ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!
Search for

UniProtKB/Swiss-Prot entry Q03TT0


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

Note: most headings are clickable, even if they don't appear as links. They link to the user manual or other documents.
Entry information
Entry name GUAC_LACBA
Primary accession number Q03TT0
Secondary accession numbers None
Integrated into Swiss-Prot on June 26, 2007
Sequence was last modified on November 14, 2006 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 16)
Name and origin of the protein
Protein name GMP reductase
Synonyms EC 1.7.1.7
Guanosine 5'-monophosphate oxidoreductase
Guanosine monophosphate reductase
Gene name
Name: guaC
OrderedLocusNames: LVIS_0226
From
Lactobacillus brevis (strain ATCC 367 / JCM 1170) [TaxID: 387344] [HAMAP proteome]
Taxonomy Bacteria; Firmicutes; Lactobacillales; Lactobacillaceae; Lactobacillus.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1073/pnas.0607117103; PubMed=17030793 [NCBI, ExPASy, EBI, Israel, Japan]
Makarova K.S., Slesarev A., Wolf Y.I., Sorokin A., Mirkin B., Koonin E.V., Pavlov A., Pavlova N., Karamychev V., Polouchine N., Shakhova V., Grigoriev I., Lou Y., Rohksar D., Lucas S., Huang K., Goodstein D.M., Hawkins T., Plengvidhya V., Welker D., Hughes J., Goh Y., Benson A., Baldwin K., Lee J.-H., Diaz-Muniz I., Dosti B., Smeianov V., Wechter W., Barabote R., Lorca G., Altermann E., Barrangou R., Ganesan B., Xie Y., Rawsthorne H., Tamir D., Parker C., Breidt F., Broadbent J.R., Hutkins R., O'Sullivan D., Steele J., Unlu G., Saier M.H. Jr., Klaenhammer T., Richardson P., Kozyavkin S., Weimer B.C., Mills D.A.;
"Comparative genomics of the lactic acid bacteria.";
Proc. Natl. Acad. Sci. U.S.A. 103:15611-15616(2006).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CP000416; ABJ63392.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_794423.1; -.
3D structure databases
ModBase Q03TT0.
Ontologies
GO
GO:0003920; Molecular function: GMP reductase activity (inferred from electronic annotation from HAMAP).
GO:0006163; Biological process: purine nucleotide metabolic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_01511; -; 1.
PBIL [Tree]
InterPro IPR013785; Aldolase_TIM.
IPR005994; GMP_reduct2.
IPR015875; IMP_DH/GMP_Rdtase_CS.
IPR001093; IMP_DHase_GMPRtase.
Graphical view of domain structure.
Gene3D G3DSA:3.20.20.70; Aldolase_TIM; 1.
Pfam PF00478; IMPDH; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF036500; GMP_red_Firmic; 1.
TIGRFAMs TIGR01306; GMP_reduct_2; 1.
PROSITE PS00487; IMP_DH_GMP_RED; 1.
BLOCKS Q03TT0.
Genome annotation databases
GeneID 4413048; -.
GenomeReviews CP000416_GR; LVIS_0226.
KEGG lbr:LVIS_0226; -.
NMPDR fig|387344.8.peg.218; -.
Phylogenomic databases
HOGENOM Q03TT0; -.
Genome annotation databases
CMR Q03TT0; LVIS_0226.
Other
ProtoNet Q03TT0.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; NADP; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   328  328     GMP reductase. PRO_0000292050
NP_BIND   206   229  24     NADP (Potential). 
ACT_SITE   177   177        Thioimidate intermediate (By similarity). 
Sequence information
Length: 328 AA [This is the length of the unprocessed precursor] Molecular weight: 36006 Da [This is the MW of the unprocessed precursor] CRC64: DD7A0C66BF41F14B [This is a checksum on the sequence]
        10         20         30         40         50         60 
MHPAEVFDYE DIQLVPNKCI IDSRSEADTS IEFGPRRFKI PVVPANMETV INEPLAVWLA 

        70         80         90        100        110        120 
EHDYFYVMHR FQPEDRRGFI ERMQAKSLFA SISVGVKPEE VTFIDELATA GLTPEYITID 

       130        140        150        160        170        180 
IAHGHSDAVI RMIHHIKQQL PNSFVIAGNV GTPEAVRELE NAGADATKVG IGPGKACITK 

       190        200        210        220        230        240 
LKTGFGTGGW QLAAVRLCAK AARKPIVADG GIRYNGDIAK SIRFGASMVM IGSMLAGHEQ 

       250        260        270        280        290        300 
SPGSLLTIDG RTFKQYWGSA SEKQKGAYRN VEGKQMLVPY RGDIDQTLTA MEEDLQSAIS 

       310        320 
YAGGRNLLDI RTVDYVIVKS SILNGDNY 

Q03TT0 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

BLAST logo BLAST submission on ExPASy/SIB
or at NCBI (USA)
Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
 Hosted by kr flag YPRC Korea Mirror sites: Australia  Brazil  Canada  China  Switzerland
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!