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[1]
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NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=Nine Mile;
Schimmels J.A.,
Mallavia L.P.;
Submitted (FEB-1995) to the EMBL/GenBank/DDBJ databases.
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[2]
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NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=Nine Mile phase I;
Thiele D.,
Willems H.,
Oswald W.,
Krauss H.;
Submitted (MAR-1994) to the EMBL/GenBank/DDBJ databases.
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[3]
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NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Nine Mile phase I / RSA 493;
DOI=10.1073/pnas.0931379100; PubMed=12704232 [NCBI, ExPASy, EBI, Israel, Japan]
Seshadri R.,
Paulsen I.T.,
Eisen J.A.,
Read T.D.,
Nelson K.E.,
Nelson W.C.,
Ward N.L.,
Tettelin H.,
Davidsen T.M.,
Beanan M.J.,
DeBoy R.T.,
Daugherty S.C.,
Brinkac L.M.,
Madupu R.,
Dodson R.J.,
Khouri H.M.,
Lee K.H.,
Carty H.A.,
Scanlan D., ![]()
Heinzen R.A.,
Thompson H.A.,
Samuel J.E.,
Fraser C.M.,
Heidelberg J.F.;
"Complete genome sequence of the Q-fever pathogen, Coxiella burnetii.";
Proc. Natl. Acad. Sci. U.S.A. 100:5455-5460(2003).
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[4]
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NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-280.
STRAIN=Nine Mile;
DOI=10.1016/0378-1119(94)00888-Y; PubMed=7698664 [NCBI, ExPASy, EBI, Israel, Japan]
Heinzen R.A.,
Mo Y.-Y.,
Robertson S.J.,
Mallavia L.P.;
"Characterization of the succinate dehydrogenase-encoding gene cluster (sdh) from the rickettsia Coxiella burnetii.";
Gene 155:27-34(1995).
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- FUNCTION: The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3).
- CATALYTIC ACTIVITY: 2-oxoglutarate + [dihydrolipoyllysine-residue succinyltransferase] lipoyllysine = [dihydrolipoyllysine-residue succinyltransferase] S-succinyldihydrolipoyllysine + CO2.
- COFACTOR: Thiamine pyrophosphate.
- SUBUNIT: Homodimer (By similarity).
- SIMILARITY: Belongs to the alpha-ketoglutarate dehydrogenase family.
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Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms.
Distributed under the Creative Commons Attribution-NoDerivs License.
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| Length: 934 AA [This is the length of the unprocessed precursor] |
Molecular weight: 106723 Da [This is the MW of the unprocessed precursor] |
CRC64: 7FB8144F8E013E8D [This is a checksum on the sequence] |
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10 20 30 40 50 60
MPKITMQQFQ KNSYLADNNA GYIETLYENF LKDPHSVNEE WRSYFRTLTN GASTPDISHA
70 80 90 100 110 120
TIREEFRELA RKPRSISPTA ITPAAEQAAV DLLIEGYRRF GHLNAKINPL GDNRPVDSRL
130 140 150 160 170 180
ELGHYNLTES DFNKTFATYG LLNKPKATLK EIYTRLREIY CGSIGVQYST ISDERERNWL
190 200 210 220 230 240
RDYVEQRLPS IEFDKETKRN ILQQLVTAES LEKYLDTKYV GQVRYSLEGG DSLIPLLDEL
250 260 270 280 290 300
TKRARHQKIE EIVICMAHRG RVNVLLNIMG QSAAELFQEF EGKKDYGLMS GDVKYHRGYS
310 320 330 340 350 360
RDVKTDAGPI HLSLAFNPSH LEFICPVAMG SVRARQERQN GHKRDYAMTV MIHGDASFSG
370 380 390 400 410 420
EGIVMEALSM SQTRAHHVGG SIHIILNNQV GFTTSNPHDA RSSMYCSDIA KMLDAPVFHV
430 440 450 460 470 480
NGDDPEAVVA VTQLALDYRM AFHKDVFIDL VCYRRHGHQE VDDPMPTQPA MYKVIQEHPT
490 500 510 520 530 540
TRTLYAKNLI EKKLCTAEEV DQWIDDYRDR LDRGRQLVET LPEGLSAHYA ANWTPYLGQD
550 560 570 580 590 600
WTTLVDTTLP LKKLKALGKK FSTLPNTLHL HRKVEAIYKA RLEMAEGKTP MDWGFAEMLA
610 620 630 640 650 660
YASLLEEGFS VRLVGQDSRR GTFFHRHAVV FDQETGKEYE PLKHLSDKQA APHIYDSLLC
670 680 690 700 710 720
EAGALGFEYG YSTADPNSLV IWEAQFGDFA NVAQVIVDQF ISSGWQKWNR LSGIVLFLPH
730 740 750 760 770 780
GYEGKGPEHS SARLERYLQL CAQNNMQVCA PTTPSQIFHL LRRQVLRPYR KPLVVLTPKS
790 800 810 820 830 840
VLRNKLAVSS LEDLARGQLK LLIPEIEKHD PKKITRVILC SGKVYYDLLA KRREHKGKLN
850 860 870 880 890 900
HIAMIRIEQL YPFPYDELKA ELEKYPNAKQ VIWCQEEPKN QGAWFCTRHR LIKCMRDDQT
910 920 930
LEYVGRSAFA APAAGYSALY VKLQEQLVNQ ALEI
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P51056 in FASTA format |
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