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[1]
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NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=ATCC 38366 / 972;
DOI=10.1016/0378-1119(94)00705-W; PubMed=7828917 [NCBI, ExPASy, EBI, Israel, Japan]
Cavan G.,
Macdonald D.;
"Cloning and sequence of a gene encoding the pyruvate dehydrogenase E1 beta subunit of Schizosaccharomyces pombe.";
Gene 152:117-120(1995).
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[2]
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NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 38366 / 972;
DOI=10.1038/nature724; PubMed=11859360 [NCBI, ExPASy, EBI, Israel, Japan]
Wood V.,
Gwilliam R.,
Rajandream M.A.,
Lyne M.H.,
Lyne R.,
Stewart A.,
Sgouros J.G.,
Peat N.,
Hayles J.,
Baker S.G.,
Basham D.,
Bowman S.,
Brooks K.,
Brown D.,
Brown S.,
Chillingworth T.,
Churcher C.M.,
Collins M.,
Connor R., ![]()
Cronin A.,
Davis P.,
Feltwell T.,
Fraser A.,
Gentles S.,
Goble A.,
Hamlin N.,
Harris D.E.,
Hidalgo J.,
Hodgson G.,
Holroyd S.,
Hornsby T.,
Howarth S.,
Huckle E.J.,
Hunt S.,
Jagels K.,
James K.D.,
Jones L.,
Jones M.,
Leather S.,
McDonald S.,
McLean J.,
Mooney P.,
Moule S.,
Mungall K.L.,
Murphy L.D.,
Niblett D.,
Odell C.,
Oliver K.,
O'Neil S.,
Pearson D.,
Quail M.A.,
Rabbinowitsch E.,
Rutherford K.M.,
Rutter S.,
Saunders D.,
Seeger K.,
Sharp S.,
Skelton J.,
Simmonds M.N.,
Squares R.,
Squares S.,
Stevens K.,
Taylor K.,
Taylor R.G.,
Tivey A.,
Walsh S.V.,
Warren T.,
Whitehead S.,
Woodward J.R.,
Volckaert G.,
Aert R.,
Robben J.,
Grymonprez B.,
Weltjens I.,
Vanstreels E.,
Rieger M.,
Schaefer M.,
Mueller-Auer S.,
Gabel C.,
Fuchs M.,
Duesterhoeft A.,
Fritzc C.,
Holzer E.,
Moestl D.,
Hilbert H.,
Borzym K.,
Langer I.,
Beck A.,
Lehrach H.,
Reinhardt R.,
Pohl T.M.,
Eger P.,
Zimmermann W.,
Wedler H.,
Wambutt R.,
Purnelle B.,
Goffeau A.,
Cadieu E.,
Dreano S.,
Gloux S.,
Lelaure V.,
Mottier S.,
Galibert F.,
Aves S.J.,
Xiang Z.,
Hunt C.,
Moore K.,
Hurst S.M.,
Lucas M.,
Rochet M.,
Gaillardin C.,
Tallada V.A.,
Garzon A.,
Thode G.,
Daga R.R.,
Cruzado L.,
Jimenez J.,
Sanchez M.,
del Rey F.,
Benito J.,
Dominguez A.,
Revuelta J.L.,
Moreno S.,
Armstrong J.,
Forsburg S.L.,
Cerutti L.,
Lowe T.,
McCombie W.R.,
Paulsen I.,
Potashkin J.,
Shpakovski G.V.,
Ussery D.,
Barrell B.G.,
Nurse P.;
"The genome sequence of Schizosaccharomyces pombe.";
Nature 415:871-880(2002).
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- FUNCTION: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
- CATALYTIC ACTIVITY: Pyruvate + [dihydrolipoyllysine-residue acetyltransferase] lipoyllysine = [dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine + CO2.
- COFACTOR: Thiamine pyrophosphate.
- SUBUNIT: Tetramer of 2 alpha and 2 beta subunits.
- SUBCELLULAR LOCATION: Mitochondrion matrix.
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Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms.
Distributed under the Creative Commons Attribution-NoDerivs License.
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| Length: 366 AA [This is the length of the unprocessed precursor] |
Molecular weight: 39624 Da [This is the MW of the unprocessed precursor] |
CRC64: 5835A6872F6EDC0A [This is a checksum on the sequence] |
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10 20 30 40 50 60
MIRLQKFGEI VGTSRSWKLL SSTIAKRYSS SSNGVKEMTV RDALNSAMEE EMKRDDRVFL
70 80 90 100 110 120
IGEEVAQYNG AYKISRGLLD KFGPKRVIDT PITEMGFTGL ATGAAFAGLR PICEFMTFNF
130 140 150 160 170 180
SMQAIDHIVN SAARTLYMSG GIQACPIVFR GPNGPAAAVA AQHSQHFAPW YGSIPGLKVV
190 200 210 220 230 240
SPYSAEDARG LLKAAIRDPN PVVVLENEIL YGKTFPISKE ALSEDFVLPF GLAKVERPGK
250 260 270 280 290 300
DITIVGESIS VVTALEAADK LKADYGVEAE VINLRSIRPL DINTIAASVK KTNRIVTVDQ
310 320 330 340 350 360
AYSQHGIGSE IAAQIMESDA FDYLDAPVER VSMADVPMPY SHPVEAASVP NADVVVAAAK
KCLYIK
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Q09171 in FASTA format |
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