NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1186/1471-2164-7-211; PubMed=16914037 [NCBI, ExPASy, EBI, Israel, Japan]
Gloeckner G., Schulte-Spechtel U., Schilhabel M., Felder M., Suehnel J., Wilske B., Platzer M.;
"Comparative genome analysis: selection pressure on the Borrelia vls cassettes is essential for infectivity.";
BMC Genomics 7:211-211(2006).

Comments

FUNCTION: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions (By similarity).
CATALYTIC ACTIVITY: NTP + H₂O = NDP + phosphate.
COFACTOR: Divalent cations (By similarity).
SUBUNIT: Homodimer (By similarity).
SIMILARITY: Belongs to the HAM1 NTPase family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

CP000395; ABH01514.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

RefSeq

YP_709690.1; -.

3D structure databases

ModBase

Q0SNR4.

Enzyme and pathway databases

BioCyc

BAFZ390236:BAPKO_0256-MON; -.

Ontologies

GO:0017111;	Molecular function: nucleoside-triphosphatase activity (inferred from electronic annotation from HAMAP).
QuickGo view.

Family and domain databases

HAMAP

MF_01405; -; 1.
PBIL [Tree]

InterPro

IPR002637; Ham1p_like.
Graphical view of domain structure.

PANTHER

PTHR11067; Ham1p_like; 1.

Pfam

PF01725; Ham1p_like; 1.
Pfam graphical view of domain structure.

TIGRFAMs

TIGR00042; Ham1p_like; 1.

ProtoNet

Q0SNR4.

Genome annotation databases

GeneID

4227720; -.

GenomeReviews

CP000395_GR; BAPKO_0256.

KEGG

baf:BAPKO_0256; -.

NMPDR

fig|390236.5.peg.308; -.

Phylogenomic databases

HOGENOM

Q0SNR4; -.

Genome annotation databases

CMR

Q0SNR4; BAPKO_0256.

Other

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Complete proteome; Hydrolase.

Features

Feature table viewer

`Key`	`From To`	`Length`		`Description`	`FTId`
`CHAIN`	`1 201`	`201`		`Nucleoside-triphosphatase.`	`PRO_1000068410`

Sequence information

Length: 201 AA [This is the length of the unprocessed precursor]

Molecular weight: 23170 Da [This is the MW of the unprocessed precursor]

CRC64: 38143D64C3B2B8E2 [This is a checksum on the sequence]

        10         20         30         40         50         60 
MKTLFFATTN ENKINEVKNI LDIPNLNLIV PQNFNIKETG KTFKENSLLK AKALFEILNK 

        70         80         90        100        110        120 
NQNVFGEDSG LCIEALNLEP GIYSKRYDTY KLCKKLSTNE KNQLILDLMK NEKNRHAYFI 

       130        140        150        160        170        180 
CNISYISKNR QISNFEGIIK GKIALSLNDD KNHGFGYDSI FLTKNNKKLS DLTLEEKNKI 

       190        200 
SHRGIAFSKF KKFLLESLFN S

Q0SNR4 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
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	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools