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UniProtKB/Swiss-Prot entry P60565


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name GUAC_LACJO
Primary accession number P60565
Secondary accession numbers None
Integrated into Swiss-Prot on March 15, 2004
Sequence was last modified on March 15, 2004 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 35)
Name and origin of the protein
Protein name GMP reductase
Synonyms EC 1.7.1.7
Guanosine 5'-monophosphate oxidoreductase
Guanosine monophosphate reductase
Gene name
Name: guaC
OrderedLocusNames: LJ_0441
From
Lactobacillus johnsonii [TaxID: 33959] [HAMAP proteome]
Taxonomy Bacteria; Firmicutes; Lactobacillales; Lactobacillaceae; Lactobacillus.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=NCC 533;
DOI=10.1073/pnas.0307327101; PubMed=14983040 [NCBI, ExPASy, EBI, Israel, Japan]
Pridmore R.D., Berger B., Desiere F., Vilanova D., Barretto C., Pittet A.-C., Zwahlen M.-C., Rouvet M., Altermann E., Barrangou R., Mollet B., Mercenier A., Klaenhammer T., Arigoni F., Schell M.A.;
"The genome sequence of the probiotic intestinal bacterium Lactobacillus johnsonii NCC 533.";
Proc. Natl. Acad. Sci. U.S.A. 101:2512-2517(2004).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE017198; AAS08432.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_964466.1; -.
3D structure databases
ModBase P60565.
Enzyme and pathway databases
BioCyc LJOH257314:LJ_0441-MON; -.
Ontologies
GO
GO:0003920; Molecular function: GMP reductase activity (inferred from electronic annotation from HAMAP).
GO:0006163; Biological process: purine nucleotide metabolic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_01511; -; 1.
PBIL [Tree]
InterPro IPR013785; Aldolase_TIM.
IPR005994; GMP_reduct2.
IPR015875; IMP_DH/GMP_Rdtase_CS.
IPR001093; IMP_DHase_GMPRtase.
Graphical view of domain structure.
Gene3D G3DSA:3.20.20.70; Aldolase_TIM; 1.
Pfam PF00478; IMPDH; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF036500; GMP_red_Firmic; 1.
TIGRFAMs TIGR01306; GMP_reduct_2; 1.
PROSITE PS00487; IMP_DH_GMP_RED; 1.
BLOCKS P60565.
Genome annotation databases
GeneID 2742024; -.
GenomeReviews AE017198_GR; LJ_0441.
KEGG ljo:LJ0441; -.
NMPDR fig|257314.1.peg.452; -.
Phylogenomic databases
HOGENOM P60565; -.
Genome annotation databases
CMR P60565; LJ_0441.
Other
ProtoNet P60565.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; NADP; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   330  330     GMP reductase. PRO_0000093759
NP_BIND   209   232  24     NADP (By similarity). 
ACT_SITE   180   180        Thioimidate intermediate (By similarity). 
Sequence information
Length: 330 AA [This is the length of the unprocessed precursor] Molecular weight: 36625 Da [This is the MW of the unprocessed precursor] CRC64: 39E5484AB0C831DA [This is a checksum on the sequence]
        10         20         30         40         50         60 
MSNYFSMEAF DYDDIQLVPN KCIIKSRSEA DTGVKFGSRT FKIPVVPANM ESVIDEDLAI 

        70         80         90        100        110        120 
WLAEHGYYYV MHRFYPEKRA DFIKMMHDKG LFASISVGIK DSEYDFIDYL AKENIIPEYT 

       130        140        150        160        170        180 
TIDVAHGHSD YVIKMIKYIK EKLPDTFLTA GNIATPEAVR ELENAGADAT KVGVGPGRAC 

       190        200        210        220        230        240 
ITKLKTGFGT GGWQLAALRM CSKAARKPLI ADGGIRHNGD IAKSVRFGAS MVMIGSLFAG 

       250        260        270        280        290        300 
HEESPGNLIT IDGKRYKQYW GSASEVQKGA YRNVEGKQML VPYRGSIKDT LREMQEDLQS 

       310        320        330 
SISYAGGKDL SAIRVVDYVI VKSSIFDGDK 

P60565 in FASTA format

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BLAST logo BLAST submission on ExPASy/SIB
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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
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