ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!
Search for

UniProtKB/Swiss-Prot entry P80534

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

Note: most headings are clickable, even if they don't appear as links. They link to the user manual or other documents.
Entry information
Entry name G3P1_JACOR
Primary accession number P80534
Secondary accession number Q64418
Integrated into Swiss-Prot on February 1, 1996
Sequence was last modified on November 1, 1997 (Sequence version 2)
Annotations were last modified on    July 22, 2008 (Entry version 54)
Name and origin of the protein
Protein name Glyceraldehyde-3-phosphate dehydrogenase, muscle
Synonyms GAPDH
EC 1.2.1.12
Gene name None
From
Jaculus orientalis (Greater Egyptian jerboa) [TaxID: 48868] 
Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Dipodidae; Dipodinae; Jaculus.
Protein existence 1: Evidence at protein level;
References
[1]
 PROTEIN SEQUENCE OF 1-54.
TISSUE=Skeletal muscle;
Soukri A., Serrano A.;
Submitted (JAN-1996) to UniProtKB.
[2]
 NUCLEOTIDE SEQUENCE [MRNA] OF 25-363.
TISSUE=Skeletal muscle;
DOI=10.1016/S0378-1119(96)00494-5; PubMed=8973322 [NCBI, ExPASy, EBI, Israel, Japan]
Soukri A., Valverde F., Hafid N., Elkebbaj M.S., Serrano A.;
"Occurrence of a differential expression of the glyceraldehyde-3-phosphate dehydrogenase gene in muscle and liver from euthermic and induced hibernating jerboa (Jaculus orientalis).";
Gene 181:139-145(1996).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
X87226; CAA60678.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR JC5370; JC5370.
3D structure databases
HSSP P00354; 3GPD. [HSSP ENTRY / PDB]
SMR P80534; 31-363.
ModBase P80534.
Family and domain databases
InterPro IPR000173; GlycerAld_3-P_DHase.
IPR006424; Glyceraldehyde-3-P_DHase_1.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
PANTHER PTHR10836; GAP_DH; 1.
Pfam PF02800; Gp_dh_C; 1.
PF00044; Gp_dh_N; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000149; GAP_DH; 1.
PRINTS PR00078; G3PDHDRGNASE.
TIGRFAMs TIGR01534; GAPDH-I; 1.
PROSITE PS00071; GAPDH; 1.
BLOCKS P80534.
Phylogenomic databases
HOVERGEN P80534; -.
Other
ProtoNet P80534.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
ADP-ribosylation; Cytoplasm; Direct protein sequencing; Glycolysis; NAD; Oxidoreductase; S-nitrosylation.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
INIT_MET   1     1        Removed (By similarity). 
CHAIN   2   363  362     Glyceraldehyde-3-phosphate dehydrogenase, muscle. PRO_0000145487
NP_BIND   11    12  2     NAD (By similarity). 
REGION   179   181  3     Glyceraldehyde 3-phosphate binding (By similarity). 
REGION   239   240  2     Glyceraldehyde 3-phosphate binding (By similarity). 
ACT_SITE   180   180        Nucleophile (By similarity). 
BINDING   63    63        NAD (By similarity). 
BINDING   108   108        NAD; via carbonyl oxygen (By similarity). 
BINDING   210   210        Glyceraldehyde 3-phosphate (By similarity). 
BINDING   262   262        Glyceraldehyde 3-phosphate (By similarity). 
BINDING   344   344        NAD (By similarity). 
SITE   207   207  1     Activates thiol group during catalysis (By similarity). 
MOD_RES   180   180        ADP-ribosylcysteine; by autocatalysis; in irreversibly inhibited form (By similarity). 
MOD_RES   180   180        S-nitrosocysteine; in reversibly inhibited form (By similarity). 
Sequence information
Length: 363 AA [This is the length of the unprocessed precursor] Molecular weight: 39413 Da [This is the MW of the unprocessed precursor] CRC64: 6CB549D9A1163C3F [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MVKVGVNGFG RIGRLVTRAA FNSGKVDIVA INDPFIDLNY MVYMFKYDST HGKFKVDIVA 

        70         80         90        100        110        120 
INDPFIDLNY MVYMFKYDST HGKFKGTVKA ENGKLVINGH AITIFQERDP SKIKWGDAGA 

       130        140        150        160        170        180 
EYVVESTGVF TTMEKAGAHL KGGAKRVIIS APSRDAPMFV MGVNHEKYDK SLKIVSNASC 

       190        200        210        220        230        240 
TTNCLAPLAK VIHDNFGIVE GLMTTVHAIT ATQKTVDGPS AKLWRDGAGA AQNIIPASTG 

       250        260        270        280        290        300 
AAKAVGKVIP ELNGKLTGMA FRVPTANVSV VDLTCRLEKP AKYDDIKRVV KQACDGPLKG 

       310        320        330        340        350        360 
MLGYTEHQVV SSDFNGDSHS STFDAGAGIA LNDHFVKLVS WYDNEFGYSN RVVDLMVHMA 


SKE
P80534 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

BLAST logo BLAST submission on ExPASy/SIB
or at NCBI (USA) 		Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Hosted by kr flag YPRC Korea Mirror sites: Australia Brazil Canada China Switzerland
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!