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UniProtKB/Swiss-Prot entry Q0SRN5


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name TGT_CLOPS
Primary accession number Q0SRN5
Secondary accession numbers None
Integrated into Swiss-Prot on January 15, 2008
Sequence was last modified on September 5, 2006 (Sequence version 1)
Annotations were last modified on    November 4, 2008 (Entry version 19)
Name and origin of the protein
Protein name Queuine tRNA-ribosyltransferase
Synonyms EC 2.4.2.29
tRNA-guanine transglycosylase
Guanine insertion enzyme
Gene name
Name: tgt
OrderedLocusNames: CPR_1912
From
Clostridium perfringens (strain SM101 / Type A) [TaxID: 289380] [HAMAP proteome]
Taxonomy Bacteria; Firmicutes; Clostridia; Clostridiales; Clostridiaceae; Clostridium.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1101/gr.5238106; PubMed=16825665 [NCBI, ExPASy, EBI, Israel, Japan]
Myers G.S.A., Rasko D.A., Cheung J.K., Ravel J., Seshadri R., DeBoy R.T., Ren Q., Varga J., Awad M.M., Brinkac L.M., Daugherty S.C., Haft D.H., Dodson R.J., Madupu R., Nelson W.C., Rosovitz M.J., Sullivan S.A., Khouri H., Dimitrov G.I., Watkins K.L., Mulligan S., Benton J., Radune D., Fisher D.J., Atkins H.S., Hiscox T., Jost B.H., Billington S.J., Songer J.G., McClane B.A., Titball R.W., Rood J.I., Melville S.B., Paulsen I.T.;
"Skewed genomic variability in strains of the toxigenic bacterial pathogen, Clostridium perfringens.";
Genome Res. 16:1031-1040(2006).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CP000312; ABG87624.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_699222.1; -.
3D structure databases
ModBase Q0SRN5.
Ontologies
GO
GO:0008479; Molecular function: queuine tRNA-ribosyltransferase activity (inferred from electronic annotation from HAMAP).
GO:0008270; Molecular function: zinc ion binding (inferred from electronic annotation from UniProtKB-KW).
GO:0008616; Biological process: queuosine biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00168; -; 1.
PBIL [Tree]
InterPro IPR004803; QtRNA_ribo_trans.
IPR002616; tRNA_ribo_trans.
Graphical view of domain structure.
Gene3D G3DSA:3.20.20.105; tRNA_ribo_trans; 1.
PANTHER PTHR11962; tRNA_ribo_trans; 1.
Pfam PF01702; TGT; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR00430; Q_tRNA_tgt; 1.
TIGR00449; tgt_general; 1.
ProtoNet Q0SRN5.
Genome annotation databases
GeneID 4206159; -.
GenomeReviews CP000312_GR; CPR_1912.
KEGG cpr:CPR_1912; -.
TIGR CPR_1912; -.
Phylogenomic databases
HOGENOM Q0SRN5; -.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Glycosyltransferase; Metal-binding; Queuosine biosynthesis; Transferase; tRNA processing; Zinc.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   380  380     Queuine tRNA-ribosyltransferase. PRO_1000016783
ACT_SITE   93    93        Nucleophile (By similarity). 
METAL   313   313        Zinc (By similarity). 
METAL   315   315        Zinc (By similarity). 
METAL   318   318        Zinc (By similarity). 
METAL   344   344        Zinc (By similarity). 
BINDING   94    94        Substrate (By similarity). 
Sequence information
Length: 380 AA [This is the length of the unprocessed precursor] Molecular weight: 43186 Da [This is the MW of the unprocessed precursor] CRC64: 113B6B73540539D6 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MTKKRYTLLK KDGKARRGEF VTPHGTIQTP VFMNVGTLAA IKGAVSSMDL KEIGCQVELS 

        70         80         90        100        110        120 
NTYHLHLRPG DKIVKQMGGL HNFMNWDRPI LTDSGGFQVF SLAGMRKIKE EGVYFNSHID 

       130        140        150        160        170        180 
GRKIFMGPEE SMQIQSNLGS TIAMAFDECI PNPSTREYVE KSVARTTRWL ERCKKEMDRL 

       190        200        210        220        230        240 
NSLDDTVNKE QMLFGINQGG VYEDIRIEHA KTIREMDLDG YAIGGLAVGE THEEMYRVID 

       250        260        270        280        290        300 
AVVPHLPEDK PIYLMGVGLP SNILEAVERG VDFFDCVLPA RNGRHGHVFT KEGKINLMNA 

       310        320        330        340        350        360 
KFELDARPID EGCQCPACKN YTRAYIRHLF KAKEMLAMRL CVLHNLYFYN KLMEDIRDAI 

       370        380 
DGGYFAEFKA KKLEEWNGRA 

Q0SRN5 in FASTA format

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