ID   DHE3_VITVI              Reviewed;         411 AA.
AC   P52596;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   25-NOV-2008, entry version 41.
DE   RecName: Full=Glutamate dehydrogenase;
DE            Short=GDH;
DE            EC=1.4.1.3;
GN   Name=GDH;
OS   Vitis vinifera (Grape).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliophyta; eudicotyledons; core eudicotyledons;
OC   Vitales; Vitaceae; Vitis.
OX   NCBI_TaxID=29760;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=cv. Sultanina; TISSUE=Shoot;
RX   MEDLINE=96186961; PubMed=8626071; DOI=10.1016/0378-1119(96)83097-6;
RA   Syntichaki K.M., Loulakakis K.A., Roubelakis-Angelakis K.A.;
RT   "The amino-acid sequence similarity of plant glutamate dehydrogenase
RT   to the extremophilic archaeal enzyme conforms to its stress-related
RT   function.";
RL   Gene 168:87-92(1996).
CC   -!- CATALYTIC ACTIVITY: L-glutamate + H(2)O + NAD(P)(+) = 2-
CC       oxoglutarate + NH(3) + NAD(P)H.
CC   -!- SIMILARITY: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
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DR   EMBL; X86924; CAA60507.1; -; mRNA.
DR   PIR; S54797; S54797.
DR   HSSP; P96110; 1B26.
DR   GO; GO:0005488; F:binding; IEA:InterPro.
DR   GO; GO:0004353; F:glutamate dehydrogenase [NAD(P)+] activity; IEA:EC.
DR   GO; GO:0006520; P:amino acid metabolic process; IEA:InterPro.
DR   GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW.
DR   InterPro; IPR006095; Glu/Leu/Phe/Val_DHase.
DR   InterPro; IPR006096; Glu/Leu/Phe/Val_DHase_C.
DR   InterPro; IPR006097; Glu/Leu/Phe/Val_DHase_dimer.
DR   InterPro; IPR014362; Glu_DHase.
DR   InterPro; IPR016040; NAD(P)-bd.
DR   Gene3D; G3DSA:3.40.50.720; NAD(P)-bd; 1.
DR   PANTHER; PTHR11606:SF2; GLFV_DH; 1.
DR   Pfam; PF00208; ELFV_dehydrog; 1.
DR   Pfam; PF02812; ELFV_dehydrog_N; 1.
DR   PIRSF; PIRSF000185; Glu_DH; 1.
DR   PRINTS; PR00082; GLFDHDRGNASE.
DR   PROSITE; PS00074; GLFV_DEHYDROGENASE; 1.
PE   2: Evidence at transcript level;
KW   NAD; Oxidoreductase.
FT   CHAIN         1    411       Glutamate dehydrogenase.
FT                                /FTId=PRO_0000182752.
FT   ACT_SITE    102    102       By similarity.
SQ   SEQUENCE   411 AA;  44546 MW;  A6C8F63237CF06B5 CRC64;
     MNALAATNRN FRHASRILGL DSKLEKSLLI PFREIKVECT IPKDDGSLAT YVGFRVQHDN
     ARGPMKGGIR YHPEVDPDEV NALAQLMTWK TAVVDIPYGG AKGGIGCTPK DLSMSELERL
     TRVFTQKIHD LIGTHTDVPA PDMGTNAQTM AWILDEYSKF HGHSPAVVTG KPIALGGSLG
     REAATGRGVV FATEALLAQH GKSIKGLTFV IQGFGNVGSW VARLIGERGG KIIAVSDVTG
     AVKNQNGLDI VDLLRHKEET GCLTNFSGGD HMDPNELLTH ECDVLIPCAL GGVLNKENAA
     DVKAKFIIEA ANHPTDPEAD EILSKKGGVI LPDIYANAGG VTVSYFEWVQ NIQGFMWEEE
     KVNNELQKYM TKAFHNIKAM CQSHNCSLRM GAFTLAVNRV ACATTLRGWE A
//