ID   MALF2_MALFU             Reviewed;         177 AA.
AC   P56577;
DT   15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT   15-DEC-1998, sequence version 1.
DT   25-NOV-2008, entry version 42.
DE   RecName: Full=Putative peroxiredoxin;
DE            EC=1.11.1.15;
DE   AltName: Full=Thioredoxin reductase;
DE   AltName: Full=MF1;
DE   AltName: Allergen=Mal f 2;
OS   Malassezia furfur (Pityriasis versicolor infection agent)
OS   (Pityrosporum orbiculare).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC   Ustilaginomycotina incertae sedis; Malasseziales; Malassezia.
OX   NCBI_TaxID=55194;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=TIMM 2782;
RX   MEDLINE=98342073; PubMed=9675120; DOI=10.1006/bbrc.1998.8944;
RA   Yasueda H., Hashida-Okado T., Saito A., Uchida K., Kuroda M.,
RA   Onishi Y., Takahashi K., Yamaguchi H., Takesako K., Akiyama K.;
RT   "Identification and cloning of two novel allergens from the lipophilic
RT   yeast, Malassezia furfur.";
RL   Biochem. Biophys. Res. Commun. 248:240-244(1998).
CC   -!- CATALYTIC ACTIVITY: 2 R'-SH + ROOH = R'-S-S-R' + H(2)O + ROH.
CC   -!- SUBCELLULAR LOCATION: Peroxisome (Potential).
CC   -!- ALLERGEN: Causes an allergic reaction in human.
CC   -!- SIMILARITY: Belongs to the peroxiredoxin 2 family.
CC   -!- SIMILARITY: Contains 1 thioredoxin domain.
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DR   EMBL; AB011804; BAA32435.1; -; Genomic_DNA.
DR   PIR; JE0226; JE0226.
DR   GO; GO:0005777; C:peroxisome; IEA:UniProtKB-KW.
DR   GO; GO:0051920; F:peroxiredoxin activity; IEA:EC.
DR   GO; GO:0045454; P:cell redox homeostasis; IEA:InterPro.
DR   GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW.
DR   InterPro; IPR013740; Redoxin.
DR   InterPro; IPR012335; Thioredoxin_fold.
DR   Gene3D; G3DSA:3.40.30.10; Thioredoxin_fold; 1.
DR   Pfam; PF08534; Redoxin; 1.
DR   PROSITE; PS51352; THIOREDOXIN_2; 1.
PE   1: Evidence at protein level;
KW   Allergen; Oxidoreductase; Peroxidase; Peroxisome; Redox-active center.
FT   CHAIN         1    177       Putative peroxiredoxin.
FT                                /FTId=PRO_0000056606.
FT   DOMAIN        8    177       Thioredoxin.
FT   MOTIF       175    177       Microbody targeting signal (By
FT                                similarity).
SQ   SEQUENCE   177 AA;  19193 MW;  1E1F907C68E51031 CRC64;
     MPGDPTATAK GNEIPDTLMG YIPWTPELDS GEVCGIPTTF KTRDEWKGKK VVIVSIPGAY
     TPICHQQHIP PLVKRVDELK AKGVDAVYVI ASNDPFVMAA WGNFNNAKDK VVFATDIDLA
     FSKALGATID LSAKHFGERT ARYALIIDDN KIVDFASDEG DTGKLQNASI DTILTKV
//