[1]	NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. DOI=10.1038/387394a0; PubMed=9163424 [NCBI, ExPASy, EBI, Israel, Japan] Freiberg C.A., Fellay R., Bairoch A., Broughton W.J., Rosenthal A., Perret X.; "Molecular basis of symbiosis between Rhizobium and legumes."; Nature 387:394-401(1997).

Comments

CATALYTIC ACTIVITY: Succinate semialdehyde + NAD(P)⁺ + H₂O = succinate + NAD(P)H.
PATHWAY: Amino-acid degradation; 4-aminobutanoate degradation .
SIMILARITY: Belongs to the aldehyde dehydrogenase family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

U00090; AAB91849.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

PIR

S43963; S43963.

RefSeq

NP_444062.1; -.

3D structure databases

HSSP

P05091; 1O01. [HSSP ENTRY / PDB]

ModBase

P55653.

Family and domain databases

InterPro

IPR016160; Ald_DHase_CS.
IPR016162; Ald_DHase_N.
IPR015590; Aldehyde_DHase.
IPR010102; Succ_semiAld_DHase.
Graphical view of domain structure.

Gene3D

G3DSA:3.40.605.10; Aldehyde_dehydrogenase_N; 1.

PANTHER

PTHR11699; Aldehyde_dehyd; 1.

Pfam

PF00171; Aldedh; 1.
Pfam graphical view of domain structure.

TIGRFAMs

TIGR01780; SSADH; 1.

PROSITE

PS00070; ALDEHYDE_DEHYDR_CYS; FALSE_NEG.
PS00687; ALDEHYDE_DEHYDR_GLU; 1.

BLOCKS

P55653.

Genome annotation databases

GeneID

962447; -.

Other

ProtoNet

P55653.

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

NADP; Oxidoreductase; Plasmid.

Features

Feature table viewer

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 491`	`491`	`Probable succinate-semialdehyde dehydrogenase [NADP+].`	`PRO_0000056573`
`NP_BIND`	`241 246`	`6`	`NADP (By similarity).`
`ACT_SITE`	`263 263`		`By similarity.`
`ACT_SITE`	`297 297`		`By similarity.`

Sequence information

Length: 491 AA [This is the length of the unprocessed precursor]

Molecular weight: 53254 Da [This is the MW of the unprocessed precursor]

CRC64: FC54C5DF7B4D1B14 [This is a checksum on the sequence]

        10         20         30         40         50         60 
MTLTSALTRH LKCPELFRNL ANEPHPSVAG QRQRFSVFNP STGELLAEVP DMGAADAHAA 

        70         80         90        100        110        120 
IERADAAQEP WSGLTARARS DILWKWHRFI LEHSDDLAAI LTAEMGKPLG EAKSEVQHAA 

       130        140        150        160        170        180 
AYLQWYAEEA NRIYGETISA PSTDRRMLVI KQPIGVVGAI TPWNFPASMV ARKISPALAA 

       190        200        210        220        230        240 
GCTVVLKPAE QTPLVAGAMF ALAKLAGFPD GVLNLVYASE GDAIGRELCT NPKVRKISFT 

       250        260        270        280        290        300 
GSTEVGRLLM RQCSDQIKRI SFELGGNAPF IVFDDADIDA AVDGAIQAKF RNAGQTCVSA 

       310        320        330        340        350        360 
NRIYVQSGVY AEFAEKFTER VRTLKVGDGF DPNVAIGPLI NQEALKKIEL HISDAVQKGA 

       370        380        390        400        410        420 
RVRSGGRRTG SSGTFFEPTV VTDVSKTMRL AEEETFGPLA PLLRFDDADH VVREANDTIY 

       430        440        450        460        470        480 
GLAAYFYASN LKRVWRVAEA LEYGMVGINT GRMSSEAAPF GGVKQSGIGR EGSRHGLEDY 

       490 
LDMKYLCVGG L

P55653 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools