[1]	NUCLEOTIDE SEQUENCE [MRNA]. STRAIN=cv. Columbia; PubMed=2606345 [NCBI, ExPASy, EBI, Israel, Japan] Sharrock R.A., Quail P.H.; "Novel phytochrome sequences in Arabidopsis thaliana: structure, evolution, and differential expression of a plant regulatory photoreceptor family."; Genes Dev. 3:1745-1757(1989).
[2]	NUCLEOTIDE SEQUENCE [GENOMIC DNA]. DOI=10.1104/pp.106.2.813; PubMed=7991704 [NCBI, ExPASy, EBI, Israel, Japan] Cowl J.S., Hartley N., Xie D., Whitelam G.C., Murphy G., Harberd N.P.; "The PHYC gene of Arabidopsis. Absence of the third intron found in PHYA and PHYB."; Plant Physiol. 106:813-814(1994).
[3]	NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. STRAIN=cv. Columbia; DOI=10.1093/dnares/4.3.215; PubMed=9330910 [NCBI, ExPASy, EBI, Israel, Japan] Sato S., Kotani H., Nakamura Y., Kaneko T., Asamizu E., Fukami M., Miyajima N., Tabata S.; "Structural analysis of Arabidopsis thaliana chromosome 5. I. Sequence features of the 1.6 Mb regions covered by twenty physically assigned P1 clones."; DNA Res. 4:215-230(1997).

Comments

FUNCTION: Regulatory photoreceptor which exists in two forms that are reversibly interconvertible by light: the Pr form that absorbs maximally in the red region of the spectrum and the Pfr form that absorbs maximally in the far-red region. Photoconversion of Pr to Pfr induces an array of morphogenic responses, whereas reconversion of Pfr to Pr cancels the induction of those responses. Pfr controls the expression of a number of nuclear genes including those encoding the small subunit of ribulose-bisphosphate carboxylase, chlorophyll A/B binding protein, protochlorophyllide reductase, rRNA, etc. It also controls the expression of its own gene(s) in a negative feedback fashion.
SUBUNIT: Homodimer.
INTERACTION:
P14713:PHYB; NbExp=1; IntAct=EBI-624366, EBI-300727;
PTM: Contains one covalently linked phytochromobilin chromophore (By similarity).
SIMILARITY: Belongs to the phytochrome family.
SIMILARITY: Contains 1 GAF domain.
SIMILARITY: Contains 1 histidine kinase domain.
SIMILARITY: Contains 1 PAC (PAS-associated C-terminal) domain.
SIMILARITY: Contains 2 PAS (PER-ARNT-SIM) domains.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

X17343; CAA35223.1; -; mRNA.	[EMBL / GenBank / DDBJ] [CoDingSequence]
Z32538; CAA83549.1; -; Genomic_DNA.	[EMBL / GenBank / DDBJ] [CoDingSequence]
AB005236; BAB09925.1; -; Genomic_DNA.	[EMBL / GenBank / DDBJ] [CoDingSequence]

C33473; FKMUC.

NP_198433.1; -.

3D structure databases

ModBase

P14714.

Protein-protein interaction databases

IntAct

P14714; -.

Organism-specific databases

TAIR

At5g35840; -.

Gene expression databases

ArrayExpress

P14714; -.

GermOnline

AT5G35840; Arabidopsis thaliana.

Ontologies

GO:0005515;	Molecular function: protein binding (inferred from physical interaction from IntAct).
QuickGo view.

Family and domain databases

InterPro

IPR003594; ATP_bd_ATPase.
IPR003018; GAF.
IPR001610; PAC.
IPR000014; PAS.
IPR013654; PAS_2.
IPR013767; PAS_fold.
IPR016132; Phyto_chromo_attachment.
IPR013516; Phyto_chromo_BS.
IPR001294; Phytochrome.
IPR012129; Phytochrome_A-E.
IPR013515; Phytochrome_Cr.
IPR003661; Sig_transdc_His_kin_sub1_dim/P.
IPR005467; Sig_transdc_His_kinase_core.
Graphical view of domain structure.

Gene3D

G3DSA:3.30.565.10; ATP_bd_ATPase; 1.

Pfam

PF01590; GAF; 1.
PF02518; HATPase_c; 1.
PF00989; PAS; 2.
PF08446; PAS_2; 1.
PF00360; Phytochrome; 1.
Pfam graphical view of domain structure.

PIRSF

PIRSF000084; Phytochrome; 1.

PRINTS

PR01033; PHYTOCHROME.

SMART

SM00065; GAF; 1.
SM00387; HATPase_c; 1.
SM00388; HisKA; 1.
SM00086; PAC; 1.
SM00091; PAS; 2.
SMART graphical view of domain structure.

TIGRFAMs

TIGR00229; sensory_box; 1.

PROSITE

PS50109; HIS_KIN; 1.
PS50112; PAS; 2.
PS00245; PHYTOCHROME_1; 1.
PS50046; PHYTOCHROME_2; 1.
PROSITE graphical view of domain structure (profiles).

Genome annotation databases

GeneID

833570; -.

GenomeReviews

BA000015_GR; AT5G35840.

KEGG

ath:AT5G35840; -.

NMPDR

fig|3702.1.peg.25291; -.

Other

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Chromophore; Complete proteome; Photoreceptor protein; Receptor; Repeat; Sensory transduction; Transcription; Transcription regulation.

Features

Feature table viewer

Feature aligner

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 1111`	`1111`	`Phytochrome C.`	`PRO_0000171964`
`DOMAIN`	`213 393`	`181`	`GAF.`
`DOMAIN`	`604 674`	`71`	`PAS 1.`
`DOMAIN`	`737 808`	`72`	`PAS 2.`
`DOMAIN`	`889 1111`	`223`	`Histidine kinase.`
`BINDING`	`318 318`		`Phytochromobilin chromophore (covalent; via 1 link) (By similarity).`
`CONFLICT`	`9 9`		`C -> Y (in Ref. 2; CAA83549).`
`CONFLICT`	`137 137`		`E -> Q (in Ref. 2; CAA83549).`
`CONFLICT`	`230 230`		`G -> S (in Ref. 2; CAA83549).`
`CONFLICT`	`446 446`		`N -> K (in Ref. 2; CAA83549).`
`CONFLICT`	`505 505`		`S -> T (in Ref. 2; CAA83549).`
`CONFLICT`	`726 726`		`T -> K (in Ref. 2; CAA83549).`
`CONFLICT`	`735 735`		`K -> Q (in Ref. 2; CAA83549).`
`CONFLICT`	`754 754`		`I -> M (in Ref. 2; CAA83549).`
`CONFLICT`	`822 822`		`E -> K (in Ref. 2; CAA83549).`
`CONFLICT`	`1017 1018`		`LR -> WK (in Ref. 2; CAA83549).`

Sequence information

Length: 1111 AA [This is the length of the unprocessed precursor]

Molecular weight: 123722 Da [This is the MW of the unprocessed precursor]

CRC64: 58FE4645501135CA [This is a checksum on the sequence]

        10         20         30         40         50         60 
MSSNTSRSCS TRSRQNSRVS SQVLVDAKLH GNFEESERLF DYSASINLNM PSSSCEIPSS 

        70         80         90        100        110        120 
AVSTYLQKIQ RGMLIQPFGC LIVVDEKNLK VIAFSENTQE MLGLIPHTVP SMEQREALTI 

       130        140        150        160        170        180 
GTDVKSLFLS PGCSALEKAV DFGEISILNP ITLHCRSSSK PFYAILHRIE EGLVIDLEPV 

       190        200        210        220        230        240 
SPDEVPVTAA GALRSYKLAA KSISRLQALP SGNMLLLCDA LVKEVSELTG YDRVMVYKFH 

       250        260        270        280        290        300 
EDGHGEVIAE CCREDMEPYL GLHYSATDIP QASRFLFMRN KVRMICDCSA VPVKVVQDKS 

       310        320        330        340        350        360 
LSQPISLSGS TLRAPHGCHA QYMSNMGSVA SLVMSVTING SDSDEMNRDL QTGRHLWGLV 

       370        380        390        400        410        420 
VCHHASPRFV PFPLRYACEF LTQVFGVQIN KEAESAVLLK EKRILQTQSV LCDMLFRNAP 

       430        440        450        460        470        480 
IGIVTQSPNI MDLVKCDGAA LYYRDNLWSL GVTPTETQIR DLIDWVLKSH GGNTGFTTES 

       490        500        510        520        530        540 
LMESGYPDAS VLGESICGMA AVYISEKDFL FWFRSSTAKQ IKWGGARHDP NDRDGKRMHP 

       550        560        570        580        590        600 
RSSFKAFMEI VRWKSVPWDD MEMDAINSLQ LIIKGSLQEE HSKTVVDVPL VDNRVQKVDE 

       610        620        630        640        650        660 
LCVIVNEMVR LIDTAAVPIF AVDASGVING WNSKAAEVTG LAVEQAIGKP VSDLVEDDSV 

       670        680        690        700        710        720 
ETVKNMLALA LEGSEERGAE IRIRAFGPKR KSSPVELVVN TCCSRDMTNN VLGVCFIGQD 

       730        740        750        760        770        780 
VTGQKTLTEN YSRVKGDYAR IMWSPSTLIP PIFITNENGV CSEWNNAMQK LSGIKREEVV 

       790        800        810        820        830        840 
NKILLGEVFT TDDYGCCLKD HDTLTKLRIG FNAVISGQKN IEKLLFGFYH RDGSFIEALL 

       850        860        870        880        890        900 
SANKRTDIEG KVTGVLCFLQ VPSPELQYAL QVQQISEHAI ACALNKLAYL RHEVKDPEKA 

       910        920        930        940        950        960 
ISFLQDLLHS SGLSEDQKRL LRTSVLCREQ LAKVISDSDI EGIEEGYVEL DCSEFGLQES 

       970        980        990       1000       1010       1020 
LEAVVKQVME LSIERKVQIS CDYPQEVSSM RLYGDNLRLQ QILSETLLSS IRFTPALRGL 

      1030       1040       1050       1060       1070       1080 
CVSFKVIARI EAIGKRMKRV ELEFRIIHPA PGLPEDLVRE MFQPLRKGTS REGLGLHITQ 

      1090       1100       1110 
KLVKLMERGT LRYLRESEMS AFVILTEFPL I

P14714 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools