[1]	PROTEIN SEQUENCE. PubMed=8504802 [NCBI, ExPASy, EBI, Israel, Japan] Rueetschi U., Nordin I., Odelhoeg B., Joernvall H., Lindstedt S.; "Gamma-butyrobetaine hydroxylase. Structural characterization of the Pseudomonas enzyme."; Eur. J. Biochem. 213:1075-1080(1993).

Comments

FUNCTION: Catalyzes the formation of L-carnitine from gamma-butyrobetaine.
CATALYTIC ACTIVITY: 4-trimethylammoniobutanoate + 2-oxoglutarate + O₂ = 3-hydroxy-4-trimethylammoniobutanoate + succinate + CO₂.
COFACTOR: Iron.
COFACTOR: Ascorbate.
PATHWAY: Amine and polyamine biosynthesis; carnitine biosynthesis .
SUBUNIT: Homodimer.
SUBCELLULAR LOCATION: Cytoplasm.
SIMILARITY: Belongs to the gamma-BBH/TMLD family.

Copyright

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Cross-references

3D structure databases
ModBase	P80193.
Enzyme and pathway databases
BioCyc	MetaCyc:MON-8461; -.
Family and domain databases
InterPro	IPR012775; 2-oxoglut_dOase. IPR003819; Taurine_dOase. Graphical view of domain structure.
Pfam	PF02668; TauD; 1. Pfam graphical view of domain structure.
TIGRFAMs	TIGR02409; carnitine_bodg; 1.
BLOCKS	P80193.
Other
ProtoNet	P80193.
UniRef	View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Carnitine biosynthesis; Cytoplasm; Dioxygenase; Direct protein sequencing; Iron; Oxidoreductase.

Features

Feature table viewer

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 383`	`383`	`Gamma-butyrobetaine dioxygenase.`	`PRO_0000207089`
`VARIANT`	`1 1`	`1`	`Missing (in 50% of the chains).`

Sequence information

Length: 383 AA [This is the length of the unprocessed precursor]

Molecular weight: 43322 Da [This is the MW of the unprocessed precursor]

CRC64: 1A16205902C92DB9 [This is a checksum on the sequence]

        10         20         30         40         50         60 
NAIADYRTFP LISPLASAAS FASGVSVTWA DGRVSPFHNL WLRDNCPCGD CVYEVTREQV 

        70         80         90        100        110        120 
FLVADVPEDI QVQAVTIGDD GRLVVQWDDG HASAYHPGWL RAHAYDAQSL AEREAARPHK 

       130        140        150        160        170        180 
HRWMQGLSLP VYDHGAVMQD DDTLLEWLLA VRDVGLTQLH GVPTEPGALI PLAKRISFIR 

       190        200        210        220        230        240 
ESNFGVLFDV RSKADADSNA YTAFNLPLHT DLPTRELQPG LQFLHCLVND ATGGNSTFVD 

       250        260        270        280        290        300 
GFAIAEALRI EAPAAYRLLC ETPVEFRNKD RHSDYRCTAP VIALDSSGEV REIRLANFLR 

       310        320        330        340        350        360 
APFQMDAQRM PDYYLAYRRF IQMTREPRFC FTRRLEAGQL WCFDNRRVLH ARDAFDPASG 

       370        380 
DRHFQGCYVD RDELLSRILV LQR

P80193 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
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	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools