[1]	PROTEIN SEQUENCE. TISSUE=Heart, and Liver; PubMed=9310366 [NCBI, ExPASy, EBI, Israel, Japan] Arnold S., Lee I., Kim M., Song E., Linder D., Lottspeich F., Kadenbach B.; "The subunit structure of cytochrome-c oxidase from tuna heart and liver."; Eur. J. Biochem. 248:99-103(1997).

Comments

FUNCTION: This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.
CATALYTIC ACTIVITY: 4 ferrocytochrome c + O₂ + 4 H⁺ = 4 ferricytochrome c + 2 H₂O.
SUBCELLULAR LOCATION: Mitochondrion inner membrane.
SIMILARITY: Belongs to the cytochrome c oxidase Vb family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases
PIR	S77983; S77983.
3D structure databases
ModBase	P80974.
Family and domain databases
InterPro	IPR002124; COX5B. Graphical view of domain structure.
PROSITE	PS00848; COX5B_1; PARTIAL.
BLOCKS	P80974.
Phylogenomic databases
HOVERGEN	P80974; -.
Other
ProtoNet	P80974.
UniRef	View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Direct protein sequencing; Membrane; Mitochondrion; Mitochondrion inner membrane; Oxidoreductase.

Features

Feature table viewer

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 >20`	`>20`	`Cytochrome c oxidase polypeptide Vb.`	`PRO_0000197032`
`NON_TER`	`20 20`

Sequence information

Length: 20 AA [This is the length of the partial sequence of the unprocessed precursor]

Molecular weight: 2158 Da [This is the MW of the partial sequence of the unprocessed precursor]

CRC64: 76F1473E1F392BD7 [This is a checksum on the sequence]

        10         20 
GTLKGIPTDD EQATGLERRT

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools