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UniProtKB/Swiss-Prot entry P94462


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name DEF1_BACSU
Primary accession number P94462
Secondary accession numbers None
Integrated into Swiss-Prot on November 1, 1997
Sequence was last modified on May 1, 1997 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 65)
Name and origin of the protein
Protein name Peptide deformylase 1
Synonyms PDF 1
EC 3.5.1.88
Polypeptide deformylase 1
Gene name
Name: defA
Synonyms: def, yloK
OrderedLocusNames: BSU15720
From
Bacillus subtilis [TaxID: 1423] [HAMAP proteome]
Taxonomy Bacteria; Firmicutes; Bacillales; Bacillaceae; Bacillus.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=168;
DOI=10.1006/jmbi.1996.0835; PubMed=9086272 [NCBI, ExPASy, EBI, Israel, Japan]
Mazel D., Coic E., Blanchard S., Saurin W., Marliere P.;
"A survey of polypeptide deformylase function throughout the eubacterial lineage.";
J. Mol. Biol. 266:939-949(1997).
[2]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=168;
PubMed=9534248 [NCBI, ExPASy, EBI, Israel, Japan]
Foulger D., Errington J.;
"A 28 kbp segment from the spoVM region of the Bacillus subtilis 168 genome.";
Microbiology 144:801-805(1998).
[3]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=168;
DOI=10.1038/36786; PubMed=9384377 [NCBI, ExPASy, EBI, Israel, Japan]
Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S., Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K., Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F., Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D., Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M., Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P., Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K., Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S., Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y., Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G., Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J., Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C., Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S., Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B., Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S., Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M., Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y., Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J., Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A., Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M., Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S., Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E., Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K., Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E., Yoshikawa H., Danchin A.;
"The complete genome sequence of the Gram-positive bacterium Bacillus subtilis.";
Nature 390:249-256(1997).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
Y10304; CAA71349.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
Y13937; CAA74262.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
Z99112; CAB13445.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR F69613; F69613.
RefSeq NP_389454.1; -.
3D structure databases
HSSP P27251; 1DEF. [HSSP ENTRY / PDB]
ModBase P94462.
Enzyme and pathway databases
BioCyc BSUB224308:BSU1573-MON; -.
Organism-specific databases
SubtiList BG11933; def. [Micado]
Ontologies
GO
GO:0005506; Molecular function: iron ion binding (inferred from electronic annotation from InterPro).
GO:0042586; Molecular function: peptide deformylase activity (inferred from electronic annotation from HAMAP).
GO:0006412; Biological process: translation (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00163; -; 1.
PBIL [Tree]
InterPro IPR000181; Fmet_deformylase.
Graphical view of domain structure.
Gene3D G3DSA:3.90.45.10; Fmet_deformylase; 1.
PANTHER PTHR10458; Fmet_deformylase; 1.
Pfam PF01327; Pep_deformylase; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF004749; Pep_def; 1.
PRINTS PR01576; PDEFORMYLASE.
ProDom PD003844; Fmet_deformylase; 1.
[Domain structure / List of seq. sharing at least 1 domain]
TIGRFAMs TIGR00079; pept_deformyl; 1.
ProtoNet P94462.
Genome annotation databases
GeneID 938819; -.
GenomeReviews AL009126_GR; BSU15720.
KEGG bsu:BSU15720; -.
NMPDR fig|224308.1.peg.1574; -.
Phylogenomic databases
HOGENOM P94462; -.
Genome annotation databases
CMR P94462; BSU15720.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Hydrolase; Iron; Metal-binding; Protein biosynthesis.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   160  160     Peptide deformylase 1. PRO_0000082739
ACT_SITE   133   133        By similarity. 
METAL   90    90        Iron (By similarity). 
METAL   132   132        Iron (By similarity). 
METAL   136   136        Iron (By similarity). 
Sequence information
Length: 160 AA [This is the length of the unprocessed precursor] Molecular weight: 17775 Da [This is the MW of the unprocessed precursor] CRC64: C73DBC266FDD98FC [This is a checksum on the sequence]
        10         20         30         40         50         60 
MAVKKVVTHP AEVLETPAET VTVFDKKLKK LLDDMYDTML EMDGVGLAAP QIGILKRAAV 

        70         80         90        100        110        120 
VEIGDDRGRI DLVNPEILEK SGEQTGIEGC LSFPNVYGDV TRADYVKVRA FNRQGKPFIL 

       130        140        150        160 
EARGFLARAV QHEMDHLDGV LFTSKISKYY TEDELADMEG 

P94462 in FASTA format

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BLAST logo BLAST submission on ExPASy/SIB
or at NCBI (USA)
Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

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