NUCLEOTIDE SEQUENCE [MRNA].
STRAIN=cv. Morex;
DOI=10.1007/BF00014973; PubMed=8555444 [NCBI, ExPASy, EBI, Israel, Japan]
Skadsen R.W., Schulze-Lefert P., Herbst J.M.;
"Molecular cloning, characterization and expression analysis of two catalase isozyme genes in barley.";
Plant Mol. Biol. 29:1005-1014(1995).

Comments

FUNCTION: Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
CATALYTIC ACTIVITY: 2 H₂O₂ = O₂ + 2 H₂O.
COFACTOR: Heme group (By similarity).
SUBUNIT: Homotetramer (By similarity).
SUBCELLULAR LOCATION: Peroxisome (By similarity). Glyoxysome (By similarity).
TISSUE SPECIFICITY: In whole endosperms (aleurones plus starchy endosperm), in isolated aleurones and in developing seeds.
SIMILARITY: Belongs to the catalase family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

U20777; AAA96947.1; -; mRNA.	[EMBL / GenBank / DDBJ] [CoDingSequence]
U16132; AAA62306.1; -; mRNA.	[EMBL / GenBank / DDBJ] [CoDingSequence]

PIR

S62696; S62696.

3D structure databases

HSSP

P46206; 1M7S. [HSSP ENTRY / PDB]

ModBase

P55307.

Organism-specific databases

Gramene

P55307; -.

Family and domain databases

InterPro

IPR002226; Catalase.
IPR011614; Catalase_N.
Graphical view of domain structure.

Gene3D

G3DSA:2.40.180.10; Catalase_N; 1.

PANTHER

PTHR11465; Catalase; 1.

Pfam

PF00199; Catalase; 1.
Pfam graphical view of domain structure.

PRINTS

PR00067; CATALASE.

ProDom

PD000510; Catalase; 1.
[Domain structure / List of seq. sharing at least 1 domain]

PROSITE

PS00437; CATALASE_1; 1.
PS00438; CATALASE_2; 1.

Other

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Glyoxysome; Heme; Hydrogen peroxide; Iron; Metal-binding; Oxidoreductase; Peroxidase; Peroxisome.

Features

Feature table viewer

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 492`	`492`	`Catalase isozyme 1.`	`PRO_0000084941`
`ACT_SITE`	`65 65`		`By similarity.`
`ACT_SITE`	`138 138`		`By similarity.`
`METAL`	`348 348`		`Iron (heme axial ligand) (By similarity).`

Sequence information

Length: 492 AA [This is the length of the unprocessed precursor]

Molecular weight: 56586 Da [This is the MW of the unprocessed precursor]

CRC64: 5917F285FD75D725 [This is a checksum on the sequence]

        10         20         30         40         50         60 
MDPYKHRPTS GANSAYWTTN SGAPVWNNNN ALTVGHRGPI LLEDYHLIEK LAQFDRERIP 

        70         80         90        100        110        120 
ERVVHARGAS AKGFFEVTHD VSQLTCADFL RAPGVQTPVI VRFSTVVHER GSPETLRDPR 

       130        140        150        160        170        180 
GFAVKFYTRE GNFDLVGNNM PVFFIRDGMK FPDMVHAFKP SPKTNMQENW RVVDFFSHHP 

       190        200        210        220        230        240 
ESLHMFTFLF DDVGIPLNYR HMDGFGVNTY TLISRDGKAH LVKFHWKPTC GVKCLLDDEA 

       250        260        270        280        290        300 
VTVGGTCHTH ATKDLTDSIA AGNYPEWKLF IQTIDADHED RFDFDPLDVT KTWPEDIIPL 

       310        320        330        340        350        360 
QPVGRMVLNK NIDNFFAENE QLAFCPAVTV PGIHYSDDKL LQTRIFSYAD TQRHRLGPNY 

       370        380        390        400        410        420 
LMLPVNAPKC AHHNNHHDGL MNFIHRDEEV NYFPSRFDPT RHAEKYPMPP RVLSGCREKC 

       430        440        450        460        470        480 
IIDKENNFKQ AGERYRSFDP ARQDRFLQRW VDALTDARVT HEIQSIWVSY WSQCDASLGQ 

       490 
KLASRLKIKP NM

P55307 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools