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UniProtKB/Swiss-Prot entry P51132


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name UCRI2_TOBAC
Primary accession number P51132
Secondary accession numbers None
Integrated into Swiss-Prot on October 1, 1996
Sequence was last modified on October 1, 1996 (Sequence version 1)
Annotations were last modified on    September 2, 2008 (Entry version 53)
Name and origin of the protein
Protein name Cytochrome b-c1 complex subunit Rieske-2, mitochondrial [Precursor]
Synonyms EC 1.10.2.2
Ubiquinol-cytochrome c reductase iron-sulfur subunit 2
Rieske iron-sulfur protein 2
RISP2
Complex III subunit 5-2
Gene name None
From
Nicotiana tabacum (Common tobacco) [TaxID: 4097] 
Taxonomy Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliophyta; eudicotyledons; core eudicotyledons; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana.
Protein existence 2: Evidence at transcript level;
References
[1]
NUCLEOTIDE SEQUENCE [MRNA].
STRAIN=cv. SC58;
TISSUE=Flower;
DOI=10.1105/tpc.6.3.439; PubMed=8180500 [NCBI, ExPASy, EBI, Israel, Japan]
Huang J., Struck F., Matzinger D.F., Levings C.S. III;
"Flower-enhanced expression of a nuclear-encoded mitochondrial respiratory protein is associated with changes in mitochondrion number.";
Plant Cell 6:439-448(1994).
Comments
  • FUNCTION: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
  • CATALYTIC ACTIVITY: QH2 + 2 ferricytochrome c = Q + 2 ferrocytochrome c + 2 H+.
  • COFACTOR: Binds 1 2Fe-2S cluster per subunit (By similarity).
  • SUBUNIT: The bc1 complex contains 10 subunits; 3 respiratory subunits, 2 core proteins and 5 low-molecular weight proteins.
  • SUBCELLULAR LOCATION: Mitochondrion inner membrane.
  • TISSUE SPECIFICITY: High levels are seen in the flowers while a low level expression is seen in the roots, leaves and stems.
  • MISCELLANEOUS: The Rieske protein is a high potential 2Fe-2S protein.
  • SIMILARITY: Contains 1 Rieske domain.
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
L16810; AAA20831.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR T02027; T02027.
3D structure databases
HSSP P13272; 1RIE. [HSSP ENTRY / PDB]
ModBase P51132.
Family and domain databases
InterPro IPR014349; Rieske.
IPR005805; Rieske_C.
IPR006317; Rieske_proteo.
IPR005806; Rieske_reg.
IPR004192; UCR_TM_region.
Graphical view of domain structure.
Gene3D G3DSA:2.102.10.10; Rieske_reg; 1.
PANTHER PTHR10134; Rieske; 1.
Pfam PF00355; Rieske; 1.
PF02921; UCR_TM; 1.
Pfam graphical view of domain structure.
PRINTS PR00162; RIESKE.
TIGRFAMs TIGR01416; Rieske_proteo; 1.
PROSITE PS51296; RIESKE; 1.
PROSITE graphical view of domain structure (profiles).
BLOCKS P51132.
Other
ProtoNet P51132.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
2Fe-2S; Electron transport; Iron; Iron-sulfur; Membrane; Metal-binding; Mitochondrion; Mitochondrion inner membrane; Oxidoreductase; Respiratory chain; Transit peptide; Transmembrane; Transport.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
TRANSIT   1    60  60     Mitochondrion (Potential). 
CHAIN   61   272  212     Cytochrome b-c1 complex subunit Rieske-2, mitochondrial. PRO_0000030677
DOMAIN   182   270  89     Rieske. 
METAL   215   215        Iron-sulfur (2Fe-2S) (By similarity). 
METAL   217   217        Iron-sulfur (2Fe-2S); via pros nitrogen (By similarity). 
METAL   234   234        Iron-sulfur (2Fe-2S) (By similarity). 
METAL   237   237        Iron-sulfur (2Fe-2S); via pros nitrogen (By similarity). 
DISULFID   220   236        By similarity. 
Sequence information
Length: 272 AA [This is the length of the unprocessed precursor] Molecular weight: 29784 Da [This is the MW of the unprocessed precursor] CRC64: 7D6965C8A0E211AE [This is a checksum on the sequence]
        10         20         30         40         50         60 
MLRIAGRRAS SLSRWPVRSV APSSSAFISA NHFSSDDDSS SPRSISPSLA SVFLHHTRGF 

        70         80         90        100        110        120 
SSNSVSHAHD MGLVPDLPPT VAAIKNPTSK IVYDEHNHER YPPGDPSKRA FAYFVLTGGR 

       130        140        150        160        170        180 
FVYASLVRLL ILKFVLSMSA SKDVLALASL EVDLSSIEPG TTVTVKWRGK PVFIRRRTED 

       190        200        210        220        230        240 
DINLANSVDL GSLRDPQQDA ERVKSPEWLV VIGVCTHLGC IPLPNAGDFG GWFCPCHGSH 

       250        260        270 
YDISGRIRKG PAPYNLEVPT YSFLEENKLL IG 

P51132 in FASTA format

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