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UniProtKB/Swiss-Prot entry P78574


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name CATA_ASPFU
Primary accession number P78574
Secondary accession number Q4WD88
Integrated into Swiss-Prot on November 1, 1997
Sequence was last modified on December 6, 2005 (Sequence version 2)
Annotations were last modified on    July 22, 2008 (Entry version 50)
Name and origin of the protein
Protein name Catalase A
Synonyms EC 1.11.1.6
Fast catalase
Gene name
Name: catA
ORFNames: AFUA_6G03890
From
Aspergillus fumigatus (Sartorya fumigata) [TaxID: 5085] 
Taxonomy Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; Eurotiomycetidae; Eurotiales; Trichocomaceae; mitosporic Trichocomaceae; Aspergillus.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Wysong D.R., Diamond R.D., Robbins P.W.;
"Cloning, sequencing and characterization of Aspergillus fumigatus catalase genes.";
Submitted (FEB-1997) to the EMBL/GenBank/DDBJ databases.
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Af293 / CBS 101355 / FGSC A1100;
DOI=10.1038/nature04332; PubMed=16372009 [NCBI, ExPASy, EBI, Israel, Japan]
Nierman W.C., Pain A., Anderson M.J., Wortman J.R., Kim H.S., Arroyo J., Berriman M., Abe K., Archer D.B., Bermejo C., Bennett J.W., Bowyer P., Chen D., Collins M., Coulsen R., Davies R., Dyer P.S., Farman M.L., Fedorova N., Fedorova N.D., Feldblyum T.V., Fischer R., Fosker N., Fraser A., Garcia J.L., Garcia M.J., Goble A., Goldman G.H., Gomi K., Griffith-Jones S., Gwilliam R., Haas B.J., Haas H., Harris D.E., Horiuchi H., Huang J., Humphray S., Jimenez J., Keller N., Khouri H., Kitamoto K., Kobayashi T., Konzack S., Kulkarni R., Kumagai T., Lafton A., Latge J.-P., Li W., Lord A., Lu C., Majoros W.H., May G.S., Miller B.L., Mohamoud Y., Molina M., Monod M., Mouyna I., Mulligan S., Murphy L.D., O'Neil S., Paulsen I., Penalva M.A., Pertea M., Price C., Pritchard B.L., Quail M.A., Rabbinowitsch E., Rawlins N., Rajandream M.A., Reichard U., Renauld H., Robson G.D., Rodriguez de Cordoba S., Rodriguez-Pena J.M., Ronning C.M., Rutter S., Salzberg S.L., Sanchez M., Sanchez-Ferrero J.C., Saunders D., Seeger K., Squares R., Squares S., Takeuchi M., Tekaia F., Turner G., Vazquez de Aldana C.R., Weidman J., White O., Woodward J.R., Yu J.-H., Fraser C.M., Galagan J.E., Asai K., Machida M., Hall N., Barrell B.G., Denning D.W.;
"Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus.";
Nature 438:1151-1156(2005).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
U87630; AAB47761.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AAHF01000012; EAL85650.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq XP_747688.1; -.
3D structure databases
HSSP P21179; 1CF9. [HSSP ENTRY / PDB]
ModBase P78574.
Protein family/group databases
PeroxiBase 5205; AfumKat01.
Family and domain databases
InterPro IPR002226; Catalase.
IPR010582; Catalase-rel.
IPR011614; Catalase_N.
Graphical view of domain structure.
Gene3D G3DSA:2.40.180.10; Catalase_N; 1.
PANTHER PTHR11465; Catalase; 1.
Pfam PF00199; Catalase; 1.
PF06628; Catalase-rel; 1.
Pfam graphical view of domain structure.
PRINTS PR00067; CATALASE.
ProDom PD000510; Catalase; 1.
[Domain structure / List of seq. sharing at least 1 domain]
PROSITE PS00437; CATALASE_1; 1.
PS00438; CATALASE_2; 1.
BLOCKS P78574.
Genome annotation databases
GeneID 3505035; -.
KEGG afm:AFUA_6G03890; -.
Phylogenomic databases
HOGENOM P78574; -.
Other
ProtoNet P78574.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Heme; Hydrogen peroxide; Iron; Metal-binding; Oxidoreductase; Peroxidase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   750  750     Catalase A. PRO_0000084915
ACT_SITE   93    93        By similarity. 
ACT_SITE   166   166        By similarity. 
METAL   380   380        Iron (heme axial ligand) (By similarity). 
CONFLICT   328   328        D -> N (in Ref. 1; AAB47761). 
CONFLICT   462   462        S -> N (in Ref. 1; AAB47761). 
CONFLICT   577   577        F -> S (in Ref. 1; AAB47761). 
CONFLICT   604   605        DG -> T (in Ref. 1; AAB47761). 
CONFLICT   681   681        D -> H (in Ref. 1; AAB47761). 
Sequence information
Length: 750 AA [This is the length of the unprocessed precursor] Molecular weight: 84633 Da [This is the MW of the unprocessed precursor] CRC64: 95AA8090D28BA007 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MATKIAGGLH RAQEVLQNTS SKSKKLVDLE RDTADAHTQQ PLTTDHGVRV SNTDQWLRVT 

        70         80         90        100        110        120 
NDRRTGPSLL EDQIAREKIH RFDHERIPER VVHARGTGAF GNFKLKESIE DLTYAGVLTD 

       130        140        150        160        170        180 
TSRNTPVFVR FSTVQGSRGS ADTVRDVRGF AVKFYTDEGN WDIVGNNIPV FFIQDAVKFP 

       190        200        210        220        230        240 
DFVHAVKPEP HNEVPQAQTA HNNFWDFVYL HPEATHMFMW AMSDRAIPRS YRMMQGFGVN 

       250        260        270        280        290        300 
TFALVNKEGK RHFVKFHWIP HLGVHSLVWD EALKLGGQDP DFHRKDLMEA IDNKAYPKWD 

       310        320        330        340        350        360 
FAIQVIPEEK QDDFEFDILD ATKIWPEDLV PLRVIGELEL NRNVDEFFPQ TEQVAFCTSH 

       370        380        390        400        410        420 
IVPGIDFTDD PLLQGRNFSY FDTQISRLGI NWEELPINRP VCPVLNHNRD GQMRHRITQG 

       430        440        450        460        470        480 
TVNYWPNRFE AVPPTGTKGS GVGGGFTTYP QRVEGIKNRA LSDKFREHHN QAQLFYNSMS 

       490        500        510        520        530        540 
EHEKLHMKKA FSFELDHCDD PTVYERLAGH RLAEIDLELA QKVAEMVGAP IPAKALKQNH 

       550        560        570        580        590        600 
GRRAPHLSQT EFIPKNPTIA SRRIAIIIGD GYDPVAFTGL KTAIKAASAL PFIIGTKRSA 

       610        620        630        640        650        660 
IYADGEDKTS SKGIIPDHHY DGQRSTMFDA TFIPGGPHVA TLRQNGQIKY WISETFGHLK 

       670        680        690        700        710        720 
ALGATGEAVD LVKETLSGTL DVQVASSQSP EPVEWYGVVT AGGKQKPESF KESVQILKGA 

       730        740        750 
TDFVGKFFYQ ISQHRNYQRE LDGLASTIAF 

P78574 in FASTA format

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