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UniProtKB/Swiss-Prot entry Q12007


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name ERR1_YEAST
Primary accession number Q12007
Secondary accession number Q7LGJ4
Integrated into Swiss-Prot on August 31, 2004
Sequence was last modified on November 1, 1996 (Sequence version 1)
Annotations were last modified on    December 16, 2008 (Entry version 66)
Name and origin of the protein
Protein name Enolase-related protein 1/2
Synonyms EC 4.2.1.11
2-phosphoglycerate dehydratase
2-phospho-D-glycerate hydro-lyase
Gene names
Name: ERR1
OrderedLocusNames: YOR393W
and
Name: ERR2
OrderedLocusNames: YPL281C
From
Saccharomyces cerevisiae (Baker's yeast) [TaxID: 4932] 
Taxonomy Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces.
Protein existence 1: Evidence at protein level;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] (YOR393W).
STRAIN=ATCC 96604 / S288c / FY1679;
PubMed=9169874 [NCBI, ExPASy, EBI, Israel, Japan]
Dujon B., Albermann K., Aldea M., Alexandraki D., Ansorge W., Arino J., Benes V., Bohn C., Bolotin-Fukuhara M., Bordonne R., Boyer J., Camasses A., Casamayor A., Casas C., Cheret G., Cziepluch C., Daignan-Fornier B., Dang V.-D., de Haan M., Delius H., Durand P., Fairhead C., Feldmann H., Gaillon L., Galisson F., Gamo F.-J., Gancedo C., Goffeau A., Goulding S.E., Grivell L.A., Habbig B., Hand N.J., Hani J., Hattenhorst U., Hebling U., Hernando Y., Herrero E., Heumann K., Hiesel R., Hilger F., Hofmann B., Hollenberg C.P., Hughes B., Jauniaux J.-C., Kalogeropoulos A., Katsoulou C., Kordes E., Lafuente M.J., Landt O., Louis E.J., Maarse A.C., Madania A., Mannhaupt G., Marck C., Martin R.P., Mewes H.-W., Michaux G., Paces V., Parle-McDermott A.G., Pearson B.M., Perrin A., Pettersson B., Poch O., Pohl T.M., Poirey R., Portetelle D., Pujol A., Purnelle B., Ramezani Rad M., Rechmann S., Schwager C., Schweizer M., Sor F., Sterky F., Tarassov I.A., Teodoru C., Tettelin H., Thierry A., Tobiasch E., Tzermia M., Uhlen M., Unseld M., Valens M., Vandenbol M., Vetter I., Vlcek C., Voet M., Volckaert G., Voss H., Wambutt R., Wedler H., Wiemann S., Winsor B., Wolfe K.H., Zollner A., Zumstein E., Kleine K.;
"The nucleotide sequence of Saccharomyces cerevisiae chromosome XV.";
Nature 387:98-102(1997).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] (YPL281C).
STRAIN=ATCC 204511 / S288c / AB972;
PubMed=9169875 [NCBI, ExPASy, EBI, Israel, Japan]
Bussey H., Storms R.K., Ahmed A., Albermann K., Allen E., Ansorge W., Araujo R., Aparicio A., Barrell B.G., Badcock K., Benes V., Botstein D., Bowman S., Brueckner M., Carpenter J., Cherry J.M., Chung E., Churcher C.M., Coster F., Davis K., Davis R.W., Dietrich F.S., Delius H., DiPaolo T., Dubois E., Duesterhoeft A., Duncan M., Floeth M., Fortin N., Friesen J.D., Fritz C., Goffeau A., Hall J., Hebling U., Heumann K., Hilbert H., Hillier L.W., Hunicke-Smith S., Hyman R.W., Johnston M., Kalman S., Kleine K., Komp C., Kurdi O., Lashkari D., Lew H., Lin A., Lin D., Louis E.J., Marathe R., Messenguy F., Mewes H.-W., Mirtipati S., Moestl D., Mueller-Auer S., Namath A., Nentwich U., Oefner P., Pearson D., Petel F.X., Pohl T.M., Purnelle B., Rajandream M.A., Rechmann S., Rieger M., Riles L., Roberts D., Schaefer M., Scharfe M., Scherens B., Schramm S., Schroeder M., Sdicu A.-M., Tettelin H., Urrestarazu L.A., Ushinsky S., Vierendeels F., Vissers S., Voss H., Walsh S.V., Wambutt R., Wang Y., Wedler E., Wedler H., Winnett E., Zhong W.-W., Zollner A., Vo D.H., Hani J.;
"The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI.";
Nature 387:103-105(1997).
[3]
NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 120-437 (YOR393W).
STRAIN=ATCC 90839 / S288c / YP1;
PubMed=7785338 [NCBI, ExPASy, EBI, Israel, Japan]
Pryde F.E., Huckle T.C., Louis E.J.;
"Sequence analysis of the right end of chromosome XV in Saccharomyces cerevisiae: an insight into the structural and functional significance of sub-telomeric repeat sequences.";
Yeast 11:371-382(1995).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
Z75301; CAA99725.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
