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UniProtKB/Swiss-Prot entry P49729


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name UCRI1_TOBAC
Primary accession number P49729
Secondary accession numbers None
Integrated into Swiss-Prot on October 1, 1996
Sequence was last modified on October 1, 1996 (Sequence version 1)
Annotations were last modified on    September 2, 2008 (Entry version 52)
Name and origin of the protein
Protein name Cytochrome b-c1 complex subunit Rieske-1, mitochondrial [Precursor] [Fragment]
Synonyms EC 1.10.2.2
Ubiquinol-cytochrome c reductase iron-sulfur subunit 1
Rieske iron-sulfur protein 1
RISP1
Complex III subunit 5-1
Gene name None
From
Nicotiana tabacum (Common tobacco) [TaxID: 4097] 
Taxonomy Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliophyta; eudicotyledons; core eudicotyledons; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana.
Protein existence 2: Evidence at transcript level;
References
[1]
NUCLEOTIDE SEQUENCE [MRNA].
TISSUE=Leaf;
PubMed=1961737 [NCBI, ExPASy, EBI, Israel, Japan]
Huang J.T., Struck F., Matzinger D.F., Levings C.S. III;
"Functional analysis in yeast of cDNA coding for the mitochondrial Rieske iron-sulfur protein of higher plants.";
Proc. Natl. Acad. Sci. U.S.A. 88:10716-10720(1991).
Comments
  • FUNCTION: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
  • CATALYTIC ACTIVITY: QH2 + 2 ferricytochrome c = Q + 2 ferrocytochrome c + 2 H+.
  • COFACTOR: Binds 1 2Fe-2S cluster per subunit (By similarity).
  • SUBUNIT: The bc1 complex contains 10 subunits; 3 respiratory subunits, 2 core proteins and 5 low-molecular weight proteins.
  • SUBCELLULAR LOCATION: Mitochondrion inner membrane.
  • MISCELLANEOUS: The Rieske protein is a high potential 2Fe-2S protein.
  • SIMILARITY: Contains 1 Rieske domain.
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
M77225; AAA34112.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR B41607; B41607.
3D structure databases
HSSP P13272; 1RIE. [HSSP ENTRY / PDB]
ModBase P49729.
Family and domain databases
InterPro IPR014349; Rieske.
IPR005805; Rieske_C.
IPR006317; Rieske_proteo.
IPR005806; Rieske_reg.
IPR004192; UCR_TM_region.
Graphical view of domain structure.
Gene3D G3DSA:2.102.10.10; Rieske_reg; 1.
PANTHER PTHR10134; Rieske; 1.
Pfam PF00355; Rieske; 1.
PF02921; UCR_TM; 1.
Pfam graphical view of domain structure.
PRINTS PR00162; RIESKE.
TIGRFAMs TIGR01416; Rieske_proteo; 1.
PROSITE PS51296; RIESKE; 1.
PROSITE graphical view of domain structure (profiles).
BLOCKS P49729.
Other
ProtoNet P49729.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
2Fe-2S; Electron transport; Iron; Iron-sulfur; Membrane; Metal-binding; Mitochondrion; Mitochondrion inner membrane; Oxidoreductase; Respiratory chain; Transit peptide; Transmembrane; Transport.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
TRANSIT   <1    46  >46     Mitochondrion (By similarity). 
CHAIN   47   258  212     Cytochrome b-c1 complex subunit Rieske-1, mitochondrial. PRO_0000030676
DOMAIN   161   256  96     Rieske. 
METAL   201   201        Iron-sulfur (2Fe-2S) (By similarity). 
METAL   203   203        Iron-sulfur (2Fe-2S); via pros nitrogen (By similarity). 
METAL   220   220        Iron-sulfur (2Fe-2S) (By similarity). 
METAL   223   223        Iron-sulfur (2Fe-2S); via pros nitrogen (By similarity). 
DISULFID   206   222        By similarity. 
NON_TER   1     1         
Sequence information
Length: 258 AA [This is the length of the partial sequence of the unprocessed precursor] Molecular weight: 28192 Da [This is the MW of the partial sequence of the unprocessed precursor] CRC64: FDA51B570CCEDCAF [This is a checksum on the sequence]
        10         20         30         40         50         60 
WPVRSAAPSS SAFISANHFS SDDDSSSPRS ISPSLASVFL HHTRGFSSNS VSPAHDMGLV 

        70         80         90        100        110        120 
PDLPPTVAAI KNPTSKIVYD EHNHERYPPG DPSKRAFAYF VLTGGRFVYA SLMRLLILKF 

       130        140        150        160        170        180 
VLSMSASKDV LALASLEVDL SSIEPGTTVT VKWRGKPVFI RRRTEDDISL ANSVDLGSLR 

       190        200        210        220        230        240 
DPQQDAERVK NPEWLVVIGV CTHLGCIPLP NAGDFGGWFC PCHGSHYDIS GRIRKGPAPY 

       250 
NLEVPTYSFL EENKLLIG 

P49729 in FASTA format

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