ID   PHGR_EUBOX              Reviewed;          13 AA.
AC   P57793;
DT   27-APR-2001, integrated into UniProtKB/Swiss-Prot.
DT   27-APR-2001, sequence version 1.
DT   04-NOV-2008, entry version 23.
DE   RecName: Full=Phloroglucinol reductase;
DE            EC=1.3.1.57;
DE   Flags: Fragment;
OS   Eubacterium oxidoreducens.
OC   Bacteria; Firmicutes; Clostridia; Clostridiales; Eubacteriaceae;
OC   Eubacterium.
OX   NCBI_TaxID=1732;
RN   [1]
RP   PROTEIN SEQUENCE, AND CHARACTERIZATION.
RC   STRAIN=G-41;
RX   MEDLINE=89174692; PubMed=2925649;
RA   Haddock J.D., Ferry J.G.;
RT   "Purification and properties of phloroglucinol reductase from
RT   Eubacterium oxidoreducens G-41.";
RL   J. Biol. Chem. 264:4423-4427(1989).
CC   -!- FUNCTION: Functions in the pathway of anaerobic degradation of
CC       trihydroxybenzenes by catalyzing reduction of the aromatic nucleus
CC       prior to ring fission.
CC   -!- CATALYTIC ACTIVITY: Dihydrophloroglucinol + NADP(+) =
CC       phloroglucinol + NADPH.
CC   -!- BIOPHYSICOCHEMICAL PROPERTIES:
CC       pH dependence:
CC         Optimum pH is 7.8 for the forward reaction;
CC       Temperature dependence:
CC         Optimum temperature is 40 degrees Celsius for the forward
CC         reaction;
CC   -!- SUBUNIT: Homodimer.
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DR   PIR; A32453; A32453.
DR   GO; GO:0018510; F:phloroglucinol reductase activity; IEA:EC.
DR   GO; GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Aromatic hydrocarbons catabolism; Direct protein sequencing; NADP;
KW   Oxidoreductase.
FT   CHAIN         1    >13       Phloroglucinol reductase.
FT                                /FTId=PRO_0000058379.
FT   NON_TER      13     13
SQ   SEQUENCE   13 AA;  1530 MW;  427E2E0833F1CB13 CRC64;
     XVPCNKEFVX NXF
//