[1]	NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. STRAIN=cv. Nipponbare; DOI=10.1186/1741-7007-3-20; PubMed=16188032 [NCBI, ExPASy, EBI, Israel, Japan] The rice chromosomes 11 and 12 sequencing consortia; "The sequence of rice chromosomes 11 and 12, rich in disease resistance genes and recent gene duplications."; BMC Biol. 3:20-20(2005).
[2]	NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. STRAIN=cv. Nipponbare; DOI=10.1038/nature03895; PubMed=16100779 [NCBI, ExPASy, EBI, Israel, Japan] International rice genome sequencing project (IRGSP); "The map-based sequence of the rice genome."; Nature 436:793-800(2005).
[3]	GENOME REANNOTATION. STRAIN=cv. Nipponbare; DOI=10.1101/gr.5509507; PubMed=17210932 [NCBI, ExPASy, EBI, Israel, Japan] The rice annotation project (RAP); "Curated genome annotation of Oryza sativa ssp. japonica and comparative genome analysis with Arabidopsis thaliana."; Genome Res. 17:175-183(2007).

Comments

FUNCTION: Lignin degradation and detoxification of lignin-derived products (By similarity).
CATALYTIC ACTIVITY: 4 benzenediol + O₂ = 4 benzosemiquinone + 2 H₂O.
COFACTOR: Binds 4 copper ions per monomer (By similarity).
SUBCELLULAR LOCATION: Secreted, extracellular space, apoplast (Potential).
SIMILARITY: Belongs to the multicopper oxidase family.
SIMILARITY: Contains 3 plastocyanin-like domains.
SEQUENCE CAUTION:
- Sequence=ABA97328.1; Type=Erroneous gene model prediction;

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

DP000011; ABA97328.1; ALT_SEQ; Genomic_DNA.	[EMBL / GenBank / DDBJ] [CoDingSequence]
AP008218; BAF29537.1; -; Genomic_DNA.	[EMBL / GenBank / DDBJ] [CoDingSequence]

RefSeq

NP_001066518.1; -.

UniGene

Os.78608

3D structure databases

ModBase

Q0IP28.

Organism-specific databases

Gramene

Q2QUK8; -.

Family and domain databases

InterPro

IPR001117; Cu-oxidase.
IPR011706; Cu-oxidase_2.
IPR011707; Cu-oxidase_3.
IPR002355; Cu_oxidase_Cu_BS.
IPR008972; Cupredoxin.
IPR017761; Laccase.
Graphical view of domain structure.

Gene3D

G3DSA:2.60.40.420; Cupredoxin; 3.

Pfam

PF00394; Cu-oxidase; 1.
PF07731; Cu-oxidase_2; 1.
PF07732; Cu-oxidase_3; 1.
Pfam graphical view of domain structure.

PROSITE

PS00079; MULTICOPPER_OXIDASE1; FALSE_NEG.
PS00080; MULTICOPPER_OXIDASE2; 1.

BLOCKS

Q0IP28.

Genome annotation databases

GeneID

4351917; -.

KEGG

osa:4351917; -.

Other

ProtoNet

Q0IP28.

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Apoplast; Copper; Glycoprotein; Lignin degradation; Metal-binding; Oxidoreductase; Repeat; Secreted; Signal.

Features

Feature table viewer

Feature aligner

`Key`	`From To`	`Length`	`Description`	`FTId`
`SIGNAL`	`1 22`	`22`	`Potential.`
`CHAIN`	`23 577`	`555`	`Laccase-25.`	`PRO_0000291912`
`DOMAIN`	`30 147`	`118`	`Plastocyanin-like 1.`
`DOMAIN`	`158 313`	`156`	`Plastocyanin-like 2.`
`DOMAIN`	`423 560`	`138`	`Plastocyanin-like 3.`
`METAL`	`81 81`		`Copper 1 (By similarity).`
`METAL`	`83 83`		`Copper 2 (By similarity).`
`METAL`	`126 126`		`Copper 2 (By similarity).`
`METAL`	`128 128`		`Copper 3 (By similarity).`
`METAL`	`477 477`		`Copper 4 (By similarity).`
`METAL`	`480 480`		`Copper 1 (By similarity).`
`METAL`	`482 482`		`Copper 3 (By similarity).`
`METAL`	`539 539`		`Copper 3 (By similarity).`
`METAL`	`540 540`		`Copper 4 (By similarity).`
`METAL`	`541 541`		`Copper 2 (By similarity).`
`METAL`	`545 545`		`Copper 4 (By similarity).`
`CARBOHYD`	`33 33`		`N-linked (GlcNAc...) (Potential).`
`CARBOHYD`	`109 109`		`N-linked (GlcNAc...) (Potential).`
`CARBOHYD`	`169 169`		`N-linked (GlcNAc...) (Potential).`
`CARBOHYD`	`203 203`		`N-linked (GlcNAc...) (Potential).`
`CARBOHYD`	`208 208`		`N-linked (GlcNAc...) (Potential).`
`CARBOHYD`	`218 218`		`N-linked (GlcNAc...) (Potential).`
`CARBOHYD`	`332 332`		`N-linked (GlcNAc...) (Potential).`
`CARBOHYD`	`383 383`		`N-linked (GlcNAc...) (Potential).`
`CARBOHYD`	`396 396`		`N-linked (GlcNAc...) (Potential).`
`CARBOHYD`	`404 404`		`N-linked (GlcNAc...) (Potential).`
`CARBOHYD`	`441 441`		`N-linked (GlcNAc...) (Potential).`
`CARBOHYD`	`459 459`		`N-linked (GlcNAc...) (Potential).`

Sequence information

Length: 577 AA [This is the length of the unprocessed precursor]

Molecular weight: 63680 Da [This is the MW of the unprocessed precursor]

CRC64: CA6FE93780DD7AA1 [This is a checksum on the sequence]

        10         20         30         40         50         60 
MTLHWSLLLF IAIALVSSVA QAAVVEHTFN VGNFSISQLC QPPLIITAVN GQLPGPTIYA 

        70         80         90        100        110        120 
REGDTVVVHL VNTSPYSMTL HWHGVLQRGT PWADGPAMVT QCPVQPGGNY TYRFNVDGQE 

       130        140        150        160        170        180 
GTLWWHAHVS FHRATVYGAL VIRPRGGAKA YPFPKPDKEH VVILGEWWNA TVYDMERMAF 

       190        200        210        220        230        240 
LTGIPAPHAD AYTINGKPGD FYNCSAPNQT AKFEVRQNGT YLLRIINAGM NTPLFFKVAK 

       250        260        270        280        290        300 
HRLTVVGADA CYTKPYKTDV VVVSPGQTVD ALMVASAAVG RYYMAASPYD SAIPQGPPFS 

       310        320        330        340        350        360 
DTTATAILQY AGARRKTVRW RPPVLPRRPP VNDTATAHRF FSGMTALLRH GKPSAVPLAV 

       370        380        390        400        410        420 
DTHMYVTVGL GVSLCQPEQL LCNRSAPPVF SSSMNNASFV VPKNTSLLEA HFRREPAGVY 

       430        440        450        460        470        480 
TRDFPDTPPV VFDYTGDESD NATMQFTTKS TKVKTLRYNE TVEMVLQNTR LIAKESHPMH 

       490        500        510        520        530        540 
IHGFNFFILA QGFGNYDKRR AERRFNLVDP QERNTIAVPT GGWAVIRFVA DNPGMWYMHC 

       550        560        570 
HFDAHISLGL AMVLEVLDGP TPETSVPPPP ADLPRCS

Q0IP28 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools