ID   DHE3_SOLLC              Reviewed;         412 AA.
AC   P93541;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1997, sequence version 1.
DT   25-NOV-2008, entry version 59.
DE   RecName: Full=Glutamate dehydrogenase;
DE            Short=GDH;
DE            EC=1.4.1.3;
DE   AltName: Full=Legdh1;
GN   Name=GDH1;
OS   Solanum lycopersicum (Tomato) (Lycopersicon esculentum).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliophyta; eudicotyledons; core eudicotyledons;
OC   asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae;
OC   Solanum; Lycopersicon.
OX   NCBI_TaxID=4081;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=cv. Pera;
RX   MEDLINE=97228425; PubMed=9074503; DOI=10.1016/S0378-1119(96)00716-0;
RA   Purnell M.P., Stewart G.R., Botella J.R.;
RT   "Cloning and characterisation of a glutamate dehydrogenase cDNA from
RT   tomato (Lycopersicon esculentum L.).";
RL   Gene 186:249-254(1997).
CC   -!- CATALYTIC ACTIVITY: L-glutamate + H(2)O + NAD(P)(+) = 2-
CC       oxoglutarate + NH(3) + NAD(P)H.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion matrix (Potential).
CC   -!- TISSUE SPECIFICITY: In roots, stems, leaves and flowers but not in
CC       fruits.
CC   -!- SIMILARITY: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
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DR   EMBL; U48695; AAB39508.1; -; mRNA.
DR   PIR; JC6317; JC6317.
DR   UniGene; Les.20253; -.
DR   HSSP; P96110; 1B26.
DR   GO; GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
DR   GO; GO:0005488; F:binding; IEA:InterPro.
DR   GO; GO:0004353; F:glutamate dehydrogenase [NAD(P)+] activity; IEA:EC.
DR   GO; GO:0006520; P:amino acid metabolic process; IEA:InterPro.
DR   GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW.
DR   InterPro; IPR006095; Glu/Leu/Phe/Val_DHase.
DR   InterPro; IPR006096; Glu/Leu/Phe/Val_DHase_C.
DR   InterPro; IPR006097; Glu/Leu/Phe/Val_DHase_dimer.
DR   InterPro; IPR014362; Glu_DHase.
DR   InterPro; IPR016040; NAD(P)-bd.
DR   Gene3D; G3DSA:3.40.50.720; NAD(P)-bd; 1.
DR   PANTHER; PTHR11606:SF2; GLFV_DH; 1.
DR   Pfam; PF00208; ELFV_dehydrog; 1.
DR   Pfam; PF02812; ELFV_dehydrog_N; 1.
DR   PIRSF; PIRSF000185; Glu_DH; 1.
DR   PRINTS; PR00082; GLFDHDRGNASE.
DR   PROSITE; PS00074; GLFV_DEHYDROGENASE; 1.
PE   2: Evidence at transcript level;
KW   Mitochondrion; NAD; Oxidoreductase.
FT   CHAIN         1    412       Glutamate dehydrogenase.
FT                                /FTId=PRO_0000182748.
FT   ACT_SITE    102    102       By similarity.
SQ   SEQUENCE   412 AA;  44813 MW;  83BC4138047A6BCA CRC64;
     MNALAATNRN FKLAARLLGL DSKLELSLLI PFREIKVECT IPKDDGTLAS FVGFRVQHDN
     ARGPMKGGIR YHPEVDPDEV NALAQLMTWK TAVANIPYGG AKGGIGCSPS DLSISELERL
     TRVFTQKIHD LIGIHTDVPA PDMGTNPQTM AWILDEYSKF HGYSPAVVTG KPVDLGGSLG
     RDAATGRGAL FATEALLNEH GKSVAGQRFV IQGFGNVGSW AAKLIHEQGG KVVAVSDITG
     AIKNEKGIDI ESLFKHVKET RGVKGFHDAH PIDANSILVE DCDVLIPAAL GGVINKDNHK
     LKIKAKYIIE AANHPTDPEA DEILSKKGVT ILPDIYANSG GVTVSYFEWV QNIQGFMWDE
     KKVNDELKTY MTRGFKDVKD MCKTHNCDLR MGAFTLGVNR VARATVLRGW EA
//