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UniProtKB/Swiss-Prot entry P53051


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name MALX3_YEAST
Primary accession number P53051
Secondary accession numbers None
Integrated into Swiss-Prot on October 1, 1996
Sequence was last modified on October 1, 1996 (Sequence version 1)
Annotations were last modified on    December 16, 2008 (Entry version 60)
Name and origin of the protein
Protein name Probable alpha-glucosidase FSP2
Synonyms EC 3.2.1.20
Maltase
Flocculent-specific protein 2
Gene name
Name: FSP2
OrderedLocusNames: YGR287C
From
Saccharomyces cerevisiae (Baker's yeast) [TaxID: 4932] 
Taxonomy Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces.
Protein existence 1: Evidence at protein level;
References
[1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Tonouchi A.;
Submitted (AUG-1995) to the EMBL/GenBank/DDBJ databases.
[2]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=ATCC 96604 / S288c / FY1679;
DOI=10.1002/(SICI)1097-0061(19970315)13:3<251::AID-YEA63>3.3.CO;2-I; PubMed=9090054 [NCBI, ExPASy, EBI, Israel, Japan]
Volckaert G., Voet M., Robben J.;
"Sequence analysis of a near-subtelomeric 35.4 kb DNA segment on the right arm of chromosome VII from Saccharomyces cerevisiae carrying the MAL1 locus reveals 15 complete open reading frames, including ZUO1, BGL2 and BIO2 genes and an ABC transporter gene.";
Yeast 13:251-259(1997).
[3]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 96604 / S288c / FY1679;
PubMed=9169869 [NCBI, ExPASy, EBI, Israel, Japan]
Tettelin H., Agostoni-Carbone M.L., Albermann K., Albers M., Arroyo J., Backes U., Barreiros T., Bertani I., Bjourson A.J., Brueckner M., Bruschi C.V., Carignani G., Castagnoli L., Cerdan E., Clemente M.L., Coblenz A., Coglievina M., Coissac E., Defoor E., Del Bino S., Delius H., Delneri D., de Wergifosse P., Dujon B., Durand P., Entian K.-D., Eraso P., Escribano V., Fabiani L., Fartmann B., Feroli F., Feuermann M., Frontali L., Garcia-Gonzalez M., Garcia-Saez M.I., Goffeau A., Guerreiro P., Hani J., Hansen M., Hebling U., Hernandez K., Heumann K., Hilger F., Hofmann B., Indge K.J., James C.M., Klima R., Koetter P., Kramer B., Kramer W., Lauquin G., Leuther H., Louis E.J., Maillier E., Marconi A., Martegani E., Mazon M.J., Mazzoni C., McReynolds A.D.K., Melchioretto P., Mewes H.-W., Minenkova O., Mueller-Auer S., Nawrocki A., Netter P., Neu R., Nombela C., Oliver S.G., Panzeri L., Paoluzi S., Plevani P., Portetelle D., Portillo F., Potier S., Purnelle B., Rieger M., Riles L., Rinaldi T., Robben J., Rodrigues-Pousada C., Rodriguez-Belmonte E., Rodriguez-Torres A.M., Rose M., Ruzzi M., Saliola M., Sanchez-Perez M., Schaefer B., Schaefer M., Scharfe M., Schmidheini T., Schreer A., Skala J., Souciet J.-L., Steensma H.Y., Talla E., Thierry A., Vandenbol M., van der Aart Q.J.M., Van Dyck L., Vanoni M., Verhasselt P., Voet M., Volckaert G., Wambutt R., Watson M.D., Weber N., Wedler E., Wedler H., Wipfli P., Wolf K., Wright L.F., Zaccaria P., Zimmermann M., Zollner A., Kleine K.;
"The nucleotide sequence of Saccharomyces cerevisiae chromosome VII.";
Nature 387:81-84(1997).
[4]
LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
DOI=10.1038/nature02046; PubMed=14562106 [NCBI, ExPASy, EBI, Israel, Japan]
Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S.;
"Global analysis of protein expression in yeast.";
Nature 425:737-741(2003).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
D43761; BAA07818.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
Z73072; CAA97319.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
Z73073; CAA97321.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR S59370; S59370.
RefSeq NP_011803.1; -.
3D structure databases
HSSP P21332; 1UOK. [HSSP ENTRY / PDB]
ModBase P53051.
Protein-protein interaction databases
IntAct P53051; 5.
Organism-specific databases
CYGD YGR287c; -.
SGD S000003519; YGR287C.
Yeast-GFP YGR287C.
Gene expression databases
ArrayExpress P53051; -.
GermOnline YGR287C; Saccharomyces cerevisiae.
Ontologies
GO
GO:0005739; Cellular component: mitochondrion (inferred from direct assay from SGD).
GO:0004558; Molecular function: alpha-glucosidase activity (inferred from electronic annotation from EC).
GO:0043169; Molecular function: cation binding (inferred from electronic annotation from InterPro).
GO:0005515; Molecular function: protein binding (inferred from physical interaction from IntAct).
GO:0000023; Biological process: maltose metabolic process (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
InterPro IPR013780; Glyco_hydro_13_b.
IPR006047; Glyco_hydro_13_cat.
IPR006589; Glyco_hydro_13_sub_cat.
IPR013781; Glyco_hydro_sub_cat.
Graphical view of domain structure.
Gene3D G3DSA:2.60.40.1180; Glyco_hydro_13_b; 1.
G3DSA:3.20.20.80; Glyco_hydro_cat; 1.
Pfam PF00128; Alpha-amylase; 1.
Pfam graphical view of domain structure.
SMART SM00642; Aamy; 1.
SMART graphical view of domain structure.
Genome annotation databases
Ensembl YGR287C; Saccharomyces cerevisiae. [Contig view]
GeneID 853204; -.
GenomeReviews Y13135_GR; YGR287C.
KEGG sce:YGR287C; -.
NMPDR fig|4932.3.peg.2934; -.
Phylogenomic databases
HOGENOM P53051; -.
Other
LinkHub P53051; -.
NextBio 973383; -.
ProtoNet P53051.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Glycosidase; Hydrolase; Maltose metabolism.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   589  589     Probable alpha-glucosidase FSP2. PRO_0000054333
ACT_SITE   215   215        Nucleophile (By similarity). 
ACT_SITE   277   277        Proton donor (By similarity). 
ACT_SITE   352   352        By similarity. 
Sequence information
Length: 589 AA [This is the length of the unprocessed precursor] Molecular weight: 68592 Da [This is the MW of the unprocessed precursor] CRC64: 08869180588053B6 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MTISSAHPET EPKWWKEATF YQIYPASFKD SNDDGWGDMK GIASKLEYIK ELGADAIWIS 

        70         80         90        100        110        120 
PFYDSPQDDM GYDIANYEKV WPTYGTNEDC FALIEKTHKL GMKFITDLVI NHCSSEHEWF 

       130        140        150        160        170        180 
KESRSSKTNP KRDWFFWRPP KGYDAEGKPI PPNNWKSYFG GSAWTFDEKT QEFYLRLFCS 

       190        200        210        220        230        240 
TQPDLNWENE DCRKAIYESA VGYWLDHGVD GFRIDVGSLY SKVVGLPDAP VVDKNSTWQS 

       250        260        270        280        290        300 
SDPYTLNGPR IHEFHQEMNQ FIRNRVKDGR EIMTVGEMQH ASDETKRLYT SASRHELSEL 

       310        320        330        340        350        360 
FNFSHTDVGT SPLFRYNLVP FELKDWKIAL AELFRYINGT DCWSTIYLEN HDQPRSITRF 

       370        380        390        400        410        420 
GDDSPKNRVI SGKLLSVLLS ALTGTLYVYQ GQELGQINFK NWPVEKYEDV EIRNNYNAIK 

       430        440        450        460        470        480 
EEHGENSEEM KKFLEAIALI SRDHARTPMQ WSREEPNAGF SGPSAKPWFY LNDSFREGIN 

       490        500        510        520        530        540 
VEDEIKDPNS VLNFWKEALK FRKAHKDITV YGYDFEFIDL DNKKLFSFTK KYNNKTLFAA 

       550        560        570        580 
LNFSSDATDF KIPNDDSSFK LEFGNYPKKE VDASSRTLKP WEGRIYISE 

P53051 in FASTA format

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View entry in raw text format (no links)
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