSKIGMSSP ELHAIFLKNA GGRLNIRESV ATGYHEASSN 

       430        440        450        460        470        480 
NYLPIWKRLD KNSQEIVNMY LKYFGLDKDA DSVLFEQLSV SDQKLVLFVR SLIKMPQILI 

       490        500        510        520        530 
LDEAFSGMEV EPMMRCHEFL EEWPGTVLVV AHVAEETPKC AHYLRLISPG EYEIGDMEN 

Q12298 in FASTA format

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View entry in raw text format (no links)
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