[1]	PROTEIN SEQUENCE, CATALYTIC ACTIVITY, BIOPHYSICOCHEMICAL PROPERTIES, AND GLYCOSYLATION. Janusz G., Rogalski J.M.; "Purification of Cerrena unicolor laccase."; Submitted (APR-2007) to UniProtKB.

Comments

FUNCTION: Lignin degradation and detoxification of lignin-derived products (Probable).
CATALYTIC ACTIVITY: 4 benzenediol + O₂ = 4 benzosemiquinone + 2 H₂O.
COFACTOR: Binds 4 copper ions per monomer (By similarity).
BIOPHYSICOCHEMICAL PROPERTIES:

Kinetic parameters:   K_M=0.166 mM for syringaldazine;
pH dependence:   Optimum pH is 5.3;
Temperature dependence:   Optimum temperature is 60 degrees Celsius;
SUBCELLULAR LOCATION: Secreted (By similarity).
PTM: Glycosylated; contains 8.47% carbohydrates.
MISCELLANEOUS: On the 2D-gel the determined pI of this protein is: 4.56, its MW is: 62.03 kDa.
SIMILARITY: Belongs to the multicopper oxidase family.

Copyright

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Cross-references

3D structure databases
ModBase	P85149.
Family and domain databases
InterPro	IPR002355; Cu_oxidase_Cu_BS. Graphical view of domain structure.
PROSITE	PS00079; MULTICOPPER_OXIDASE1; PARTIAL. PS00080; MULTICOPPER_OXIDASE2; PARTIAL.
BLOCKS	P85149.
Other
ProtoNet	P85149.
UniRef	View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Copper; Direct protein sequencing; Glycoprotein; Lignin degradation; Metal-binding; Oxidoreductase; Secreted.

Features

Feature table viewer

Sequence information

Length: 10 AA [This is the length of the partial sequence of the unprocessed precursor]

Molecular weight: 1005 Da [This is the MW of the partial sequence of the unprocessed precursor]

CRC64: 212CE22AADC2D768 [This is a checksum on the sequence]

        10 
AIGPVADLHI

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools