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UniProtKB/Swiss-Prot entry P50144

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name CCKN1_XENLA
Primary accession number P50144
Secondary accession numbers None
Integrated into Swiss-Prot on October 1, 1996
Sequence was last modified on October 1, 1996 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 46)
Name and origin of the protein
Protein name Cholecystokinin type 1 [Precursor]
Synonyms None
Contains Cholecystokinin
     (CCK)
Gene name
Name: cck-A
From
Xenopus laevis (African clawed frog) [TaxID: 8355] 
Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Mesobatrachia; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
Protein existence 2: Evidence at transcript level;
References
[1]
 NUCLEOTIDE SEQUENCE [MRNA].
TISSUE=Brain;
PubMed=7669225 [NCBI, ExPASy, EBI, Israel, Japan]
Wechselberger C., Kreil G.;
"Structure of two cDNAs encoding cholecystokinin precursors from the brain of Xenopus laevis.";
J. Mol. Endocrinol. 14:357-364(1995).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
Z47557; CAA87638.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR I51604; I51604.
RefSeq NP_001079303.1; -.
UniGene Xl.1146
3D structure databases
ModBase P50144.
Ontologies
GO
GO:0005576; Cellular component: extracellular region (inferred from electronic annotation from InterPro).
GO:0005179; Molecular function: hormone activity (inferred from electronic annotation from InterPro).
QuickGo view.
Family and domain databases
InterPro IPR015499; CCK.
IPR001651; Gastrin.
IPR013152; Gastrin_CCK_CS.
Graphical view of domain structure.
PANTHER PTHR10786; CCK; 1.
Pfam PF00918; Gastrin; 1.
Pfam graphical view of domain structure.
SMART SM00029; GASTRIN; 1.
SMART graphical view of domain structure.
PROSITE PS00259; GASTRIN; 1.
Genome annotation databases
GeneID 378611; -.
KEGG xla:378611; -.
Phylogenomic databases
HOVERGEN P50144; -.
Other
ProtoNet P50144.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Amidation; Cleavage on pair of basic residues; Hormone; Secreted; Signal; Sulfation.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
SIGNAL   1    20  20     Potential. 
PROPEP   21   103  83     Potential. PRO_0000010603
PEPTIDE   104   111  8     Cholecystokinin. PRO_0000010604
PROPEP   115   123  9     Potential. PRO_0000010605
MOD_RES   105   105        Sulfotyrosine (By similarity). 
MOD_RES   111   111        Phenylalanine amide (By similarity). 
Sequence information
Length: 123 AA [This is the length of the unprocessed precursor] Molecular weight: 13943 Da [This is the MW of the unprocessed precursor] CRC64: FBDCC9E150A98540 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MYSGICICLL LAMLSASSKA HQSEDAVVTE MDQLTLSQLP RYARASSAGQ KKSFQRTDGD 

        70         80         90        100        110        120 
QRSNIGNVLV KYLQQSRKAG PSGRYVVLPN RPIFDQPHRI NDRDYMGWMD FGRRSAEEYE 


YSS
P50144 in FASTA format

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