Z75302; CAA99728.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
Z73637; CAA98018.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
U23472; AAC48992.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR S67305; S67305.
RefSeq NP_015038.1; -.
NP_015042.1; -.
3D structure databases
HSSP Q9NDH8; 1OEP. [HSSP ENTRY / PDB]
ModBase Q12007.
Protein-protein interaction databases
DIP DIP:8882N; -.
IntAct Q12007; 3.
Organism-specific databases
CYGD YOR393w; -.
YPL281c; -.
SGD S000005920; ERR1.
S000006202; ERR2.
Yeast-GFP YOR393W.
Gene expression databases
GermOnline YOR393W; Saccharomyces cerevisiae.
YPL281C; Saccharomyces cerevisiae.
Ontologies
GO
GO:0000015; Cellular component: phosphopyruvate hydratase complex (inferred from electronic annotation from InterPro).
GO:0000287; Molecular function: magnesium ion binding (inferred from electronic annotation from UniProtKB-KW).
GO:0004634; Molecular function: phosphopyruvate hydratase activity (inferred from electronic annotation from InterPro).
GO:0005515; Molecular function: protein binding (inferred from physical interaction from IntAct).
GO:0006096; Biological process: glycolysis (inferred from electronic annotation from InterPro).
QuickGo view.
Family and domain databases
InterPro IPR000941; Enolase.
Graphical view of domain structure.
PANTHER PTHR11902; Enolase; 1.
Pfam PF00113; Enolase_C; 1.
PF03952; Enolase_N; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF001400; Enolase; 1.
PRINTS PR00148; ENOLASE.
ProDom PD000902; Enolase; 1.
[Domain structure / List of seq. sharing at least 1 domain]
TIGRFAMs TIGR01060; eno; 1.
PROSITE PS00164; ENOLASE; 1.
Genome annotation databases
Ensembl YOR393W; Saccharomyces cerevisiae. [Contig view]
YPL281C; Saccharomyces cerevisiae. [Contig view]
GeneID 854575; -.
855848; -.
KEGG sce:YOR393W; -.
sce:YPL281C; -.
Phylogenomic databases
HOGENOM Q12007; -.
Other
LinkHub Q12007; -.
NextBio 977033; -.
ProtoNet Q12007.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Glycolysis; Lyase; Magnesium; Metal-binding.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   437  437     Enolase-related protein 1/2. PRO_0000134064
REGION   373   376  4     Substrate binding (By similarity). 
ACT_SITE   212   212        Proton donor (By similarity). 
ACT_SITE   346   346        Proton acceptor (By similarity). 
METAL   247   247        Magnesium (By similarity). 
METAL   296   296        Magnesium (By similarity). 
METAL   321   321        Magnesium (By similarity). 
BINDING   160   160        Substrate (By similarity). 
BINDING   169   169        Substrate (By similarity). 
BINDING   296   296        Substrate (By similarity). 
BINDING   321   321        Substrate (By similarity). 
BINDING   397   397        Substrate (By similarity). 
CONFLICT   231   231        E -> K (in Ref. 3; AAC48992). 
Sequence information
Length: 437 AA [This is the length of the unprocessed precursor] Molecular weight: 47328 Da [This is the MW of the unprocessed precursor] CRC64: FAF09C00BE0E711C [This is a checksum on the sequence]
        10         20         30         40         50         60 
MSITKVHART VYDSRGNPTV EVEITTENGL FRAIVPSGAS TGIHEAVELR DGNKSEWMGK 

        70         80         90        100        110        120 
GVTKAVSNVN SIIGPALIKS ELCVTNQKGI DELMISLDGT SNKSRLGANA ILGVSLCVAR 

       130        140        150        160        170        180 
AAAAQKGITL YKYIAELADA RQDPFVIPVP FFNVLNGGAH AGGSLAMQEF KIAPVGAQSF 

       190        200        210        220        230        240 
AEAMRMGSEV YHHLKILAKE QYGPSAGNVG DEGGVAPDID TAEDALDMIV EAINICGYEG 

       250        260        270        280        290        300 
RVKVGIDSAP SVFYKDGKYD LNFKEPNSDP SHWLSPAQLA EYYHSLLKKY PIISLEDPYA 

       310        320        330        340        350        360 
EDDWSSWSAF LKTVNVQIIA DDLTCTNKTR IARAIEEKCA NTLLLKLNQI GTLTESIEAA 

       370        380        390        400        410        420 
NQAFDAGWGV MISHRSGETE DPFIADLVVG LRCGQIKSGA LSRSERLAKY NELLRIEEEL 

       430 
GDDCIYAGHR FHDGNKL 

Q12007 in FASTA format

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