ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!
Search for

UniProtKB/Swiss-Prot entry P59390

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

Note: most headings are clickable, even if they don't appear as links. They link to the user manual or other documents.
Entry information
Entry name LDH2_LACPL
Primary accession number P59390
Secondary accession numbers None
Integrated into Swiss-Prot on March 25, 2003
Sequence was last modified on March 25, 2003 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 41)
Name and origin of the protein
Protein name L-lactate dehydrogenase 2
Synonyms L-LDH 2
EC 1.1.1.27
Gene name
Name: ldh2
Synonyms: ldhL2
OrderedLocusNames: lp_1101
From
Lactobacillus plantarum [TaxID: 1590] [HAMAP proteome]
Taxonomy Bacteria; Firmicutes; Lactobacillales; Lactobacillaceae; Lactobacillus.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC BAA-793 / NCIMB 8826 / WCFS1;
DOI=10.1073/pnas.0337704100; PubMed=12566566 [NCBI, ExPASy, EBI, Israel, Japan]
Kleerebezem M., Boekhorst J., van Kranenburg R., Molenaar D., Kuipers O.P., Leer R., Tarchini R., Peters S.A., Sandbrink H.M., Fiers M.W.E.J., Stiekema W., Klein Lankhorst R.M., Bron P.A., Hoffer S.M., Nierop Groot M.N., Kerkhoven R., De Vries M., Ursing B., De Vos W.M., Siezen R.J.;
"Complete genome sequence of Lactobacillus plantarum WCFS1.";
Proc. Natl. Acad. Sci. U.S.A. 100:1990-1995(2003).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AL935255; CAD63629.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_784782.1; -.
3D structure databases
HSSP P00344; 2LDB. [HSSP ENTRY / PDB]
ModBase P59390.
Enzyme and pathway databases
BioCyc LPLA220668:LP_1101-MON; -.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0004459; Molecular function: L-lactate dehydrogenase activity (inferred from electronic annotation from HAMAP).
GO:0019642; Biological process: anaerobic glycolysis (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00488; -; 1.
PBIL [Tree]
InterPro IPR001557; L-lactate/malate_DHase.
IPR011304; L-lactate_DHase.
IPR001236; Lactate/malate_DHase.
IPR015955; Lactate_DHase/Glyco_Ohase_4_C.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.
Gene3D G3DSA:3.90.110.10; lact_mal_DH; 1.
G3DSA:3.40.50.720; NAD(P)-bd; 1.
Pfam PF02866; Ldh_1_C; 1.
PF00056; Ldh_1_N; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000102; Lac_mal_DH; 1.
PRINTS PR00086; LLDHDRGNASE.
TIGRFAMs TIGR01771; L-LDH-NAD; 1.
PROSITE PS00064; L_LDH; 1.
BLOCKS P59390.
Genome annotation databases
GeneID 1063343; -.
GenomeReviews AL935263_GR; lp_1101.
KEGG lpl:lp_1101; -.
NMPDR fig|220668.1.peg.916; -.
Phylogenomic databases
HOGENOM P59390; -.
Genome annotation databases
CMR P59390; lp_1101.
Other
ProtoNet P59390.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Cytoplasm; Glycolysis; NAD; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   309  309     L-lactate dehydrogenase 2. PRO_0000168358
NP_BIND   14    42  29     NAD (By similarity). 
ACT_SITE   177   177        Proton acceptor (By similarity). 
BINDING   90    90        Substrate (By similarity). 
BINDING   122   122        NAD or substrate (By similarity). 
BINDING   153   153        Substrate (By similarity). 
BINDING   227   227        Substrate (By similarity). 
Sequence information
Length: 309 AA [This is the length of the unprocessed precursor] Molecular weight: 33116 Da [This is the MW of the unprocessed precursor] CRC64: A0DF444AC833060D [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MDKKQRKVVI VGDGSVGSSF AFSLVQNCAL DELVIVDLVK THAEGDVKDL EDVAAFTNAT 

        70         80         90        100        110        120 
NIHTGEYADA RDADIVVITA GVPRKPGESR LDLINRNTKI LESIVKPVVA SGFNGCFVIS 

       130        140        150        160        170        180 
SNPVDILTSM TQRLSGFPRH RVIGTGTSLD TARLRVALAQ KLNVATTAVD AAVLGEHGDS 

       190        200        210        220        230        240 
SIVNFDEIMI NAQPLKTVTT VDDQFKAEIE QAVRGKGGQI ISQKGATFYG VAVSLMQICR 

       250        260        270        280        290        300 
AILNDENAEL IVSAALSGQY GINDLYLGSP AIINRNGLQK VIEAELSDDE RARMQHFAAK 


MLTMMNVAS
P59390 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

BLAST logo BLAST submission on ExPASy/SIB
or at NCBI (USA) 		Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Hosted by kr flag YPRC Korea Mirror sites: Australia Brazil Canada China Switzerland
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!