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UniProtKB/Swiss-Prot entry P54904


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name P5CR1_ARATH
Primary accession number P54904
Secondary accession numbers None
Integrated into Swiss-Prot on October 1, 1996
Sequence was last modified on October 1, 1996 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 66)
Name and origin of the protein
Protein name Pyrroline-5-carboxylate reductase
Synonyms P5C reductase
P5CR
EC 1.5.1.2
Protein EMBRYO DEFECTIVE 2772
Gene name
Name: PROC1
Synonyms: EMB2772
OrderedLocusNames: At5g14800
ORFNames: T9L3_100
From
Arabidopsis thaliana (Mouse-ear cress) [TaxID: 3702] 
Taxonomy Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliophyta; eudicotyledons; core eudicotyledons; rosids; eurosids II; Brassicales; Brassicaceae; Arabidopsis.
Protein existence 2: Evidence at transcript level;
References
[1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
DOI=10.1104/pp.103.3.771; PubMed=8022935 [NCBI, ExPASy, EBI, Israel, Japan]
Verbruggen N., Villarroel R., van Montagu M.;
"Osmoregulation of a pyrroline-5-carboxylate reductase gene in Arabidopsis thaliana.";
Plant Physiol. 103:771-781(1993).
[2]
NUCLEOTIDE SEQUENCE.
STRAIN=cv. Landsberg erecta;
Verbruggen N., Villarroel R., Hua X., van Montagu M.;
Submitted (OCT-1996) to the EMBL/GenBank/DDBJ databases.
[3]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=cv. Columbia;
DOI=10.1038/35048507; PubMed=11130714 [NCBI, ExPASy, EBI, Israel, Japan]
Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E., Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K., Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L., O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D., Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M., Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L., Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B., Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P., Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M., Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D., Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A., Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I., Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T., Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A., McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U., Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W., Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M., Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S., Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G., Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W., Bevan M., Fransz P.F.;
"Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana.";
Nature 408:823-826(2000).
[4]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
STRAIN=cv. Columbia;
DOI=10.1126/science.1088305; PubMed=14593172 [NCBI, ExPASy, EBI, Israel, Japan]
Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.;
"Empirical analysis of transcriptional activity in the Arabidopsis genome.";
Science 302:842-846(2003).
[5]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B., Feldmann K.A.;
"Full-length cDNA from Arabidopsis thaliana.";
Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
M76538; AAA61346.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
Y08951; CAA70148.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AL391149; CAC01879.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AF410303; AAK95289.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AY097368; AAM19884.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AY087530; AAM65072.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR JQ2334; JQ2334.
RefSeq NP_196984.1; -.
UniGene At.385
3D structure databases
ModBase P54904.
Organism-specific databases
TAIR At5g14800; -.
Gene expression databases
ArrayExpress P54904; -.
GermOnline AT5G14800; Arabidopsis thaliana.
Family and domain databases
InterPro IPR016040; NAD(P)-bd.
IPR004455; NADP_OxRdtase_F420.
IPR000304; P5CR.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
PANTHER PTHR11645; P5CR; 1.
Pfam PF03807; F420_oxidored; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000193; Pyrrol-5-carb_rd; 1.
TIGRFAMs TIGR00112; proC; 1.
PROSITE PS00521; P5CR; 1.
BLOCKS P54904.
Genome annotation databases
GeneID 831332; -.
GenomeReviews BA000015_GR; AT5G14800.
NMPDR fig|3702.1.peg.23618; -.
Other
LinkHub P54904; -.
ProtoNet P54904.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Alternative splicing; Amino-acid biosynthesis; Complete proteome; Cytoplasm; NADP; Oxidoreductase; Proline biosynthesis.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   276  276     Pyrroline-5-carboxylate reductase. PRO_0000187323
Sequence information
Length: 276 AA [This is the length of the unprocessed precursor] Molecular weight: 28624 Da [This is the MW of the unprocessed precursor] CRC64: B577A01C92A3A28B [This is a checksum on the sequence]
        10         20         30         40         50         60 
MEILPIPAES FKVGFIGAGK MAESIARGVV ASGVLPPNRI CTAVHSNLNR RDVFESFGVN 

        70         80         90        100        110        120 
VFSTSEEVVK ESDVVIFSVK PQVVKKAVTE LKSKLSKNKI LVSVAAGIKL NDLQEWSGQD 

       130        140        150        160        170        180 
RFIRVMPNTP AAVGEAASVM SLGTGATEED GAIVAMLFGA VGKILKADEK MFDAVTGLSG 

       190        200        210        220        230        240 
SGPAYIFLAI EALADGGVAA GLPRELALSL ASQTVLGAAT MVSKTGKHPG VLKDDVTSPG 

       250        260        270 
GTTIAGVHEL EKGSFRATLM NAVVAAAKRS RELSQS 

P54904 in FASTA format

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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
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