[1]	PROTEIN SEQUENCE, COFACTOR, AND ENZYME REGULATION. TISSUE=Kidney; Schweiger M., Wissler J.H., Amselgruber W.M.; "Xylitol:NAD 2-oxidoreductase (D-xylulose reductase EC 1.1.1.9) from porcine kidney. Purification and properties."; Submitted (JUL-2001) to UniProtKB.

Comments

CATALYTIC ACTIVITY: Xylitol + NAD⁺ = D-xylulose + NADH.
ENZYME REGULATION: Activated by calcium and inhibited by zinc.
SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

3D structure databases

ModBase

P83049.

Ontologies

GO:0046526;	Molecular function: D-xylulose reductase activity (inferred from electronic annotation from EC).
QuickGo view.

Family and domain databases

InterPro

IPR002328; AlcDHase_Zn_CS.
Graphical view of domain structure.

PROSITE

PS00059; ADH_ZINC; PARTIAL.

BLOCKS

P83049.

Phylogenomic databases

HOVERGEN

P83049; -.

Other

ProtoNet

P83049.

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Carbohydrate metabolism; Direct protein sequencing; Metal-binding; NAD; Oxidoreductase; Xylose metabolism; Zinc.

Features

Feature table viewer

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 >134`	`>134`	`D-xylulose reductase.`	`PRO_0000160882`
`NON_CONS`	`21 22`
`NON_CONS`	`37 38`
`NON_CONS`	`44 45`
`NON_CONS`	`55 56`
`NON_CONS`	`68 69`
`NON_CONS`	`76 77`
`NON_CONS`	`80 81`
`NON_CONS`	`92 93`
`NON_CONS`	`110 111`
`NON_CONS`	`128 129`
`NON_TER`	`134 134`

Sequence information

Length: 134 AA [This is the length of the partial sequence of the unprocessed precursor]

Molecular weight: 14858 Da [This is the MW of the partial sequence of the unprocessed precursor]

CRC64: 540FC39ADDBFB5DA [This is a checksum on the sequence]

        10         20         30         40         50         60 
XXKLVESGXX LVQPGGSLRL SKXYTENVNH PATTTXYKXQ PMTPDFTEXQ THEGTHQDVF 

        70         80         90        100        110        120 
DQPNLXXWKG NTLPEGYEPA KXGEXGTQDA NPKXXQDGDE XTXTGXXQXD KIGRYNLXPT 

       130 
IFFEATPPKA NENQ

P83049 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools