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UniProtKB/Swiss-Prot entry Q0A8M5


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name PYRD_ALHEH
Primary accession number Q0A8M5
Secondary accession numbers None
Integrated into Swiss-Prot on May 20, 2008
Sequence was last modified on October 17, 2006 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 22)
Name and origin of the protein
Protein name Dihydroorotate dehydrogenase
Synonyms EC 1.3.3.1
Dihydroorotate oxidase
DHOdehase
DHODase
DHOD
Gene name
Name: pyrD
OrderedLocusNames: Mlg_1463
From
Alkalilimnicola ehrlichei (strain MLHE-1) [TaxID: 187272] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Chromatiales; Ectothiorhodospiraceae; Alkalilimnicola.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Sims D., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Oremland R.S., Hoeft S.E., Switzer-Blum J., Kulp T., King G., Tabita R., Witte B., Santini J.M., Basu P., Hollibaugh J.T., Xie G., Stolz J.F., Richardson P.;
"Complete sequence of Alkalilimnicola ehrilichei MLHE-1.";
Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CP000453; ABI56812.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_742302.1; -.
3D structure databases
ModBase Q0A8M5.
Ontologies
GO
GO:0005886; Cellular component: plasma membrane (inferred from electronic annotation from HAMAP).
GO:0004158; Molecular function: dihydroorotate oxidase activity (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00225; -; 1.
PBIL [Tree]
InterPro IPR013785; Aldolase_TIM.
IPR012135; DHO_DHase_1_2.
IPR005719; DHO_DHase_2.
IPR001295; Dihydroorotate_DHase_core.
Graphical view of domain structure.
Gene3D G3DSA:3.20.20.70; Aldolase_TIM; 1.
Pfam PF01180; DHO_dh; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000164; DHO_oxidase; 1.
TIGRFAMs TIGR01036; pyrD_sub2; 1.
PROSITE PS00911; DHODEHASE_1; 1.
PS00912; DHODEHASE_2; 1.
BLOCKS Q0A8M5.
Genome annotation databases
GeneID 4270244; -.
GenomeReviews CP000453_GR; Mlg_1463.
KEGG aeh:Mlg_1463; -.
NMPDR fig|187272.6.peg.1403; -.
Phylogenomic databases
HOGENOM Q0A8M5; -.
Genome annotation databases
CMR Q0A8M5; Mlg_1463.
Other
ProtoNet Q0A8M5.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Cell membrane; Complete proteome; Flavoprotein; FMN; Membrane; Oxidoreductase; Pyrimidine biosynthesis.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   340  340     Dihydroorotate dehydrogenase. PRO_0000336452
ACT_SITE   175   175        Nucleophile (By similarity). 
Sequence information
Length: 340 AA [This is the length of the unprocessed precursor] Molecular weight: 37191 Da [This is the MW of the unprocessed precursor] CRC64: BA1ED21D9836E4D7 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MYSLIRPLLM RMDAERSHEF SLAWMDRLAR LGLGRLLCGH RLPDMPRRVM GLTFANPVGL 

        70         80         90        100        110        120 
AAGLDKNGEH LEALGHVGFG FIEVGTVTPR PQPGNPEPRL FRLPAHEAII NRMGFNNQGV 

       130        140        150        160        170        180 
DALVQRLRVT RYQGVLGVNI GKNKDTPTER ATDDYLSCLQ KVYPYADYVA VNVSSPNTPG 

       190        200        210        220        230        240 
LRDLQGGELL EALLGRLTHL RGVLAREYGR YVPLVVKIAP DMDEAQRAHF CQQVLRYGID 

       250        260        270        280        290        300 
GVAATNTTLS RDGVEDDPLA REQGGLSGAP LRPRAQAVLE ELGQRLGHRV PLIGVGGIMS 

       310        320        330        340 
GADAQARMAA GADLLQIYSG FIYRGPLLLE ELLKAVAPEH 

Q0A8M5 in FASTA format

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BLAST logo BLAST submission on ExPASy/SIB
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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
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