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UniProtKB/Swiss-Prot entry P65879

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name PURA_BRUSU
Primary accession number P65879
Secondary accession numbers Q8FZ20 Q8YIU1
Integrated into Swiss-Prot on October 11, 2004
Sequence was last modified on October 11, 2004 (Sequence version 1)
Annotations were last modified on    September 2, 2008 (Entry version 31)
Name and origin of the protein
Protein name Adenylosuccinate synthetase
Synonyms EC 6.3.4.4
IMP--aspartate ligase
AdSS
AMPSase
Gene name
Name: purA
OrderedLocusNames: BR1683
From
Brucella suis [TaxID: 29461] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales; Brucellaceae; Brucella.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=1330 / Biovar 1;
DOI=10.1073/pnas.192319099; PubMed=12271122 [NCBI, ExPASy, EBI, Israel, Japan]
Paulsen I.T., Seshadri R., Nelson K.E., Eisen J.A., Heidelberg J.F., Read T.D., Dodson R.J., Umayam L.A., Brinkac L.M., Beanan M.J., Daugherty S.C., DeBoy R.T., Durkin A.S., Kolonay J.F., Madupu R., Nelson W.C., Ayodeji B., Kraul M., Shetty J., Malek J.A., Van Aken S.E., Riedmuller S., Tettelin H., Gill S.R., White O., Salzberg S.L., Hoover D.L., Lindler L.E., Halling S.M., Boyle S.M., Fraser C.M.;
"The Brucella suis genome reveals fundamental similarities between animal and plant pathogens and symbionts.";
Proc. Natl. Acad. Sci. U.S.A. 99:13148-13153(2002).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE014291; AAN30583.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_698668.1; -.
3D structure databases
HSSP P12283; 1ADE. [HSSP ENTRY / PDB]
ModBase P65879.
Enzyme and pathway databases
BioCyc BSUI204722:BR_1683-MON; -.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0004019; Molecular function: adenylosuccinate synthase activity (inferred from electronic annotation from HAMAP).
GO:0005525; Molecular function: GTP binding (inferred from electronic annotation from HAMAP).
GO:0000287; Molecular function: magnesium ion binding (inferred from electronic annotation from HAMAP).
GO:0006164; Biological process: purine nucleotide biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00011; -; 1.
PBIL [Tree]
InterPro IPR001114; AdlSucc_Synth.
Graphical view of domain structure.
PANTHER PTHR11846; Asucc_synthtase; 1.
Pfam PF00709; Adenylsucc_synt; 1.
Pfam graphical view of domain structure.
ProDom PD001188; Asucc_synthtase; 1.
[Domain structure / List of seq. sharing at least 1 domain]
SMART SM00788; Adenylsucc_synt; 1.
SMART graphical view of domain structure.
TIGRFAMs TIGR00184; purA; 1.
PROSITE PS01266; ADENYLOSUCCIN_SYN_1; 1.
PS00513; ADENYLOSUCCIN_SYN_2; 1.
Genome annotation databases
GeneID 1167376; -.
GenomeReviews AE014291_GR; BR1683.
KEGG bms:BR1683; -.
TIGR BR1683; -.
Phylogenomic databases
HOGENOM P65879; -.
Other
ProtoNet P65879.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Cytoplasm; GTP-binding; Ligase; Magnesium; Metal-binding; Nucleotide-binding; Purine biosynthesis.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   429  429     Adenylosuccinate synthetase. PRO_0000095156
NP_BIND   12    18  7     GTP (Potential). 
ACT_SITE   140   140        By similarity. 
ACT_SITE   147   147        By similarity. 
METAL   13    13        Magnesium (By similarity). 
METAL   40    40        Magnesium; via carbonyl oxygen (By similarity). 
Sequence information
Length: 429 AA [This is the length of the unprocessed precursor] Molecular weight: 46561 Da [This is the MW of the unprocessed precursor] CRC64: DF90E83E30690FF2 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MANVVVVGSQ WGDEGKGKIV DWLSERADVI VRYQGGHNAG HTLVIDGVSY KLSLLPSGLV 

        70         80         90        100        110        120 
RGKLSVIGNG VVVDPHHFVA EVEKLRGQGI DVTPDVLRVA ENAPLILSIH RELDAMREGS 

       130        140        150        160        170        180 
NSGLKIGTTK RGIGPAYEDK VGRRAIRVID LTEPETLRPK VERLLAHHNS LRRGMGLEEI 

       190        200        210        220        230        240 
AVETILTELT SVADQILPYI DQVWRVLDER RKAGARILFE GAQGALLDND HGTYPFVTSS 

       250        260        270        280        290        300 
NTVAGQAAAG SGLGPTAIGY VLGITKAYTT RVGEGPFPTE LNDEIGEFLG TKGHEFGVVT 

       310        320        330        340        350        360 
GRKRRCGWFD AVIVRQTVRT SGINGIALTK LDVLDGLEEI KICVAYELDG KRIDYLPSSM 

       370        380        390        400        410        420 
GAQARVKPIY ETLPGWSETT AGARSWNDLP AQAVKYVRHI EELIGAPVAM LSTSPEREDT 


ILVTDPFHD
P65879 in FASTA format

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