Alpha-AASA dehydrogenase
EC 1.2.1.31
Delta1-piperideine-6-carboxylate dehydrogenease
P6c dehydrogenase
Aldehyde dehydrogenase family 7 member A1
Antiquitin-1

Gene name

Name:

aldh7a1

From

Ctenopharyngodon idella (Grass carp)

[TaxID: 7959]

Taxonomy

Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Cyprinidae; Ctenopharyngodon.

Protein existence

1: Evidence at protein level;

References

[1]

PROTEIN SEQUENCE, CATALYTIC ACTIVITY, BIOPHYSICOCHEMICAL PROPERTIES, AND SUBUNIT.
TISSUE=Liver;
DOI=10.1016/S1096-4959(03)00248-3; PubMed=14602152 [NCBI, ExPASy, EBI, Israel, Japan]
Chan W.-M., Tang W.-K., Cheng C.H., Fong W.-P.;
"Purification, N-terminal sequence determination and enzymatic characterization of antiquitin from the liver of grass carp.";
Comp. Biochem. Physiol. 136B:443-450(2003).

Comments

CATALYTIC ACTIVITY: L-2-aminoadipate 6-semialdehyde + NAD(P)⁺ + H₂O = L-2-aminoadipate + NAD(P)H.
BIOPHYSICOCHEMICAL PROPERTIES:

Kinetic parameters: K_M=2.0 mM for acetaldehyde;
V_max=1.95 µmol/min/mg enzyme;
pH dependence: Optimum pH is 9-10;
SUBUNIT: Homotetramer.
SIMILARITY: Belongs to the aldehyde dehydrogenase family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

3D structure databases
ModBase	P84463.
Family and domain databases
InterPro	IPR016160; Ald_DHase_CS. Graphical view of domain structure.
PROSITE	PS00070; ALDEHYDE_DEHYDR_CYS; PARTIAL. PS00687; ALDEHYDE_DEHYDR_GLU; PARTIAL.
BLOCKS	P84463.
Phylogenomic databases
HOVERGEN	P84463; -.
Other
ProtoNet	P84463.
UniRef	View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Direct protein sequencing; NAD; Oxidoreductase.

Features

Feature table viewer

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 >21`	`>21`	`Alpha-aminoadipic semialdehyde dehydrogenase.`	`PRO_0000056494`
`NON_TER`	`21 21`

Sequence information

Length: 21 AA [This is the length of the partial sequence of the unprocessed precursor]

Molecular weight: 2289 Da [This is the MW of the partial sequence of the unprocessed precursor]

CRC64: A69E54BB27B2EF1A [This is a checksum on the sequence]

        10         20 
SALAINQPNY SVLKELGLNE D

P84463 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
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	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools